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Reevaluating the prevalence and diagnostic subtypes of depressive disorders in epilepsy.
Epilepsy Behav. 2015 Dec; 53:15-9.EB

Abstract

OBJECTIVE

Depressive disorders are common among patients with epilepsy (PWE). The aim of this study was to estimate the prevalence of different forms of depressive disorders among PWE treated in the outpatient setting.

METHODS

A group of consecutive PWE that visited the epilepsy outpatient clinic was invited to participate in the study. Ninety-six patients met inclusion criteria and were examined by a trained psychiatrist using standardized measures.

RESULTS

A diagnosis of a current major depression was established in 21 (22.3%) out of 96 participants. Furthermore, almost 20% of the study group fulfilled criteria for mood disorder categories other than MDD, adding up to over 40% of PWE suffering from any mood disorder category. Older age and later age at seizure onset, as well as unemployment, were associated with an increase in the odds of MDD diagnosis.

STUDY LIMITATIONS

A number of limitations are to be considered: the sample size is relatively small, and the findings may not be representative of PWE in general because our population represents a sample coming from a single outpatient clinic with a higher ratio of drug-resistant epilepsy.

CONCLUSIONS

Major depression as well as other forms of depressive disorders are common among PWE. Unemployment, age, and age at seizure onset are important factors associated with major depression among PWE.

Authors+Show Affiliations

Department of Psychiatry, Medical University of Gdańsk, Poland. Electronic address: mwiglusz@gumed.edu.pl.Department of Psychiatry, Medical University of Gdańsk, Poland.Regional Epilepsy Outpatient Unit, Copernicus Hospital, Gdańsk, Poland.Department of Psychiatry, Medical University of Gdańsk, Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26515153

Citation

Wiglusz, Mariusz S., et al. "Reevaluating the Prevalence and Diagnostic Subtypes of Depressive Disorders in Epilepsy." Epilepsy & Behavior : E&B, vol. 53, 2015, pp. 15-9.
Wiglusz MS, Landowski J, Michalak L, et al. Reevaluating the prevalence and diagnostic subtypes of depressive disorders in epilepsy. Epilepsy Behav. 2015;53:15-9.
Wiglusz, M. S., Landowski, J., Michalak, L., & Cubała, W. J. (2015). Reevaluating the prevalence and diagnostic subtypes of depressive disorders in epilepsy. Epilepsy & Behavior : E&B, 53, 15-9. https://doi.org/10.1016/j.yebeh.2015.09.029
Wiglusz MS, et al. Reevaluating the Prevalence and Diagnostic Subtypes of Depressive Disorders in Epilepsy. Epilepsy Behav. 2015;53:15-9. PubMed PMID: 26515153.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reevaluating the prevalence and diagnostic subtypes of depressive disorders in epilepsy. AU - Wiglusz,Mariusz S, AU - Landowski,Jerzy, AU - Michalak,Lidia, AU - Cubała,Wiesław J, Y1 - 2015/10/26/ PY - 2015/07/15/received PY - 2015/09/20/revised PY - 2015/09/21/accepted PY - 2015/10/31/entrez PY - 2015/10/31/pubmed PY - 2016/7/12/medline KW - DSM-IV-TR KW - Depressive disorders KW - Epidemiology KW - Epilepsy KW - Major depressive disorder KW - SCID-I SP - 15 EP - 9 JF - Epilepsy & behavior : E&B JO - Epilepsy Behav VL - 53 N2 - OBJECTIVE: Depressive disorders are common among patients with epilepsy (PWE). The aim of this study was to estimate the prevalence of different forms of depressive disorders among PWE treated in the outpatient setting. METHODS: A group of consecutive PWE that visited the epilepsy outpatient clinic was invited to participate in the study. Ninety-six patients met inclusion criteria and were examined by a trained psychiatrist using standardized measures. RESULTS: A diagnosis of a current major depression was established in 21 (22.3%) out of 96 participants. Furthermore, almost 20% of the study group fulfilled criteria for mood disorder categories other than MDD, adding up to over 40% of PWE suffering from any mood disorder category. Older age and later age at seizure onset, as well as unemployment, were associated with an increase in the odds of MDD diagnosis. STUDY LIMITATIONS: A number of limitations are to be considered: the sample size is relatively small, and the findings may not be representative of PWE in general because our population represents a sample coming from a single outpatient clinic with a higher ratio of drug-resistant epilepsy. CONCLUSIONS: Major depression as well as other forms of depressive disorders are common among PWE. Unemployment, age, and age at seizure onset are important factors associated with major depression among PWE. SN - 1525-5069 UR - https://www.unboundmedicine.com/medline/citation/26515153/Reevaluating_the_prevalence_and_diagnostic_subtypes_of_depressive_disorders_in_epilepsy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1525-5050(15)00551-X DB - PRIME DP - Unbound Medicine ER -