Tags

Type your tag names separated by a space and hit enter

Osteopenia is associated with glycemic levels and blood pressure in Chinese postmenopausal women: a cross-sectional study.
Clin Exp Med. 2017 Feb; 17(1):85-91.CE

Abstract

The aim of present study was to explore the relationships between osteopenia and dyslipidemia, glycemic levels or blood pressure in postmenopausal Chinese women. A total of 4080 women aged 42-85 years were enrolled in this cross-sectional study, which was nested in an ongoing longitudinal (REACTION) study. Calcaneus quantitative ultrasound (QUS) was performed and QUS T score was calculated to assess bone mineral density. Osteopenia was defined as a T score ≤-1.0. The relationship between osteopenia and dyslipidemia, glycemic levels or blood pressure was investigated. The prevalence of osteopenia was significantly lower in subjects with systolic blood pressure (SBP) ≥140 mmHg, fasting blood glucose (FBG) ≥8.0 mmol/L, postprandial blood glucose (PBG) ≥15.0 mmol/L, hemoglobin A1c (HbA1C) 6.5-7.5 %, HbA1C ≥7.5 %. These relationships remained significant after controlling for multiple factors. Moreover, significant trend between osteopenia and SBP, FBG, PBG and HbA1C was observed in women. In contrast, no significant associations between osteopenia and diastolic blood pressure (DBP), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) were found, and no significant trend relationship between osteopenia and DBP, TC, TG, HDL-C, LDL-C was found in postmenopausal Chinese women. The present study showed a relationship between SBP, FBG, PBG, HbA1C and osteopenia in postmenopausal Chinese women, while no significant relationship was observed between dyslipidemia, DBP and osteopenia, even after controlling for multiple confounding factors.

Authors+Show Affiliations

Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. Internal Medicine, Hospital of TCM, Fushun, 113008, Liaoning, China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. School of Medicine, Nankai University, Tianjin, 300071, China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. jianmingba@126.com.Division of Endocrinology, Department of Endocrinology, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. muyimingvip@126.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26615829

Citation

Sun, Qihong, et al. "Osteopenia Is Associated With Glycemic Levels and Blood Pressure in Chinese Postmenopausal Women: a Cross-sectional Study." Clinical and Experimental Medicine, vol. 17, no. 1, 2017, pp. 85-91.
Sun Q, Zheng Y, Chen K, et al. Osteopenia is associated with glycemic levels and blood pressure in Chinese postmenopausal women: a cross-sectional study. Clin Exp Med. 2017;17(1):85-91.
Sun, Q., Zheng, Y., Chen, K., Yan, W., Lu, J., Dou, J., Lv, Z., Wang, B., Gu, W., Ba, J., & Mu, Y. (2017). Osteopenia is associated with glycemic levels and blood pressure in Chinese postmenopausal women: a cross-sectional study. Clinical and Experimental Medicine, 17(1), 85-91. https://doi.org/10.1007/s10238-015-0397-7
Sun Q, et al. Osteopenia Is Associated With Glycemic Levels and Blood Pressure in Chinese Postmenopausal Women: a Cross-sectional Study. Clin Exp Med. 2017;17(1):85-91. PubMed PMID: 26615829.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Osteopenia is associated with glycemic levels and blood pressure in Chinese postmenopausal women: a cross-sectional study. AU - Sun,Qihong, AU - Zheng,Yu, AU - Chen,Kang, AU - Yan,Wenhua, AU - Lu,Juming, AU - Dou,Jingtao, AU - Lv,Zhaohui, AU - Wang,Baoan, AU - Gu,Weijun, AU - Ba,Jianming, AU - Mu,Yiming, Y1 - 2015/11/29/ PY - 2015/07/19/received PY - 2015/10/13/accepted PY - 2015/12/1/pubmed PY - 2017/2/9/medline PY - 2015/12/1/entrez KW - Cardiovascular diseases KW - Diabetes KW - Osteopenia KW - Quantitative ultrasound SP - 85 EP - 91 JF - Clinical and experimental medicine JO - Clin Exp Med VL - 17 IS - 1 N2 - The aim of present study was to explore the relationships between osteopenia and dyslipidemia, glycemic levels or blood pressure in postmenopausal Chinese women. A total of 4080 women aged 42-85 years were enrolled in this cross-sectional study, which was nested in an ongoing longitudinal (REACTION) study. Calcaneus quantitative ultrasound (QUS) was performed and QUS T score was calculated to assess bone mineral density. Osteopenia was defined as a T score ≤-1.0. The relationship between osteopenia and dyslipidemia, glycemic levels or blood pressure was investigated. The prevalence of osteopenia was significantly lower in subjects with systolic blood pressure (SBP) ≥140 mmHg, fasting blood glucose (FBG) ≥8.0 mmol/L, postprandial blood glucose (PBG) ≥15.0 mmol/L, hemoglobin A1c (HbA1C) 6.5-7.5 %, HbA1C ≥7.5 %. These relationships remained significant after controlling for multiple factors. Moreover, significant trend between osteopenia and SBP, FBG, PBG and HbA1C was observed in women. In contrast, no significant associations between osteopenia and diastolic blood pressure (DBP), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) were found, and no significant trend relationship between osteopenia and DBP, TC, TG, HDL-C, LDL-C was found in postmenopausal Chinese women. The present study showed a relationship between SBP, FBG, PBG, HbA1C and osteopenia in postmenopausal Chinese women, while no significant relationship was observed between dyslipidemia, DBP and osteopenia, even after controlling for multiple confounding factors. SN - 1591-9528 UR - https://www.unboundmedicine.com/medline/citation/26615829/Osteopenia_is_associated_with_glycemic_levels_and_blood_pressure_in_Chinese_postmenopausal_women:_a_cross_sectional_study_ L2 - https://dx.doi.org/10.1007/s10238-015-0397-7 DB - PRIME DP - Unbound Medicine ER -