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Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies.
Arch Cardiovasc Dis 2016; 109(1):39-54AC

Abstract

BACKGROUND

Accumulating evidence supports health benefits of dietary fibre, such as improving lipid profiles, lowering blood pressure and improving insulin sensitivity, but evidence from comprehensive investigation of dietary fibre intake and mortality from cardiovascular disease (CVD) and all cancers is limited.

AIMS

To quantitatively assess the association between dietary fibre intake and mortality from CVD and all cancers.

METHODS

We performed a meta-analysis of prospective cohort studies. Eligible studies were identified by searching PubMed and Embase databases for all articles published up to September 2014 and via hand searching. Study-specific estimates adjusting for potential confounders were combined to calculate pooled relative risks (RRs) with 95% confidence intervals (CIs), using a random-effects model.

RESULTS

We found 15 studies that examined the association between dietary fibre and mortality from CVD, coronary heart disease (CHD) and all cancers. The pooled RRs of CVD, CHD and all-cancer mortality for the highest versus lowest category of dietary fibre were 0.77 (95% CI: 0.71-0.84), 0.76 (95% CI: 0.67-0.87) and 0.86 (95% CI: 0.79-0.93), respectively. In a dose-response meta-analysis, the pooled RRs for an increment of 10 g/day in dietary fibre intake were 0.91 (95% CI: 0.88-0.94) for CVD, 0.89 (95% CI: 0.85-0.93) for CHD and 0.94 (95% CI: 0.91-0.97) for all cancers.

CONCLUSIONS

Our findings suggest that high dietary fibre intake is associated with a reduced risk of mortality from CVD and all cancers. These results support the current recommendation that high dietary fibre intake should be part of a healthy diet.

Authors+Show Affiliations

Department of food and nutrition, Kyung Hee university, 26, Kyunghee-daero, Dongdaemun-gu, 130-701 Seoul, South Korea.Department of food and nutrition, Kyung Hee university, 26, Kyunghee-daero, Dongdaemun-gu, 130-701 Seoul, South Korea. Electronic address: youjinje@khu.ac.kr.

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

26711548

Citation

Kim, Youngyo, and Youjin Je. "Dietary Fibre Intake and Mortality From Cardiovascular Disease and All Cancers: a Meta-analysis of Prospective Cohort Studies." Archives of Cardiovascular Diseases, vol. 109, no. 1, 2016, pp. 39-54.
Kim Y, Je Y. Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies. Arch Cardiovasc Dis. 2016;109(1):39-54.
Kim, Y., & Je, Y. (2016). Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies. Archives of Cardiovascular Diseases, 109(1), pp. 39-54. doi:10.1016/j.acvd.2015.09.005.
Kim Y, Je Y. Dietary Fibre Intake and Mortality From Cardiovascular Disease and All Cancers: a Meta-analysis of Prospective Cohort Studies. Arch Cardiovasc Dis. 2016;109(1):39-54. PubMed PMID: 26711548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies. AU - Kim,Youngyo, AU - Je,Youjin, Y1 - 2015/12/18/ PY - 2015/05/27/received PY - 2015/08/31/revised PY - 2015/09/01/accepted PY - 2015/12/30/entrez PY - 2015/12/30/pubmed PY - 2016/12/16/medline KW - Cardiovascular disease KW - Fibre KW - Fibres KW - Maladies cardiovasculaires KW - Meta-analysis KW - Mortality KW - Mortalité KW - Méta-analyses KW - Prospective cohort studies KW - Étude de cohortes prospectives SP - 39 EP - 54 JF - Archives of cardiovascular diseases JO - Arch Cardiovasc Dis VL - 109 IS - 1 N2 - BACKGROUND: Accumulating evidence supports health benefits of dietary fibre, such as improving lipid profiles, lowering blood pressure and improving insulin sensitivity, but evidence from comprehensive investigation of dietary fibre intake and mortality from cardiovascular disease (CVD) and all cancers is limited. AIMS: To quantitatively assess the association between dietary fibre intake and mortality from CVD and all cancers. METHODS: We performed a meta-analysis of prospective cohort studies. Eligible studies were identified by searching PubMed and Embase databases for all articles published up to September 2014 and via hand searching. Study-specific estimates adjusting for potential confounders were combined to calculate pooled relative risks (RRs) with 95% confidence intervals (CIs), using a random-effects model. RESULTS: We found 15 studies that examined the association between dietary fibre and mortality from CVD, coronary heart disease (CHD) and all cancers. The pooled RRs of CVD, CHD and all-cancer mortality for the highest versus lowest category of dietary fibre were 0.77 (95% CI: 0.71-0.84), 0.76 (95% CI: 0.67-0.87) and 0.86 (95% CI: 0.79-0.93), respectively. In a dose-response meta-analysis, the pooled RRs for an increment of 10 g/day in dietary fibre intake were 0.91 (95% CI: 0.88-0.94) for CVD, 0.89 (95% CI: 0.85-0.93) for CHD and 0.94 (95% CI: 0.91-0.97) for all cancers. CONCLUSIONS: Our findings suggest that high dietary fibre intake is associated with a reduced risk of mortality from CVD and all cancers. These results support the current recommendation that high dietary fibre intake should be part of a healthy diet. SN - 1875-2128 UR - https://www.unboundmedicine.com/medline/citation/26711548/Dietary_fibre_intake_and_mortality_from_cardiovascular_disease_and_all_cancers:_A_meta_analysis_of_prospective_cohort_studies_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1875-2136(15)00178-3 DB - PRIME DP - Unbound Medicine ER -