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Correlation of narrow band imaging endoscopy and histopathology in the diagnosis of nonerosive reflux disease.
Saudi J Gastroenterol. 2015 Sep-Oct; 21(5):330-6.SJ

Abstract

Background /Aim: Narrow band imaging (NBI) is a novel, innovative high-resolution endoscopic technique, which utilizes spectral narrow band filter for the visualization of mucosal patterns and microvasculature. Nonerosive reflux disease (NERD) is a type of gastroesophageal reflux disease (GERD) and it is characterized by reflux symptoms without mucosal breaks on white light endoscopy (WLE). Biopsies from distal esophagus of GERD patients show group of histologic features such as basal cell hyperplasia, elongation of lamina propria papillae, and inflammatory cells. The present study was undertaken to evaluate diagnostic utility of NBI endoscopy and biopsy study in NERD patients and also to correlate NBI endoscopy findings with histologic features of GERD.

PATIENTS AND METHODS

A total of 71 cases of NERD having symptom score more than 10 and those not having erosion on WLE were recruited prospectively and underwent NBI endoscopic examination. Two mucosal biopsies were taken at 3 cm above the squamocolumnar junction.

RESULTS

Histologic features of GERD were seen in 50 (70.4%) out of 71 cases. No significant correlation between NBI endoscopic findings with histologic features of GERD was found.

CONCLUSION

The present study showed that histopathologic evaluation of distal esophageal mucosa has promising diagnostic value over NBI endoscopy in NERD patients. Use of newly introduced NBI technique requires tremendous familiarity for the detection of the cases of NERD, which show histologic features of GERD.

Authors+Show Affiliations

Department of Pathology, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Perambalur, Tamil Nadu, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26458862

Citation

Arul, P, et al. "Correlation of Narrow Band Imaging Endoscopy and Histopathology in the Diagnosis of Nonerosive Reflux Disease." Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association, vol. 21, no. 5, 2015, pp. 330-6.
Arul P, Vinoth B, Alexander T, et al. Correlation of narrow band imaging endoscopy and histopathology in the diagnosis of nonerosive reflux disease. Saudi J Gastroenterol. 2015;21(5):330-6.
Arul, P., Vinoth, B., Alexander, T., Phansalkar, M., & Padhi, S. (2015). Correlation of narrow band imaging endoscopy and histopathology in the diagnosis of nonerosive reflux disease. Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association, 21(5), 330-6. https://doi.org/10.4103/1319-3767.164205
Arul P, et al. Correlation of Narrow Band Imaging Endoscopy and Histopathology in the Diagnosis of Nonerosive Reflux Disease. Saudi J Gastroenterol. 2015 Sep-Oct;21(5):330-6. PubMed PMID: 26458862.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation of narrow band imaging endoscopy and histopathology in the diagnosis of nonerosive reflux disease. AU - Arul,P, AU - Vinoth,B, AU - Alexander,Thomas, AU - Phansalkar,Manjiri, AU - Padhi,Somanath, PY - 2015/10/14/entrez PY - 2015/10/16/pubmed PY - 2016/8/30/medline SP - 330 EP - 6 JF - Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association JO - Saudi J Gastroenterol VL - 21 IS - 5 N2 - UNLABELLED: Background /Aim: Narrow band imaging (NBI) is a novel, innovative high-resolution endoscopic technique, which utilizes spectral narrow band filter for the visualization of mucosal patterns and microvasculature. Nonerosive reflux disease (NERD) is a type of gastroesophageal reflux disease (GERD) and it is characterized by reflux symptoms without mucosal breaks on white light endoscopy (WLE). Biopsies from distal esophagus of GERD patients show group of histologic features such as basal cell hyperplasia, elongation of lamina propria papillae, and inflammatory cells. The present study was undertaken to evaluate diagnostic utility of NBI endoscopy and biopsy study in NERD patients and also to correlate NBI endoscopy findings with histologic features of GERD. PATIENTS AND METHODS: A total of 71 cases of NERD having symptom score more than 10 and those not having erosion on WLE were recruited prospectively and underwent NBI endoscopic examination. Two mucosal biopsies were taken at 3 cm above the squamocolumnar junction. RESULTS: Histologic features of GERD were seen in 50 (70.4%) out of 71 cases. No significant correlation between NBI endoscopic findings with histologic features of GERD was found. CONCLUSION: The present study showed that histopathologic evaluation of distal esophageal mucosa has promising diagnostic value over NBI endoscopy in NERD patients. Use of newly introduced NBI technique requires tremendous familiarity for the detection of the cases of NERD, which show histologic features of GERD. SN - 1998-4049 UR - https://www.unboundmedicine.com/medline/citation/26458862/Correlation_of_narrow_band_imaging_endoscopy_and_histopathology_in_the_diagnosis_of_nonerosive_reflux_disease_ L2 - http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=5;spage=330;epage=336;aulast=Arul DB - PRIME DP - Unbound Medicine ER -