Citation
Salinero-Fort, Miguel Ángel, et al. "Cardiovascular and All-cause Mortality in Patients With Type 2 Diabetes Mellitus in the MADIABETES Cohort Study: Association With Chronic Kidney Disease." Journal of Diabetes and Its Complications, vol. 30, no. 2, 2016, pp. 227-36.
Salinero-Fort MÁ, San Andrés-Rebollo FJ, de Burgos-Lunar C, et al. Cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus in the MADIABETES Cohort Study: Association with chronic kidney disease. J Diabetes Complications. 2016;30(2):227-36.
Salinero-Fort, M. Á., San Andrés-Rebollo, F. J., de Burgos-Lunar, C., Abánades-Herranz, J. C., Carrillo-de-Santa-Pau, E., Chico-Moraleja, R. M., Jiménez-García, R., López-de-Andrés, A., & Gómez-Campelo, P. (2016). Cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus in the MADIABETES Cohort Study: Association with chronic kidney disease. Journal of Diabetes and Its Complications, 30(2), 227-36. https://doi.org/10.1016/j.jdiacomp.2015.10.007
Salinero-Fort MÁ, et al. Cardiovascular and All-cause Mortality in Patients With Type 2 Diabetes Mellitus in the MADIABETES Cohort Study: Association With Chronic Kidney Disease. J Diabetes Complications. 2016;30(2):227-36. PubMed PMID: 26627635.
TY - JOUR
T1 - Cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus in the MADIABETES Cohort Study: Association with chronic kidney disease.
AU - Salinero-Fort,Miguel Ángel,
AU - San Andrés-Rebollo,Francisco Javier,
AU - de Burgos-Lunar,Carmen,
AU - Abánades-Herranz,Juan Carlos,
AU - Carrillo-de-Santa-Pau,Enrique,
AU - Chico-Moraleja,Rosa María,
AU - Jiménez-García,Rodrigo,
AU - López-de-Andrés,Ana,
AU - Gómez-Campelo,Paloma,
AU - ,,
Y1 - 2015/10/21/
PY - 2015/07/07/received
PY - 2015/09/30/revised
PY - 2015/10/14/accepted
PY - 2015/12/3/entrez
PY - 2015/12/3/pubmed
PY - 2016/12/15/medline
KW - Cohort studies
KW - Diabetes complications
KW - Diabetes mellitus, type 2
KW - Kidney diseases
KW - Mortality
SP - 227
EP - 36
JF - Journal of diabetes and its complications
JO - J Diabetes Complications
VL - 30
IS - 2
N2 - AIMS: To assess the prevalence of stage 3-5 chronic kidney disease (CKD) at baseline and to identify associated risk factors. To determine the effect of CKD and CKD stage according to estimated glomerular filtration rate (eGFR) and albuminuria categories on all-cause and cardiovascular mortality after a 5-year follow-up. METHODS: Prospective cohort study of 3443 outpatients with type 2 diabetes mellitus. RESULTS: The prevalence of CKD was 28.32% (95% CI, 26.84-29.86); and variables most strongly associated were: age >74 years (OR, 19.88; 95% CI, 12.89-30.68) and albuminuria (OR, 2.27; 95% CI, 1.72-3.00). During follow-up, 221 CKD patients (22.90%) died compared with 203 non-CKD patients (8.31%) (p<0.01). The adjusted HR of CKD for cardiovascular and all-cause mortality was 1.82 (95% CI, 1.36-2.44) and 2.11 (95% CI, 1.61-2.76) for those with LDL cholesterol =135 mg/dl, respectively. The adjusted HR of very-high-risk CKD for all-cause mortality was 4.44 (95% CI, 2.31-8.53) in aged <75 years and 1.80 (95% CI, 1.19-2.72) in aged ≥75 years. CONCLUSIONS: CKD at baseline is an independent risk factor for all-cause and cardiovascular mortality in the overall cohort, men and women, or in primary and secondary prevention of coronary heart disease. Albuminuria is an independent risk factor for all-cause and cardiovascular mortality only in primary prevention.
SN - 1873-460X
UR - https://www.unboundmedicine.com/medline/citation/26627635/Cardiovascular_and_all_cause_mortality_in_patients_with_type_2_diabetes_mellitus_in_the_MADIABETES_Cohort_Study:_Association_with_chronic_kidney_disease_
DB - PRIME
DP - Unbound Medicine
ER -
