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Crofelemer for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy.
Expert Rev Clin Pharmacol 2015; 8(6):683-90ER

Abstract

Chronic diarrhea remains a common condition that affects people infected with human immunodeficiency virus (HIV) despite the widespread use of potent antiretroviral therapy. It is important that providers control this condition, as the persistence of diarrhea affects the quality of life of patients and may contribute to decreased adherence to antiretroviral therapy. Strategies to control diarrhea in patients with HIV infection include switching to a new antiretroviral regimen and/or the use of specific medications to control the diarrhea. This review aims to provide a concise evaluation of a newly approved medication (crofelemer) that has a novel mechanism of action and has received approval for the symptomatic relief of non-infectious diarrhea in adult patients with HIV on anti-retroviral therapy.

Authors+Show Affiliations

a 1 Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine , Miami, FL, USA. b 2 Clinical Research Building , 1120 NW 14th Street, Suite 857, Miami, FL 33136, USA.c 3 Clinical Hospital Pharmacist, Pharmacy Department, Jackson Memorial Hospital , Miami, FL, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26517110

Citation

Castro, Jose G., and Nafeesa Chin-Beckford. "Crofelemer for the Symptomatic Relief of Non-infectious Diarrhea in Adult Patients With HIV/AIDS On Anti-retroviral Therapy." Expert Review of Clinical Pharmacology, vol. 8, no. 6, 2015, pp. 683-90.
Castro JG, Chin-Beckford N. Crofelemer for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy. Expert Rev Clin Pharmacol. 2015;8(6):683-90.
Castro, J. G., & Chin-Beckford, N. (2015). Crofelemer for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy. Expert Review of Clinical Pharmacology, 8(6), pp. 683-90. doi:10.1586/17512433.2015.1082424.
Castro JG, Chin-Beckford N. Crofelemer for the Symptomatic Relief of Non-infectious Diarrhea in Adult Patients With HIV/AIDS On Anti-retroviral Therapy. Expert Rev Clin Pharmacol. 2015;8(6):683-90. PubMed PMID: 26517110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Crofelemer for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy. AU - Castro,Jose G, AU - Chin-Beckford,Nafeesa, Y1 - 2015/08/27/ PY - 2015/10/31/entrez PY - 2015/11/1/pubmed PY - 2016/6/2/medline KW - AIDS KW - HIV KW - crofelemer KW - diarrhea KW - secretory diarrhea KW - side effects antiretrovirals KW - treatment diarrhea SP - 683 EP - 90 JF - Expert review of clinical pharmacology JO - Expert Rev Clin Pharmacol VL - 8 IS - 6 N2 - Chronic diarrhea remains a common condition that affects people infected with human immunodeficiency virus (HIV) despite the widespread use of potent antiretroviral therapy. It is important that providers control this condition, as the persistence of diarrhea affects the quality of life of patients and may contribute to decreased adherence to antiretroviral therapy. Strategies to control diarrhea in patients with HIV infection include switching to a new antiretroviral regimen and/or the use of specific medications to control the diarrhea. This review aims to provide a concise evaluation of a newly approved medication (crofelemer) that has a novel mechanism of action and has received approval for the symptomatic relief of non-infectious diarrhea in adult patients with HIV on anti-retroviral therapy. SN - 1751-2441 UR - https://www.unboundmedicine.com/medline/citation/26517110/Crofelemer_for_the_symptomatic_relief_of_non-infectious_diarrhea_in_adult_patients_with_HIV/AIDS_on_anti-retroviral_therapy L2 - http://www.tandfonline.com/doi/full/10.1586/17512433.2015.1082424 DB - PRIME DP - Unbound Medicine ER -