Tags

Type your tag names separated by a space and hit enter

Association between nut consumption and coronary heart disease: a meta-analysis.
Coron Artery Dis 2016; 27(3):227-32CA

Abstract

OBJECTIVES

Epidemiological studies evaluating the association of nut consumption with coronary heart disease (CHD) risk have produced inconsistent results. The current study aimed to assess the CHD risk for the highest versus the lowest categories of nut consumption, the dose-response association of CHD for every 1 serving/week increment in nut consumption, and the heterogeneity among studies and publication bias.

METHODS

Pertinent studies were identified by a search in PubMed and Web of Knowledge up to January 2014. A random-effect model was used to combine the results. The dose-response relationship was assessed by restricted cubic spline and variance-weighted least squares regression analysis. Publication bias was estimated using Egger's regression asymmetry test.

RESULTS

Ten articles with 14 studies including 6302 CHD cases were included in this meta-analysis. Pooled results suggested that highest nut consumption amount versus lowest amount was associated significantly with a reduced risk of CHD [summary relative risk (RR)=0.681, 95% confidence interval (CI)=0.592-0.783, I(2)=62.7%], especially among USA (summary RR=0.671, 95% CI=0.591-0.761) and prospective studies (summary RR=0.660, 95% CI=0.581-0.748). A linear dose-response relationship was found, and the risk of CHD decreased by 10% for every 1 serving/week increase intake of nut (summary RR=0.90, 95% CI=0.87-0.94) No publication bias was found.

CONCLUSION

Our analysis suggested that higher nut consumption might have a protective effect on CHD risk, especially in the USA, which needs to be confirmed.

Authors+Show Affiliations

Department of Emergency Medicine, Affiliated Hospital of Medical College, Qingdao University, Qingdao, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Review

Language

eng

PubMed ID

26704188

Citation

Weng, Yun-Qi, et al. "Association Between Nut Consumption and Coronary Heart Disease: a Meta-analysis." Coronary Artery Disease, vol. 27, no. 3, 2016, pp. 227-32.
Weng YQ, Yao J, Guo ML, et al. Association between nut consumption and coronary heart disease: a meta-analysis. Coron Artery Dis. 2016;27(3):227-32.
Weng, Y. Q., Yao, J., Guo, M. L., Qin, Q. J., & Li, P. (2016). Association between nut consumption and coronary heart disease: a meta-analysis. Coronary Artery Disease, 27(3), pp. 227-32. doi:10.1097/MCA.0000000000000331.
Weng YQ, et al. Association Between Nut Consumption and Coronary Heart Disease: a Meta-analysis. Coron Artery Dis. 2016;27(3):227-32. PubMed PMID: 26704188.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association between nut consumption and coronary heart disease: a meta-analysis. AU - Weng,Yun-Qi, AU - Yao,Jian, AU - Guo,Ming-Lei, AU - Qin,Qiao-Ji, AU - Li,Peng, PY - 2015/12/26/entrez PY - 2015/12/26/pubmed PY - 2017/1/18/medline SP - 227 EP - 32 JF - Coronary artery disease JO - Coron. Artery Dis. VL - 27 IS - 3 N2 - OBJECTIVES: Epidemiological studies evaluating the association of nut consumption with coronary heart disease (CHD) risk have produced inconsistent results. The current study aimed to assess the CHD risk for the highest versus the lowest categories of nut consumption, the dose-response association of CHD for every 1 serving/week increment in nut consumption, and the heterogeneity among studies and publication bias. METHODS: Pertinent studies were identified by a search in PubMed and Web of Knowledge up to January 2014. A random-effect model was used to combine the results. The dose-response relationship was assessed by restricted cubic spline and variance-weighted least squares regression analysis. Publication bias was estimated using Egger's regression asymmetry test. RESULTS: Ten articles with 14 studies including 6302 CHD cases were included in this meta-analysis. Pooled results suggested that highest nut consumption amount versus lowest amount was associated significantly with a reduced risk of CHD [summary relative risk (RR)=0.681, 95% confidence interval (CI)=0.592-0.783, I(2)=62.7%], especially among USA (summary RR=0.671, 95% CI=0.591-0.761) and prospective studies (summary RR=0.660, 95% CI=0.581-0.748). A linear dose-response relationship was found, and the risk of CHD decreased by 10% for every 1 serving/week increase intake of nut (summary RR=0.90, 95% CI=0.87-0.94) No publication bias was found. CONCLUSION: Our analysis suggested that higher nut consumption might have a protective effect on CHD risk, especially in the USA, which needs to be confirmed. SN - 1473-5830 UR - https://www.unboundmedicine.com/medline/citation/26704188/Association_between_nut_consumption_and_coronary_heart_disease:_a_meta_analysis_ L2 - http://Insights.ovid.com/pubmed?pmid=26704188 DB - PRIME DP - Unbound Medicine ER -