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Food Protein-Induced Enterocolitis Syndrome.

Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a rare, non-immunoglobulin E-mediated gastrointestinal food allergy primarily diagnosed in infancy, but has also been reported in older children and adults. Acute FPIES reactions typically present with delayed, repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. Chronic FPIES typically presents with protracted vomiting and/or diarrhea, and weight loss or poor growth. Common foods triggering FPIES include cow's milk, soy, rice, oats, fish, and egg. More detailed diagnostic criteria may help in increasing awareness of FPIES and reducing delayed diagnoses or misdiagnoses.

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  • Authors+Show Affiliations

    ,

    Division of Pediatric Allergy & Immunology, Rady Children's Hospital San Diego, University of California, San Diego, 3020 Children's Way, MC 5114, San Diego, CA 92123, USA.

    Division of Pediatric Allergy, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, Box 1198, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address: anna.nowak-wegrzyn@mssm.edu.

    Source

    Pediatric clinics of North America 62:6 2015 Dec pg 1463-77

    MeSH

    Child
    Diagnosis, Differential
    Diarrhea
    Dietary Proteins
    Enterocolitis
    Food Hypersensitivity
    Humans
    Lethargy
    Pallor
    Syndrome
    Vomiting
    Weight Loss

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    26456444

    Citation

    Leonard, Stephanie A., and Anna Nowak-Węgrzyn. "Food Protein-Induced Enterocolitis Syndrome." Pediatric Clinics of North America, vol. 62, no. 6, 2015, pp. 1463-77.
    Leonard SA, Nowak-Węgrzyn A. Food Protein-Induced Enterocolitis Syndrome. Pediatr Clin North Am. 2015;62(6):1463-77.
    Leonard, S. A., & Nowak-Węgrzyn, A. (2015). Food Protein-Induced Enterocolitis Syndrome. Pediatric Clinics of North America, 62(6), pp. 1463-77. doi:10.1016/j.pcl.2015.07.011.
    Leonard SA, Nowak-Węgrzyn A. Food Protein-Induced Enterocolitis Syndrome. Pediatr Clin North Am. 2015;62(6):1463-77. PubMed PMID: 26456444.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Food Protein-Induced Enterocolitis Syndrome. AU - Leonard,Stephanie A, AU - Nowak-Węgrzyn,Anna, PY - 2015/10/13/entrez PY - 2015/10/13/pubmed PY - 2016/1/12/medline KW - FPIES KW - Food protein–induced enterocolitis syndrome KW - Gastrointestinal food allergy KW - Non–IgE-mediated food allergy SP - 1463 EP - 77 JF - Pediatric clinics of North America JO - Pediatr. Clin. North Am. VL - 62 IS - 6 N2 - Food protein-induced enterocolitis syndrome (FPIES) is a rare, non-immunoglobulin E-mediated gastrointestinal food allergy primarily diagnosed in infancy, but has also been reported in older children and adults. Acute FPIES reactions typically present with delayed, repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. Chronic FPIES typically presents with protracted vomiting and/or diarrhea, and weight loss or poor growth. Common foods triggering FPIES include cow's milk, soy, rice, oats, fish, and egg. More detailed diagnostic criteria may help in increasing awareness of FPIES and reducing delayed diagnoses or misdiagnoses. SN - 1557-8240 UR - https://www.unboundmedicine.com/medline/citation/26456444/Food_Protein_Induced_Enterocolitis_Syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-3955(15)00134-0 DB - PRIME DP - Unbound Medicine ER -