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Two cases of cutaneous leishmaniasis in Dutch military personnel treated with oral miltefosine.
J R Army Med Corps. 2017 Feb; 163(1):68-70.JR

Abstract

INTRODUCTION

In the Netherlands, cutaneous leishmaniasis is most commonly seen in military personnel deployed on a mission or training abroad. The treatment of two Dutch soldiers who acquired cutaneous leishmaniasis with oral miltefosine was evaluated. Adverse effects were monitored and the improvement of skin lesions was assessed.

CASE REPORTS

A military nurse with a painless Chiclero's ulcer due to Leishmania (Viannia) braziliensis acquired in Belize and a military physical training instructor with itchy swelling and small ulcer of the back of his left elbow due to L. donovani/infantum complex acquired in Ibiza were treated with oral miltefosine 50 mg three times a day for 28 days.

DISCUSSION

Both patients responded well to oral miltefosine. Adverse effects were mild. Increase of creatinine levels was seen while liver transaminase levels were unremarkable.

CONCLUSIONS

Miltefosine proved to be a convenient, effective and well-tolerated treatment option in the treatment of cutaneous leishmaniasis in Dutch military personnel.

Authors+Show Affiliations

Department of Dermatology, Central Military Hospital, Utrecht, The Netherlands.Department of Dermatology, Central Military Hospital, Utrecht, The Netherlands.Center for Tropical and Travel Medicine, Academic Medical Center, Amsterdam, The Netherlands.Laboratory for Infectious Diseases and Perinatal Screening, RIVM, Bilthoven, The Netherlands.Department of Internal Medicine, Central Military Hospital, Utrecht, The Netherlands.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

26661280

Citation

van der Snoek, Eric Martin, et al. "Two Cases of Cutaneous Leishmaniasis in Dutch Military Personnel Treated With Oral Miltefosine." Journal of the Royal Army Medical Corps, vol. 163, no. 1, 2017, pp. 68-70.
van der Snoek EM, Couwenberg SM, Stijnis C, et al. Two cases of cutaneous leishmaniasis in Dutch military personnel treated with oral miltefosine. J R Army Med Corps. 2017;163(1):68-70.
van der Snoek, E. M., Couwenberg, S. M., Stijnis, C., Kortbeek, L. M., & Schadd, E. M. (2017). Two cases of cutaneous leishmaniasis in Dutch military personnel treated with oral miltefosine. Journal of the Royal Army Medical Corps, 163(1), 68-70. https://doi.org/10.1136/jramc-2015-000530
van der Snoek EM, et al. Two Cases of Cutaneous Leishmaniasis in Dutch Military Personnel Treated With Oral Miltefosine. J R Army Med Corps. 2017;163(1):68-70. PubMed PMID: 26661280.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Two cases of cutaneous leishmaniasis in Dutch military personnel treated with oral miltefosine. AU - van der Snoek,Eric Martin, AU - Couwenberg,S M, AU - Stijnis,C, AU - Kortbeek,L M, AU - Schadd,E M, Y1 - 2015/12/09/ PY - 2015/07/24/received PY - 2015/11/10/accepted PY - 2015/12/15/pubmed PY - 2017/6/21/medline PY - 2015/12/15/entrez KW - TROPICAL MEDICINE SP - 68 EP - 70 JF - Journal of the Royal Army Medical Corps JO - J R Army Med Corps VL - 163 IS - 1 N2 - INTRODUCTION: In the Netherlands, cutaneous leishmaniasis is most commonly seen in military personnel deployed on a mission or training abroad. The treatment of two Dutch soldiers who acquired cutaneous leishmaniasis with oral miltefosine was evaluated. Adverse effects were monitored and the improvement of skin lesions was assessed. CASE REPORTS: A military nurse with a painless Chiclero's ulcer due to Leishmania (Viannia) braziliensis acquired in Belize and a military physical training instructor with itchy swelling and small ulcer of the back of his left elbow due to L. donovani/infantum complex acquired in Ibiza were treated with oral miltefosine 50 mg three times a day for 28 days. DISCUSSION: Both patients responded well to oral miltefosine. Adverse effects were mild. Increase of creatinine levels was seen while liver transaminase levels were unremarkable. CONCLUSIONS: Miltefosine proved to be a convenient, effective and well-tolerated treatment option in the treatment of cutaneous leishmaniasis in Dutch military personnel. SN - 0035-8665 UR - https://www.unboundmedicine.com/medline/citation/26661280/Two_cases_of_cutaneous_leishmaniasis_in_Dutch_military_personnel_treated_with_oral_miltefosine_ L2 - https://militaryhealth.bmj.com/lookup/pmidlookup?view=long&pmid=26661280 DB - PRIME DP - Unbound Medicine ER -