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Extrapancreatic gastrinoma with pancreatic islet cell hyperplasia.
Arch Pathol Lab Med. 1989 May; 113(5):536-8.AP

Abstract

A case of Zollinger-Ellison syndrome was associated with diffuse islet cell hyperplasia of the pancreas and extrapancreatic gastrinoma. At autopsy, the patient, who had well-documented Zollinger-Ellison syndrome, was found to have gastrinoma in parapancreatic lymph nodes with islet cell hyperplasia but no evidence of pancreatic neoplasm. Possible explanations include the production of a trophic factor by the extrapancreatic gastrinoma, leading to islet cell hyperplasia, or metastasis from a microscopic nodule of gastrin cells that, despite having a "hyperplastic" appearance, exhibited malignant potential.

Authors+Show Affiliations

Department of Laboratories, Mount Sinai Medical Center, Cleveland, OH 44106.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2653274

Citation

Sawady, J, and G Mendelsohn. "Extrapancreatic Gastrinoma With Pancreatic Islet Cell Hyperplasia." Archives of Pathology & Laboratory Medicine, vol. 113, no. 5, 1989, pp. 536-8.
Sawady J, Mendelsohn G. Extrapancreatic gastrinoma with pancreatic islet cell hyperplasia. Arch Pathol Lab Med. 1989;113(5):536-8.
Sawady, J., & Mendelsohn, G. (1989). Extrapancreatic gastrinoma with pancreatic islet cell hyperplasia. Archives of Pathology & Laboratory Medicine, 113(5), 536-8.
Sawady J, Mendelsohn G. Extrapancreatic Gastrinoma With Pancreatic Islet Cell Hyperplasia. Arch Pathol Lab Med. 1989;113(5):536-8. PubMed PMID: 2653274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extrapancreatic gastrinoma with pancreatic islet cell hyperplasia. AU - Sawady,J, AU - Mendelsohn,G, PY - 1989/5/1/pubmed PY - 1989/5/1/medline PY - 1989/5/1/entrez SP - 536 EP - 8 JF - Archives of pathology & laboratory medicine JO - Arch Pathol Lab Med VL - 113 IS - 5 N2 - A case of Zollinger-Ellison syndrome was associated with diffuse islet cell hyperplasia of the pancreas and extrapancreatic gastrinoma. At autopsy, the patient, who had well-documented Zollinger-Ellison syndrome, was found to have gastrinoma in parapancreatic lymph nodes with islet cell hyperplasia but no evidence of pancreatic neoplasm. Possible explanations include the production of a trophic factor by the extrapancreatic gastrinoma, leading to islet cell hyperplasia, or metastasis from a microscopic nodule of gastrin cells that, despite having a "hyperplastic" appearance, exhibited malignant potential. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/2653274/Extrapancreatic_gastrinoma_with_pancreatic_islet_cell_hyperplasia_ L2 - http://www.diseaseinfosearch.org/result/8684 DB - PRIME DP - Unbound Medicine ER -