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Constituents and Pharmacological Activities of Myrcia (Myrtaceae): A Review of an Aromatic and Medicinal Group of Plants.
Int J Mol Sci 2015; 16(10):23881-904IJ

Abstract

Myrcia is one of the largest genera of the economically important family Myrtaceae. Some of the species are used in folk medicine, such as a group known as "pedra-hume-caá" or "pedra-ume-caá" or "insulina vegetal" (insulin plant) that it is used for the treatment of diabetes. The species are an important source of essential oils, and most of the chemical studies on Myrcia describe the chemical composition of the essential oils, in which mono- and sesquiterpenes are predominant. The non-volatile compounds isolated from Myrcia are usually flavonoids, tannins, acetophenone derivatives and triterpenes. Anti-inflammatory, antinociceptive, antioxidant, antimicrobial activities have been described to Myrcia essential oils, while hypoglycemic, anti-hemorrhagic and antioxidant activities were attributed to the extracts. Flavonoid glucosides and acetophenone derivatives showed aldose reductase and α-glucosidase inhibition, and could explain the traditional use of Myrcia species to treat diabetes. Antimicrobial and anti-inflammatory are some of the activities observed for other isolated compounds from Myrcia.

Authors+Show Affiliations

Programa de Pós-graduação em Química, Universidade Federal do Pará, Belém 66075-110, PA, Brazil. cascaesmm@gmail.com.Programa de Pós-graduação em Química, Universidade Federal do Pará, Belém 66075-110, PA, Brazil. giselle@ufpa.br.Programa de Pós-graduação em Química, Universidade Federal do Pará, Belém 66075-110, PA, Brazil. eloisandrade@ufpa.br.Museu Paraense Emílio Goeldi, Belém 66040-170, PA, Brazil. gracazoghbi@gmail.com.Programa de Pós-graduação em Química, Universidade Federal do Pará, Belém 66075-110, PA, Brazil. lss@ufpa.br.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

26556334

Citation

Cascaes, Márcia Moraes, et al. "Constituents and Pharmacological Activities of Myrcia (Myrtaceae): a Review of an Aromatic and Medicinal Group of Plants." International Journal of Molecular Sciences, vol. 16, no. 10, 2015, pp. 23881-904.
Cascaes MM, Guilhon GM, Andrade EH, et al. Constituents and Pharmacological Activities of Myrcia (Myrtaceae): A Review of an Aromatic and Medicinal Group of Plants. Int J Mol Sci. 2015;16(10):23881-904.
Cascaes, M. M., Guilhon, G. M., Andrade, E. H., Zoghbi, M. d., & Santos, L. d. a. . S. (2015). Constituents and Pharmacological Activities of Myrcia (Myrtaceae): A Review of an Aromatic and Medicinal Group of Plants. International Journal of Molecular Sciences, 16(10), pp. 23881-904. doi:10.3390/ijms161023881.
Cascaes MM, et al. Constituents and Pharmacological Activities of Myrcia (Myrtaceae): a Review of an Aromatic and Medicinal Group of Plants. Int J Mol Sci. 2015 Oct 9;16(10):23881-904. PubMed PMID: 26556334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Constituents and Pharmacological Activities of Myrcia (Myrtaceae): A Review of an Aromatic and Medicinal Group of Plants. AU - Cascaes,Márcia Moraes, AU - Guilhon,Giselle Maria Skelding Pinheiro, AU - Andrade,Eloisa Helena de Aguiar, AU - Zoghbi,Maria das Graças Bichara, AU - Santos,Lourivaldo da Silva, Y1 - 2015/10/09/ PY - 2015/08/13/received PY - 2015/09/24/revised PY - 2015/09/25/accepted PY - 2015/11/12/entrez PY - 2015/11/12/pubmed PY - 2016/8/20/medline KW - Myrcia KW - biological activities KW - non-volatiles KW - volatiles SP - 23881 EP - 904 JF - International journal of molecular sciences JO - Int J Mol Sci VL - 16 IS - 10 N2 - Myrcia is one of the largest genera of the economically important family Myrtaceae. Some of the species are used in folk medicine, such as a group known as "pedra-hume-caá" or "pedra-ume-caá" or "insulina vegetal" (insulin plant) that it is used for the treatment of diabetes. The species are an important source of essential oils, and most of the chemical studies on Myrcia describe the chemical composition of the essential oils, in which mono- and sesquiterpenes are predominant. The non-volatile compounds isolated from Myrcia are usually flavonoids, tannins, acetophenone derivatives and triterpenes. Anti-inflammatory, antinociceptive, antioxidant, antimicrobial activities have been described to Myrcia essential oils, while hypoglycemic, anti-hemorrhagic and antioxidant activities were attributed to the extracts. Flavonoid glucosides and acetophenone derivatives showed aldose reductase and α-glucosidase inhibition, and could explain the traditional use of Myrcia species to treat diabetes. Antimicrobial and anti-inflammatory are some of the activities observed for other isolated compounds from Myrcia. SN - 1422-0067 UR - https://www.unboundmedicine.com/medline/citation/26556334/Constituents_and_Pharmacological_Activities_of_Myrcia__Myrtaceae_:_A_Review_of_an_Aromatic_and_Medicinal_Group_of_Plants_ L2 - http://www.mdpi.com/resolver?pii=ijms161023881 DB - PRIME DP - Unbound Medicine ER -