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Cannabidiol-2',6'-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice.
J Toxicol Sci. 2015 Dec; 40(6):739-43.JT

Abstract

The biological activities of cannabidiol (CBD), a major non-psychotropic constituent of the fiber-type cannabis plant, have been examined in detail (e.g., CBD modulation of body weight in mice and rats). However, few studies have investigated the biological activities of cannabidiol-2',6'-dimethyl ether (CBDD), a dimethyl ether derivative of the parent CBD. We herein focused on the effects of CBDD on body weight changes in mice, and demonstrated that it stimulated body weight gain in apolipoprotein E (ApoE)-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice, especially between 10 and 20 weeks of age.

Authors+Show Affiliations

Department of Molecular Biology, Daiichi University of Pharmacy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26558454

Citation

Takeda, Shuso, et al. "Cannabidiol-2',6'-dimethyl Ether Stimulates Body Weight Gain in Apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) Mice." The Journal of Toxicological Sciences, vol. 40, no. 6, 2015, pp. 739-43.
Takeda S, Hirota R, Teradaira S, et al. Cannabidiol-2',6'-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice. J Toxicol Sci. 2015;40(6):739-43.
Takeda, S., Hirota, R., Teradaira, S., Takeda-Imoto, M., Watanabe, K., Toda, A., & Aramaki, H. (2015). Cannabidiol-2',6'-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice. The Journal of Toxicological Sciences, 40(6), 739-43. https://doi.org/10.2131/jts.40.739
Takeda S, et al. Cannabidiol-2',6'-dimethyl Ether Stimulates Body Weight Gain in Apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) Mice. J Toxicol Sci. 2015;40(6):739-43. PubMed PMID: 26558454.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol-2',6'-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice. AU - Takeda,Shuso, AU - Hirota,Rena, AU - Teradaira,Sari, AU - Takeda-Imoto,Masumi, AU - Watanabe,Kazuhito, AU - Toda,Akihisa, AU - Aramaki,Hironori, PY - 2015/11/13/entrez PY - 2015/11/13/pubmed PY - 2016/8/23/medline SP - 739 EP - 43 JF - The Journal of toxicological sciences JO - J Toxicol Sci VL - 40 IS - 6 N2 - The biological activities of cannabidiol (CBD), a major non-psychotropic constituent of the fiber-type cannabis plant, have been examined in detail (e.g., CBD modulation of body weight in mice and rats). However, few studies have investigated the biological activities of cannabidiol-2',6'-dimethyl ether (CBDD), a dimethyl ether derivative of the parent CBD. We herein focused on the effects of CBDD on body weight changes in mice, and demonstrated that it stimulated body weight gain in apolipoprotein E (ApoE)-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice, especially between 10 and 20 weeks of age. SN - 1880-3989 UR - https://www.unboundmedicine.com/medline/citation/26558454/Cannabidiol_2'6'_dimethyl_ether_stimulates_body_weight_gain_in_apolipoprotein_E_deficient_BALB/c__KOR/Stm_Slc_Apoe_shl__mice_ L2 - https://dx.doi.org/10.2131/jts.40.739 DB - PRIME DP - Unbound Medicine ER -