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Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder.
Psychiatry Res. 2016 Feb 28; 236:142-147.PR

Abstract

Previous studies have shown that various factors, such as genetic and environmental factors, contribute to the development of major depressive disorder (MDD). The aim of this study is to clarify how multiple factors, including affective temperaments, childhood abuse and adult life events, are involved in the severity of depressive symptoms in MDD. A total of 98 participants with MDD were studied using the following self-administered questionnaire surveys: Patient Health Questionnaire-9 measuring the severity of depressive symptoms; Life Experiences Survey (LES) measuring negative and positive adult life events; Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego auto-questionnaire (TEMPS-A) measuring affective temperaments; and the Child Abuse and Trauma Scale (CATS) measuring childhood abuse. The data were analyzed using single and multiple regression analyses and structural equation modeling (SEM). The neglect score reported by CATS indirectly predicted the severity of depressive symptoms through affective temperaments measured by TEMPS-A in SEM. Four temperaments (depressive, cyclothymic, irritable, and anxious) directly predicted the severity of depressive symptoms. The negative change in the LES score also directly predicted severity. This study suggests that childhood abuse, especially neglect, indirectly increases the severity of depressive symptoms through increased scores of affective temperaments in MDD.

Authors+Show Affiliations

Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan. Electronic address: toda1973@ndmc.ac.jp.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan; Department of Psychiatry, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. Electronic address: tinoue@tokyo-med.ac.jp.Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan.Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan.Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan.Department of Psychiatry, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan.Department of Psychiatry, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.Department of Clinical Human Sciences, Graduate School of Humanities and Social Sciences, Shizuoka University, 836 Ohya Suruga-ku, Shizuoka 422-8529, Japan.Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan.Department of Psychiatry, National Defense Medical College, Namiki3-2, Tokorozawa, Saitama 359-8513, Japan.Department of Psychiatry, Hokkaido University Graduate School of Medicine, North15, West7, Kita-ku, Sapporo 060-8638, Japan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26708440

Citation

Toda, Hiroyuki, et al. "Affective Temperaments Play an Important Role in the Relationship Between Childhood Abuse and Depressive Symptoms in Major Depressive Disorder." Psychiatry Research, vol. 236, 2016, pp. 142-147.
Toda H, Inoue T, Tsunoda T, et al. Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder. Psychiatry Res. 2016;236:142-147.
Toda, H., Inoue, T., Tsunoda, T., Nakai, Y., Tanichi, M., Tanaka, T., Hashimoto, N., Takaesu, Y., Nakagawa, S., Kitaichi, Y., Boku, S., Tanabe, H., Nibuya, M., Yoshino, A., & Kusumi, I. (2016). Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder. Psychiatry Research, 236, 142-147. https://doi.org/10.1016/j.psychres.2015.12.016
Toda H, et al. Affective Temperaments Play an Important Role in the Relationship Between Childhood Abuse and Depressive Symptoms in Major Depressive Disorder. Psychiatry Res. 2016 Feb 28;236:142-147. PubMed PMID: 26708440.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder. AU - Toda,Hiroyuki, AU - Inoue,Takeshi, AU - Tsunoda,Tomoya, AU - Nakai,Yukiei, AU - Tanichi,Masaaki, AU - Tanaka,Teppei, AU - Hashimoto,Naoki, AU - Takaesu,Yoshikazu, AU - Nakagawa,Shin, AU - Kitaichi,Yuji, AU - Boku,Shuken, AU - Tanabe,Hajime, AU - Nibuya,Masashi, AU - Yoshino,Aihide, AU - Kusumi,Ichiro, Y1 - 2015/12/18/ PY - 2015/09/10/received PY - 2015/11/14/revised PY - 2015/12/14/accepted PY - 2015/12/29/entrez PY - 2015/12/29/pubmed PY - 2016/10/12/medline KW - Affective temperament KW - Early life stress KW - Neglect KW - Stressful life event KW - Structural equation model KW - TEMPS-A SP - 142 EP - 147 JF - Psychiatry research JO - Psychiatry Res VL - 236 N2 - Previous studies have shown that various factors, such as genetic and environmental factors, contribute to the development of major depressive disorder (MDD). The aim of this study is to clarify how multiple factors, including affective temperaments, childhood abuse and adult life events, are involved in the severity of depressive symptoms in MDD. A total of 98 participants with MDD were studied using the following self-administered questionnaire surveys: Patient Health Questionnaire-9 measuring the severity of depressive symptoms; Life Experiences Survey (LES) measuring negative and positive adult life events; Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego auto-questionnaire (TEMPS-A) measuring affective temperaments; and the Child Abuse and Trauma Scale (CATS) measuring childhood abuse. The data were analyzed using single and multiple regression analyses and structural equation modeling (SEM). The neglect score reported by CATS indirectly predicted the severity of depressive symptoms through affective temperaments measured by TEMPS-A in SEM. Four temperaments (depressive, cyclothymic, irritable, and anxious) directly predicted the severity of depressive symptoms. The negative change in the LES score also directly predicted severity. This study suggests that childhood abuse, especially neglect, indirectly increases the severity of depressive symptoms through increased scores of affective temperaments in MDD. SN - 1872-7123 UR - https://www.unboundmedicine.com/medline/citation/26708440/Affective_temperaments_play_an_important_role_in_the_relationship_between_childhood_abuse_and_depressive_symptoms_in_major_depressive_disorder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(15)30317-6 DB - PRIME DP - Unbound Medicine ER -