Tags

Type your tag names separated by a space and hit enter

[Benign proliferative breast disease with and without atypia].
J Gynecol Obstet Biol Reprod (Paris). 2015 Dec; 44(10):980-95.JG

Abstract

In the last few years, diagnostics of high-risk breast lesions (atypical ductal hyperplasia [ADH], flat epithelial atypia [FEA], lobular neoplasia: atypical lobular hyperplasia [ALH], lobular carcinoma in situ [LCIS], radial scar [RS], usual ductal hyperplasia [UDH], adenosis, sclerosing adenosis [SA], papillary breast lesions, mucocele-like lesion [MLL]) have increased with the growing number of breast percutaneous biopsies. The management of these lesions is highly conditioned by the enlarged risk of breast cancer combined with either an increased probability of finding cancer after surgery, either a possible malignant transformation (in situ or invasive cancer), or an increased probability of developing cancer on the long range. An overview of the literature reports grade C recommendations concerning the management and follow-up of these lesions: in case of ADH, FEA, ALH, LCIS, RS, MLL with atypia, diagnosed on percutaneous biopsies: surgical excision is recommended; in case of a diagnostic based on vacuum-assisted core biopsy with complete disappearance of radiological signal for FEA or RS without atypia: surgical abstention is a valid alternative approved by multidisciplinary meeting. In case of ALH (incidental finding) associated with benign lesion responsible of radiological signal: abstention may be proposed; in case of UDH, adenosis, MLL without atypia, diagnosed on percutaneous biopsies: the concordance of radiology and histopathology findings must be ensured. No data is available to recommend surgery; in case of non-in sano resection for ADH, FEA, ALH, LCIS (except pleomorphic type), RS, MLL: surgery does not seem to be necessary; in case of previous ADH, ALH, LCIS: a specific follow-up is recommended in accordance with HAS's recommendations. In case of FEA and RS or MLL combined with atypia, little data are yet available to differ the management from others lesions with atypia; in case of UDH, usual sclerosing adenosis, RS without atypia, fibro cystic disease: no specific follow-up is recommended in agreement with HAS's recommendations.

Authors+Show Affiliations

Département d'oncologie chirurgicale, centre de lutte contre le cancer Georges-François-Leclerc - Unicancer, 1, rue Professeur-Marion, BP 77980, 21079 Dijon cedex, France; Université de Bourgogne-Franche Comté, esplanade Erasme, 21078 Dijon cedex, France. Electronic address: ccoutant@cgfl.fr.Inserm UMRS938, service de gynécologie obstétrique et médecine de la reproduction, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.Inserm UMRS707, service de gynécologie obstétrique et médecine de la reproduction, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.Université de Bourgogne-Franche Comté, esplanade Erasme, 21078 Dijon cedex, France; Département de pathologie des tumeurs, centre de lutte contre le cancer Georges-François-Leclerc - Unicancer, 1, rue Professeur-Marion, BP 77980, 21079 Dijon cedex, France.

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

26545856

Citation

Coutant, C, et al. "[Benign Proliferative Breast Disease With and Without Atypia]." Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, vol. 44, no. 10, 2015, pp. 980-95.
Coutant C, Canlorbe G, Bendifallah S, et al. [Benign proliferative breast disease with and without atypia]. J Gynecol Obstet Biol Reprod (Paris). 2015;44(10):980-95.
Coutant, C., Canlorbe, G., Bendifallah, S., & Beltjens, F. (2015). [Benign proliferative breast disease with and without atypia]. Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction, 44(10), 980-95. https://doi.org/10.1016/j.jgyn.2015.09.037
Coutant C, et al. [Benign Proliferative Breast Disease With and Without Atypia]. J Gynecol Obstet Biol Reprod (Paris). 2015;44(10):980-95. PubMed PMID: 26545856.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Benign proliferative breast disease with and without atypia]. AU - Coutant,C, AU - Canlorbe,G, AU - Bendifallah,S, AU - Beltjens,F, Y1 - 2015/11/03/ PY - 2015/09/15/received PY - 2015/09/18/accepted PY - 2015/11/8/entrez PY - 2015/11/8/pubmed PY - 2016/9/16/medline KW - Adenosis KW - Adénose KW - Atypical ductal neoplasia KW - Cicatrices radiaires KW - Flat epithelial atypia KW - High-risk breast lesion KW - Hyperplasie canalaire atypique KW - Lobular neoplasia KW - Lésions frontières du sein KW - Lésions prolifératives apocrines KW - Mucocèles KW - Métaplasie cylindrique avec atypie KW - Néoplasies lobulaires KW - Papillary breast lesions KW - Proliférations épithéliales sans atypie KW - Radial scar KW - Sclerosing adenosis SP - 980 EP - 95 JF - Journal de gynecologie, obstetrique et biologie de la reproduction JO - J Gynecol Obstet Biol Reprod (Paris) VL - 44 IS - 10 N2 - In the last few years, diagnostics of high-risk breast lesions (atypical ductal hyperplasia [ADH], flat epithelial atypia [FEA], lobular neoplasia: atypical lobular hyperplasia [ALH], lobular carcinoma in situ [LCIS], radial scar [RS], usual ductal hyperplasia [UDH], adenosis, sclerosing adenosis [SA], papillary breast lesions, mucocele-like lesion [MLL]) have increased with the growing number of breast percutaneous biopsies. The management of these lesions is highly conditioned by the enlarged risk of breast cancer combined with either an increased probability of finding cancer after surgery, either a possible malignant transformation (in situ or invasive cancer), or an increased probability of developing cancer on the long range. An overview of the literature reports grade C recommendations concerning the management and follow-up of these lesions: in case of ADH, FEA, ALH, LCIS, RS, MLL with atypia, diagnosed on percutaneous biopsies: surgical excision is recommended; in case of a diagnostic based on vacuum-assisted core biopsy with complete disappearance of radiological signal for FEA or RS without atypia: surgical abstention is a valid alternative approved by multidisciplinary meeting. In case of ALH (incidental finding) associated with benign lesion responsible of radiological signal: abstention may be proposed; in case of UDH, adenosis, MLL without atypia, diagnosed on percutaneous biopsies: the concordance of radiology and histopathology findings must be ensured. No data is available to recommend surgery; in case of non-in sano resection for ADH, FEA, ALH, LCIS (except pleomorphic type), RS, MLL: surgery does not seem to be necessary; in case of previous ADH, ALH, LCIS: a specific follow-up is recommended in accordance with HAS's recommendations. In case of FEA and RS or MLL combined with atypia, little data are yet available to differ the management from others lesions with atypia; in case of UDH, usual sclerosing adenosis, RS without atypia, fibro cystic disease: no specific follow-up is recommended in agreement with HAS's recommendations. SN - 1773-0430 UR - https://www.unboundmedicine.com/medline/citation/26545856/[Benign_proliferative_breast_disease_with_and_without_atypia]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0368-2315(15)00277-X DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.