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Light chain multiple myeloma presenting with spinal plasmacytoma: Unusual radiological appearance mimicking giant cell tumor.
J Cancer Res Ther. 2015 Jul-Sep; 11(3):648.JC

Abstract

Plasmacytoma, an initial presentation of multiple myeloma, is extremely rare and an unusual cause of spinal cord compression in a young male. A 35-year-old man presented with complaints of progressive weakness and tingling of bilateral lower limbs, severe backache for 3 months, and bladder and bowel incontinence for 1 week duration. Imaging demonstrated lytic destruction of 10 th and 11 th dorsal vertebrae with large soft tissue component and compression of the spinal cord. Biopsy was performed under computed tomography guidance and the histopathology demonstrated presence of plasmacytoma. Serum electrophoresis and bone marrow examination confirmed the diagnosis of light chain multiple myeloma. Though the magnetic resonance imaging the appearance of spinal plasmacytoma is nonspecific, a minibrain appearance has been considered pathognomonic. This case is reported for the unusual radiological appearance of this entity mimicking giant cell tumor.

Authors+Show Affiliations

No affiliation info availableDepartment of Radiodiagnosis, Employees State Insurance Hospital and Post Graduate Institutue of Medical Science and Research, Delhi, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Letter

Language

eng

PubMed ID

26458612

Citation

Satija, Bhawna, et al. "Light Chain Multiple Myeloma Presenting With Spinal Plasmacytoma: Unusual Radiological Appearance Mimicking Giant Cell Tumor." Journal of Cancer Research and Therapeutics, vol. 11, no. 3, 2015, p. 648.
Satija B, Gupta R, Kumar S, et al. Light chain multiple myeloma presenting with spinal plasmacytoma: Unusual radiological appearance mimicking giant cell tumor. J Cancer Res Ther. 2015;11(3):648.
Satija, B., Gupta, R., Kumar, S., & Chandoke, R. (2015). Light chain multiple myeloma presenting with spinal plasmacytoma: Unusual radiological appearance mimicking giant cell tumor. Journal of Cancer Research and Therapeutics, 11(3), 648. https://doi.org/10.4103/0973-1482.137922
Satija B, et al. Light Chain Multiple Myeloma Presenting With Spinal Plasmacytoma: Unusual Radiological Appearance Mimicking Giant Cell Tumor. J Cancer Res Ther. 2015 Jul-Sep;11(3):648. PubMed PMID: 26458612.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Light chain multiple myeloma presenting with spinal plasmacytoma: Unusual radiological appearance mimicking giant cell tumor. AU - Satija,Bhawna, AU - Gupta,Rajat, AU - Kumar,Sanyal, AU - Chandoke,Raj, PY - 2015/10/14/entrez PY - 2015/10/16/pubmed PY - 2016/8/26/medline SP - 648 EP - 648 JF - Journal of cancer research and therapeutics JO - J Cancer Res Ther VL - 11 IS - 3 N2 - Plasmacytoma, an initial presentation of multiple myeloma, is extremely rare and an unusual cause of spinal cord compression in a young male. A 35-year-old man presented with complaints of progressive weakness and tingling of bilateral lower limbs, severe backache for 3 months, and bladder and bowel incontinence for 1 week duration. Imaging demonstrated lytic destruction of 10 th and 11 th dorsal vertebrae with large soft tissue component and compression of the spinal cord. Biopsy was performed under computed tomography guidance and the histopathology demonstrated presence of plasmacytoma. Serum electrophoresis and bone marrow examination confirmed the diagnosis of light chain multiple myeloma. Though the magnetic resonance imaging the appearance of spinal plasmacytoma is nonspecific, a minibrain appearance has been considered pathognomonic. This case is reported for the unusual radiological appearance of this entity mimicking giant cell tumor. SN - 1998-4138 UR - https://www.unboundmedicine.com/medline/citation/26458612/Light_chain_multiple_myeloma_presenting_with_spinal_plasmacytoma:_Unusual_radiological_appearance_mimicking_giant_cell_tumor_ L2 - http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2015;volume=11;issue=3;spage=648;epage=648;aulast=Satija DB - PRIME DP - Unbound Medicine ER -