Tags

Type your tag names separated by a space and hit enter

Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province.
Int J Legal Med. 2016 May; 130(3):689-91.IJ

Abstract

In this study, we investigated the genetic polymorphisms of 24 Y-chromosomal short tandem repeat (Y-STR) loci in 885 unrelated Chinese Han male individuals from Guangdong Province, using a domestic AGCU Y24 STR kit. A total of 878 different haplotypes were observed at the 24 Y-STR loci; among them, 871 haplotypes were unique and 7 haplotypes occurred twice. The overall haplotype diversity was 0.99998 and the discrimination capacity was 99.2%. The gene diversity values ranged from 0.4354 at DYS438 to 0.9606 at DYS385a/b. Population relationships between the Guangdong Han population and seven other published Chinese populations were evaluated by Rst values and visualized in a two multi-dimensional scaling plot. The results showed the 24 Y-STR loci are highly polymorphic in Guangdong Han population and of great value in forensic application.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Wang Y
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Liu C
Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, 510030, People's Republic of China. Guangzhou Institute for Criminal Science and Technology, Guangzhou, 510030, People's Republic of China.
Zhang CC
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Li R
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Liu H
Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, 510030, People's Republic of China. Guangzhou Institute for Criminal Science and Technology, Guangzhou, 510030, People's Republic of China.
Ou XL
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Li HX
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
Sun HY
Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China. sunhy@mail.sysu.edu.cn.

MeSH

Asian PeopleChinaChromosomes, Human, YDNA FingerprintingEthnicityGenetics, PopulationHaplotypesHumansMaleMicrosatellite RepeatsPolymerase Chain ReactionPolymorphism, Genetic

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26668007

Citation

Wang, Ying, et al. "Analysis of 24 Y-STR Haplotype Data in a Chinese Han Population From Guangdong Province." International Journal of Legal Medicine, vol. 130, no. 3, 2016, pp. 689-91.
Wang Y, Liu C, Zhang CC, et al. Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province. Int J Legal Med. 2016;130(3):689-91.
Wang, Y., Liu, C., Zhang, C. C., Li, R., Liu, H., Ou, X. L., Li, H. X., & Sun, H. Y. (2016). Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province. International Journal of Legal Medicine, 130(3), 689-91. https://doi.org/10.1007/s00414-015-1301-4
Wang Y, et al. Analysis of 24 Y-STR Haplotype Data in a Chinese Han Population From Guangdong Province. Int J Legal Med. 2016;130(3):689-91. PubMed PMID: 26668007.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province. AU - Wang,Ying, AU - Liu,Chao, AU - Zhang,Chu-chu, AU - Li,Ran, AU - Liu,Hong, AU - Ou,Xue-ling, AU - Li,Hai-xia, AU - Sun,Hong-yu, Y1 - 2015/12/14/ PY - 2015/10/08/received PY - 2015/11/27/accepted PY - 2015/12/16/entrez PY - 2015/12/17/pubmed PY - 2017/1/11/medline KW - AGCU Y24 STR KW - Guangdong Han population KW - Haplotype SP - 689 EP - 91 JF - International journal of legal medicine JO - Int J Legal Med VL - 130 IS - 3 N2 - In this study, we investigated the genetic polymorphisms of 24 Y-chromosomal short tandem repeat (Y-STR) loci in 885 unrelated Chinese Han male individuals from Guangdong Province, using a domestic AGCU Y24 STR kit. A total of 878 different haplotypes were observed at the 24 Y-STR loci; among them, 871 haplotypes were unique and 7 haplotypes occurred twice. The overall haplotype diversity was 0.99998 and the discrimination capacity was 99.2%. The gene diversity values ranged from 0.4354 at DYS438 to 0.9606 at DYS385a/b. Population relationships between the Guangdong Han population and seven other published Chinese populations were evaluated by Rst values and visualized in a two multi-dimensional scaling plot. The results showed the 24 Y-STR loci are highly polymorphic in Guangdong Han population and of great value in forensic application. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/26668007/Analysis_of_24_Y_STR_haplotype_data_in_a_Chinese_Han_population_from_Guangdong_Province_ DB - PRIME DP - Unbound Medicine ER -