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Convalescent plasma: new evidence for an old therapeutic tool?
Blood Transfus. 2016 Mar; 14(2):152-7.BT

Abstract

Passive immunisation for the prevention and treatment of human infectious diseases can be traced back to the 20(th) century. The recent Ebola virus outbreak in West Africa has turned the spotlight onto the possible use of convalescent whole blood and convalescent plasma in the treatment of infectious diseases because they are the only therapeutic strategy available in some cases, given the unavailability of vaccines, drugs or other specific treatments. Convalescent blood products could be a valid option in the treatment/prophylaxis of several infectious diseases both in association with other drugs/preventive measures and as the only therapy when a specific treatment is not available. However, there are still some issues to consider in determining the advisability of implementing a large-scale convalescent plasma transfusion programme.

Authors+Show Affiliations

Italian National Blood Centre, National Institute of Health, Rome, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy. Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, Rome, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy. Immunohaemathology and Transfusion Medicine Unit, Azienda Ospedaliera "Città della Salute e della Scienza", Turin, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy.Italian National Blood Centre, National Institute of Health, Rome, Italy.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26674811

Citation

Marano, Giuseppe, et al. "Convalescent Plasma: New Evidence for an Old Therapeutic Tool?" Blood Transfusion = Trasfusione Del Sangue, vol. 14, no. 2, 2016, pp. 152-7.
Marano G, Vaglio S, Pupella S, et al. Convalescent plasma: new evidence for an old therapeutic tool? Blood Transfus. 2016;14(2):152-7.
Marano, G., Vaglio, S., Pupella, S., Facco, G., Catalano, L., Liumbruno, G. M., & Grazzini, G. (2016). Convalescent plasma: new evidence for an old therapeutic tool? Blood Transfusion = Trasfusione Del Sangue, 14(2), 152-7. https://doi.org/10.2450/2015.0131-15
Marano G, et al. Convalescent Plasma: New Evidence for an Old Therapeutic Tool. Blood Transfus. 2016;14(2):152-7. PubMed PMID: 26674811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Convalescent plasma: new evidence for an old therapeutic tool? AU - Marano,Giuseppe, AU - Vaglio,Stefania, AU - Pupella,Simonetta, AU - Facco,Giuseppina, AU - Catalano,Liviana, AU - Liumbruno,Giancarlo M, AU - Grazzini,Giuliano, Y1 - 2015/11/06/ PY - 2015/05/22/received PY - 2015/07/23/accepted PY - 2015/12/18/entrez PY - 2015/12/18/pubmed PY - 2016/12/15/medline SP - 152 EP - 7 JF - Blood transfusion = Trasfusione del sangue JO - Blood Transfus VL - 14 IS - 2 N2 - Passive immunisation for the prevention and treatment of human infectious diseases can be traced back to the 20(th) century. The recent Ebola virus outbreak in West Africa has turned the spotlight onto the possible use of convalescent whole blood and convalescent plasma in the treatment of infectious diseases because they are the only therapeutic strategy available in some cases, given the unavailability of vaccines, drugs or other specific treatments. Convalescent blood products could be a valid option in the treatment/prophylaxis of several infectious diseases both in association with other drugs/preventive measures and as the only therapy when a specific treatment is not available. However, there are still some issues to consider in determining the advisability of implementing a large-scale convalescent plasma transfusion programme. SN - 2385-2070 UR - https://www.unboundmedicine.com/medline/citation/26674811/full_citation L2 - https://doi.org/10.2450/2015.0131-15 DB - PRIME DP - Unbound Medicine ER -