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Erythropoietin in renal transplant recipients: studies based on recombinant human erythropoietin radioimmunoassay.
Transplant Proc. 1989 Feb; 21(1 Pt 2):2041-2.TP

Abstract

In posttransplant patients, modest increases in endogenous EPO induce erythropoiesis similar to that observed in uremic patients who are given large doses of exogenous rHuEPO that generate vastly higher circulating EPO levels. Moreover, once it is initiated, erythropoiesis may be sustained by normal levels of EPO. These observations raise the possibility that the restoration of renal function may alter the EPO-erythropoiesis response pattern. It is also possible that the resolution of uremic anemia is dependent on factors in addition to the level of circulating EPO.

Authors+Show Affiliations

Harbor-UCLA Medical Center, Torrance.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

2652668

Citation

Ward, H J., et al. "Erythropoietin in Renal Transplant Recipients: Studies Based On Recombinant Human Erythropoietin Radioimmunoassay." Transplantation Proceedings, vol. 21, no. 1 Pt 2, 1989, pp. 2041-2.
Ward HJ, Sun CH, Paul WL, et al. Erythropoietin in renal transplant recipients: studies based on recombinant human erythropoietin radioimmunoassay. Transplant Proc. 1989;21(1 Pt 2):2041-2.
Ward, H. J., Sun, C. H., Paul, W. L., Koyle, M. A., Yanagawa, N., & Lee, D. B. (1989). Erythropoietin in renal transplant recipients: studies based on recombinant human erythropoietin radioimmunoassay. Transplantation Proceedings, 21(1 Pt 2), 2041-2.
Ward HJ, et al. Erythropoietin in Renal Transplant Recipients: Studies Based On Recombinant Human Erythropoietin Radioimmunoassay. Transplant Proc. 1989;21(1 Pt 2):2041-2. PubMed PMID: 2652668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Erythropoietin in renal transplant recipients: studies based on recombinant human erythropoietin radioimmunoassay. AU - Ward,H J, AU - Sun,C H, AU - Paul,W L, AU - Koyle,M A, AU - Yanagawa,N, AU - Lee,D B, PY - 1989/2/1/pubmed PY - 1989/2/1/medline PY - 1989/2/1/entrez SP - 2041 EP - 2 JF - Transplantation proceedings JO - Transplant Proc VL - 21 IS - 1 Pt 2 N2 - In posttransplant patients, modest increases in endogenous EPO induce erythropoiesis similar to that observed in uremic patients who are given large doses of exogenous rHuEPO that generate vastly higher circulating EPO levels. Moreover, once it is initiated, erythropoiesis may be sustained by normal levels of EPO. These observations raise the possibility that the restoration of renal function may alter the EPO-erythropoiesis response pattern. It is also possible that the resolution of uremic anemia is dependent on factors in addition to the level of circulating EPO. SN - 0041-1345 UR - https://www.unboundmedicine.com/medline/citation/2652668/Erythropoietin_in_renal_transplant_recipients:_studies_based_on_recombinant_human_erythropoietin_radioimmunoassay_ L2 - https://medlineplus.gov/kidneytransplantation.html DB - PRIME DP - Unbound Medicine ER -