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Asthma and obesity: is weight reduction the key to achieve asthma control?
Curr Opin Pulm Med. 2016 Jan; 22(1):69-73.CO

Abstract

PURPOSE OF REVIEW

Obesity has significant negative impact on asthma control and risk of exacerbations. The purpose of this review is to discuss recent studies evaluating the effects of weight reduction on asthma control in obese adults.

RECENT FINDINGS

Clinical studies have shown that weight reduction in obese patients is associated with improvements in symptoms, use of controller medication, and asthma-related quality of life together with a reduction in the risk for severe exacerbations. Furthermore, several studies have also revealed improvements in lung function and airway responsiveness, and more recently it has been shown that weight reduction following bariatric surgery has positive impact on small airway function, systemic inflammation and bronchial inflammation in this group of patients, which may explain the observed improvements in symptom control and lung function.

SUMMARY

Weight reduction in obese adults with asthma leads to an overall improvement in asthma control, including airway hyperresponsiveness and inflammation. Weight reduction should be a cornerstone in the management of obese patients with asthma.

Authors+Show Affiliations

aDepartment of Pulmonary Medicine, Hvidovre Hospital bInstitute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26574719

Citation

Ulrik, Charlotte S.. "Asthma and Obesity: Is Weight Reduction the Key to Achieve Asthma Control?" Current Opinion in Pulmonary Medicine, vol. 22, no. 1, 2016, pp. 69-73.
Ulrik CS. Asthma and obesity: is weight reduction the key to achieve asthma control? Curr Opin Pulm Med. 2016;22(1):69-73.
Ulrik, C. S. (2016). Asthma and obesity: is weight reduction the key to achieve asthma control? Current Opinion in Pulmonary Medicine, 22(1), 69-73. https://doi.org/10.1097/MCP.0000000000000226
Ulrik CS. Asthma and Obesity: Is Weight Reduction the Key to Achieve Asthma Control. Curr Opin Pulm Med. 2016;22(1):69-73. PubMed PMID: 26574719.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asthma and obesity: is weight reduction the key to achieve asthma control? A1 - Ulrik,Charlotte S, PY - 2015/11/18/entrez PY - 2015/11/18/pubmed PY - 2016/3/8/medline SP - 69 EP - 73 JF - Current opinion in pulmonary medicine JO - Curr Opin Pulm Med VL - 22 IS - 1 N2 - PURPOSE OF REVIEW: Obesity has significant negative impact on asthma control and risk of exacerbations. The purpose of this review is to discuss recent studies evaluating the effects of weight reduction on asthma control in obese adults. RECENT FINDINGS: Clinical studies have shown that weight reduction in obese patients is associated with improvements in symptoms, use of controller medication, and asthma-related quality of life together with a reduction in the risk for severe exacerbations. Furthermore, several studies have also revealed improvements in lung function and airway responsiveness, and more recently it has been shown that weight reduction following bariatric surgery has positive impact on small airway function, systemic inflammation and bronchial inflammation in this group of patients, which may explain the observed improvements in symptom control and lung function. SUMMARY: Weight reduction in obese adults with asthma leads to an overall improvement in asthma control, including airway hyperresponsiveness and inflammation. Weight reduction should be a cornerstone in the management of obese patients with asthma. SN - 1531-6971 UR - https://www.unboundmedicine.com/medline/citation/26574719/Asthma_and_obesity:_is_weight_reduction_the_key_to_achieve_asthma_control L2 - http://dx.doi.org/10.1097/MCP.0000000000000226 DB - PRIME DP - Unbound Medicine ER -