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Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes.
Rev Soc Bras Med Trop. 2015 Nov-Dec; 48(6):746-52.RS

Abstract

INTRODUCTION

In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507.

METHODS

Morphological changes in these fungi after treatment with the oil were determined by scanning electron microscopy (SEM). The antifungal activity of the oil was determined on the basis of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values.

RESULTS

The compound 1,8-cineole was found to be the predominant component (72.2%) of the essential oil. The MIC values of the oil ranged from 62.5μg·mL-1 to >1,000μg·mL-1, and the MFC values of the oil ranged from 125μg·mL-1 to >1,000μg·mL-1. SEM analysis showed physical damage and morphological alterations in the fungi exposed to this oil.

CONCLUSIONS

We demonstrated the potential of Eucalyptus smithii essential oil as a natural therapeutic agent for the treatment of dermatophytosis.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Baptista EB
Núcleo de Pesquisa e Inovação em Ciências da Saúde, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Zimmermann-Franco DC
Núcleo de Pesquisa e Inovação em Ciências da Saúde, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Lataliza AA
Núcleo de Pesquisa e Inovação em Ciências da Saúde, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Raposo NR
Núcleo de Pesquisa e Inovação em Ciências da Saúde, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

MeSH

Antifungal AgentsEucalyptusMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMicrosporumOils, VolatilePlant ExtractsTrichophyton

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26676500

Citation

Baptista, Edilene Bolutari, et al. "Chemical Composition and Antifungal Activity of Essential Oil From Eucalyptus Smithii Against Dermatophytes." Revista Da Sociedade Brasileira De Medicina Tropical, vol. 48, no. 6, 2015, pp. 746-52.
Baptista EB, Zimmermann-Franco DC, Lataliza AA, et al. Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes. Rev Soc Bras Med Trop. 2015;48(6):746-52.
Baptista, E. B., Zimmermann-Franco, D. C., Lataliza, A. A., & Raposo, N. R. (2015). Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes. Revista Da Sociedade Brasileira De Medicina Tropical, 48(6), 746-52. https://doi.org/10.1590/0037-8682-0188-2015
Baptista EB, et al. Chemical Composition and Antifungal Activity of Essential Oil From Eucalyptus Smithii Against Dermatophytes. Rev Soc Bras Med Trop. 2015 Nov-Dec;48(6):746-52. PubMed PMID: 26676500.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes. AU - Baptista,Edilene Bolutari, AU - Zimmermann-Franco,Danielle Cristina, AU - Lataliza,Alexandre Augusto Barros, AU - Raposo,Nádia Rezende Barbosa, PY - 2015/06/22/received PY - 2015/09/08/accepted PY - 2015/12/18/entrez PY - 2015/12/18/pubmed PY - 2016/5/25/medline SP - 746 EP - 52 JF - Revista da Sociedade Brasileira de Medicina Tropical JO - Rev Soc Bras Med Trop VL - 48 IS - 6 N2 - INTRODUCTION: In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507. METHODS: Morphological changes in these fungi after treatment with the oil were determined by scanning electron microscopy (SEM). The antifungal activity of the oil was determined on the basis of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values. RESULTS: The compound 1,8-cineole was found to be the predominant component (72.2%) of the essential oil. The MIC values of the oil ranged from 62.5μg·mL-1 to >1,000μg·mL-1, and the MFC values of the oil ranged from 125μg·mL-1 to >1,000μg·mL-1. SEM analysis showed physical damage and morphological alterations in the fungi exposed to this oil. CONCLUSIONS: We demonstrated the potential of Eucalyptus smithii essential oil as a natural therapeutic agent for the treatment of dermatophytosis. SN - 1678-9849 UR - https://www.unboundmedicine.com/medline/citation/26676500/Chemical_composition_and_antifungal_activity_of_essential_oil_from_Eucalyptus_smithii_against_dermatophytes_ DB - PRIME DP - Unbound Medicine ER -