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Consumption of nuts and risk of total and cause-specific mortality over 15 years.
Nutr Metab Cardiovasc Dis 2015; 25(12):1125-31NM

Abstract

BACKGROUND AND AIMS

The published literature shows that nut consumption has a favorable impact on health. We aimed to assess the association between nut consumption and risk of 15-year total mortality, and mortality from cardiovascular disease (CVD) (including ischemic heart disease, IHD, and stroke), and cancer.

METHODS AND RESULTS

Prospective analyses involved 2893 participants aged ≥49 years at baseline. Dietary data were collected by using a semi-quantitative food-frequency questionnaire, and nut intakes were calculated. Deaths and cause of death were confirmed by data linkage with the Australian National Death Index. Over 15 years, 1044 participants had died, of these 430 had died from stroke and another 430 had died from IHD. Participants in the second tertile of nut consumption versus those in the first tertile of intake had reduced risk of total mortality: multivariable-adjusted HR 0.76 (95% CI 0.65-0.89). Participants in the second tertile compared to those in the first tertile had 24% and 23% reduced risk of 15-year CVD and IHD mortality, respectively. Associations were more marked in women compared to men. Women in the second versus first tertile of nut consumption had 27%, 39%, 34% and 49% reduced risk of death from all causes (n = 489), CVD (n = 258), IHD (n = 188) and stroke mortality (n = 101), respectively.

CONCLUSIONS

Nut consumption was independently associated with a decreased risk of overall and vascular-disease mortality, particularly in women.

Authors+Show Affiliations

Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, The University of Sydney, Sydney, Australia. Electronic address: bamini.gopinath@sydney.edu.au.Faculty of Health Sciences, The University of Sydney, Sydney, Australia; St Vincent's Hospital, Sydney, Australia.Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, The University of Sydney, Sydney, Australia.Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, The University of Sydney, Sydney, Australia.

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26607701

Citation

Gopinath, B, et al. "Consumption of Nuts and Risk of Total and Cause-specific Mortality Over 15 Years." Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, vol. 25, no. 12, 2015, pp. 1125-31.
Gopinath B, Flood VM, Burlutksy G, et al. Consumption of nuts and risk of total and cause-specific mortality over 15 years. Nutr Metab Cardiovasc Dis. 2015;25(12):1125-31.
Gopinath, B., Flood, V. M., Burlutksy, G., & Mitchell, P. (2015). Consumption of nuts and risk of total and cause-specific mortality over 15 years. Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 25(12), pp. 1125-31. doi:10.1016/j.numecd.2015.09.006.
Gopinath B, et al. Consumption of Nuts and Risk of Total and Cause-specific Mortality Over 15 Years. Nutr Metab Cardiovasc Dis. 2015;25(12):1125-31. PubMed PMID: 26607701.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Consumption of nuts and risk of total and cause-specific mortality over 15 years. AU - Gopinath,B, AU - Flood,V M, AU - Burlutksy,G, AU - Mitchell,P, Y1 - 2015/09/25/ PY - 2015/06/25/received PY - 2015/09/08/revised PY - 2015/09/15/accepted PY - 2015/11/27/entrez PY - 2015/11/27/pubmed PY - 2016/9/23/medline KW - Blue Mountains Eye Study KW - Cardiovascular disease KW - Mortality KW - Nut consumption KW - Older adults SP - 1125 EP - 31 JF - Nutrition, metabolism, and cardiovascular diseases : NMCD JO - Nutr Metab Cardiovasc Dis VL - 25 IS - 12 N2 - BACKGROUND AND AIMS: The published literature shows that nut consumption has a favorable impact on health. We aimed to assess the association between nut consumption and risk of 15-year total mortality, and mortality from cardiovascular disease (CVD) (including ischemic heart disease, IHD, and stroke), and cancer. METHODS AND RESULTS: Prospective analyses involved 2893 participants aged ≥49 years at baseline. Dietary data were collected by using a semi-quantitative food-frequency questionnaire, and nut intakes were calculated. Deaths and cause of death were confirmed by data linkage with the Australian National Death Index. Over 15 years, 1044 participants had died, of these 430 had died from stroke and another 430 had died from IHD. Participants in the second tertile of nut consumption versus those in the first tertile of intake had reduced risk of total mortality: multivariable-adjusted HR 0.76 (95% CI 0.65-0.89). Participants in the second tertile compared to those in the first tertile had 24% and 23% reduced risk of 15-year CVD and IHD mortality, respectively. Associations were more marked in women compared to men. Women in the second versus first tertile of nut consumption had 27%, 39%, 34% and 49% reduced risk of death from all causes (n = 489), CVD (n = 258), IHD (n = 188) and stroke mortality (n = 101), respectively. CONCLUSIONS: Nut consumption was independently associated with a decreased risk of overall and vascular-disease mortality, particularly in women. SN - 1590-3729 UR - https://www.unboundmedicine.com/medline/citation/26607701/Consumption_of_nuts_and_risk_of_total_and_cause_specific_mortality_over_15_years_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0939-4753(15)30069-7 DB - PRIME DP - Unbound Medicine ER -