Tags

Type your tag names separated by a space and hit enter

Increased frequency of HLA B8 in hyperostotic spondylosis.
J Rheumatol Suppl. 1977; 3:94-6.JR

Abstract

HLA antigens were determined in 50 patients with hyperostotic spondylosis (Forestier's disease), and compared with 1244 normal controls. There was no significant difference in the distribution of HLA B27 between the two groups. However, there was an increased incidence of HLA B8 among the patients with hyperostotic spondylosis (42 per cent), as compared to the normal controls (17.5 per cent). This difference was statistically significant (p less than 0.005). Sixteen of the 50 patients with hyperostotic spondylosis had evidence of diabetes mellitus, 12 of whom also had the HLA B8 antigen. Thus patients with hyperostotic spondylosis have an increased incidence of HLA B8, associated with an increased incidence of diabetes mellitus.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

266608

Citation

Rosenthal, M, et al. "Increased Frequency of HLA B8 in Hyperostotic Spondylosis." The Journal of Rheumatology. Supplement, vol. 3, 1977, pp. 94-6.
Rosenthal M, Bahous I, Muller W. Increased frequency of HLA B8 in hyperostotic spondylosis. J Rheumatol Suppl. 1977;3:94-6.
Rosenthal, M., Bahous, I., & Muller, W. (1977). Increased frequency of HLA B8 in hyperostotic spondylosis. The Journal of Rheumatology. Supplement, 3, 94-6.
Rosenthal M, Bahous I, Muller W. Increased Frequency of HLA B8 in Hyperostotic Spondylosis. J Rheumatol Suppl. 1977;3:94-6. PubMed PMID: 266608.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased frequency of HLA B8 in hyperostotic spondylosis. AU - Rosenthal,M, AU - Bahous,I, AU - Muller,W, PY - 1977/1/1/pubmed PY - 1977/1/1/medline PY - 1977/1/1/entrez SP - 94 EP - 6 JF - The Journal of rheumatology. Supplement JO - J Rheumatol Suppl VL - 3 N2 - HLA antigens were determined in 50 patients with hyperostotic spondylosis (Forestier's disease), and compared with 1244 normal controls. There was no significant difference in the distribution of HLA B27 between the two groups. However, there was an increased incidence of HLA B8 among the patients with hyperostotic spondylosis (42 per cent), as compared to the normal controls (17.5 per cent). This difference was statistically significant (p less than 0.005). Sixteen of the 50 patients with hyperostotic spondylosis had evidence of diabetes mellitus, 12 of whom also had the HLA B8 antigen. Thus patients with hyperostotic spondylosis have an increased incidence of HLA B8, associated with an increased incidence of diabetes mellitus. SN - 0380-0903 UR - https://www.unboundmedicine.com/medline/citation/266608/Increased_frequency_of_HLA_B8_in_hyperostotic_spondylosis_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-DPB1-2 DB - PRIME DP - Unbound Medicine ER -