Shimoda, Yusuke, et al. "De Novo Arteriovenous Malformation in a Patient With Hereditary Hemorrhagic Telangiectasia." Journal of Neurosurgery. Pediatrics, vol. 17, no. 3, 2016, pp. 330-5.
Shimoda Y, Osanai T, Nakayama N, et al. De novo arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia. J Neurosurg Pediatr. 2016;17(3):330-5.
Shimoda, Y., Osanai, T., Nakayama, N., Ushikoshi, S., Hokari, M., Shichinohe, H., Abumiya, T., Kazumata, K., & Houkin, K. (2016). De novo arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia. Journal of Neurosurgery. Pediatrics, 17(3), 330-5. https://doi.org/10.3171/2015.7.PEDS15245
Shimoda Y, et al. De Novo Arteriovenous Malformation in a Patient With Hereditary Hemorrhagic Telangiectasia. J Neurosurg Pediatr. 2016;17(3):330-5. PubMed PMID: 26613274.
TY - JOUR
T1 - De novo arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia.
AU - Shimoda,Yusuke,
AU - Osanai,Toshiya,
AU - Nakayama,Naoki,
AU - Ushikoshi,Satoshi,
AU - Hokari,Masaaki,
AU - Shichinohe,Hideo,
AU - Abumiya,Takeo,
AU - Kazumata,Ken,
AU - Houkin,Kiyohiro,
Y1 - 2015/11/27/
PY - 2015/11/28/entrez
PY - 2015/11/28/pubmed
PY - 2016/7/9/medline
KW - AVM = arteriovenous malformation
KW - DSA = digital subtraction angiography
KW - HHT = hereditary hemorrhagic telangiectasia
KW - Rendu-Osler-Weber syndrome
KW - VEGF = vascular endothelial growth factor
KW - de novo arteriovenous malformation
KW - hereditary hemorrhagic telangiectasia
KW - vascular disorders
SP - 330
EP - 5
JF - Journal of neurosurgery. Pediatrics
JO - J Neurosurg Pediatr
VL - 17
IS - 3
N2 - Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant systemic disorder characterized by the enlargement of capillaries, recurrent nosebleeds, and multiple arteriovenous malformations (AVMs). Although cerebral AVMs are traditionally considered to be congenital lesions, some reports have described de novo AVMs, which suggests that the authors believed them to be dynamic conditions. In this article, the authors describe the case of a 5-year-old boy with HHT in whom a de novo cerebral AVM was detected after a negative MRI result at 5 months. To the authors' knowledge, this is the first report of a de novo AVM in a patient with HHT. In patients with a family history of HHT, de novo AVMs are possible, even when no lesions are detected at the first screening. Therefore, regular screenings need to be performed, and the family should be informed that AVMs could still develop despite normal MRI results.
SN - 1933-0715
UR - https://www.unboundmedicine.com/medline/citation/26613274/De_novo_arteriovenous_malformation_in_a_patient_with_hereditary_hemorrhagic_telangiectasia_
DB - PRIME
DP - Unbound Medicine