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Modulation of the inter-hemispheric processing of semantic information during normal aging. A divided visual field experiment.
Neuropsychologia. 2016 Dec; 93(Pt B):425-436.N

Abstract

We evaluated the effect of normal aging on the inter-hemispheric processing of semantic information by using the divided visual field (DVF) method, with words and pictures. Two main theoretical models have been considered, (a) the HAROLD model which posits that aging is associated with supplementary recruitment of the right hemisphere (RH) and decreased hemispheric specialization, and (b) the RH decline theory, which assumes that the RH becomes less efficient with aging, associated with increased LH specialization. Two groups of subjects were examined, a Young Group (YG) and an Old Group (OG), while participants performed a semantic categorization task (living vs. non-living) in words and pictures. The DVF was realized in two steps: (a) unilateral DVF presentation with stimuli presented separately in each visual field, left or right, allowing for their initial processing by only one hemisphere, right or left, respectively; (b) bilateral DVF presentation (BVF) with stimuli presented simultaneously in both visual fields, followed by their processing by both hemispheres. These two types of presentation permitted the evaluation of two main characteristics of the inter-hemispheric processing of information, the hemispheric specialization (HS) and the inter-hemispheric cooperation (IHC). Moreover, the BVF allowed determining the driver-hemisphere for processing information presented in BVF. Results obtained in OG indicated that: (a) semantic categorization was performed as accurately as YG, even if more slowly, (b) a non-semantic RH decline was observed, and (c) the LH controls the semantic processing during the BVF, suggesting an increased role of the LH in aging. However, despite the stronger involvement of the LH in OG, the RH is not completely devoid of semantic abilities. As discussed in the paper, neither the HAROLD nor the RH decline does fully explain this pattern of results. We rather suggest that the effect of aging on the hemispheric specialization and inter-hemispheric cooperation during semantic processing is explained not by only one model, but by an interaction between several complementary mechanisms and models.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Hoyau E
University Grenoble Alpes, LPNC, F-38040 Grenoble, France; CNRS, LPNC UMR 5105, F-38040 Grenoble, France.
Cousin E
University Grenoble Alpes, LPNC, F-38040 Grenoble, France; CNRS, LPNC UMR 5105, F-38040 Grenoble, France; UMS IRMaGe, IRM 3T, CHU Grenoble, University Grenoble Alpes, F-38043 Grenoble, France.
Jaillard A
UMS IRMaGe, IRM 3T, CHU Grenoble, University Grenoble Alpes, F-38043 Grenoble, France.
Baciu M
University Grenoble Alpes, LPNC, F-38040 Grenoble, France; CNRS, LPNC UMR 5105, F-38040 Grenoble, France. Electronic address: mbaciu@upmf-grenoble.fr.

MeSH

AdultAgedAged, 80 and overAgingAnalysis of VarianceFemaleFunctional LateralityHumansMaleMental Status ScheduleMiddle AgedNeuropsychological TestsPattern Recognition, VisualPhotic StimulationReaction TimeSemantics

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26724229

Citation

Hoyau, E, et al. "Modulation of the Inter-hemispheric Processing of Semantic Information During Normal Aging. a Divided Visual Field Experiment." Neuropsychologia, vol. 93, no. Pt B, 2016, pp. 425-436.
Hoyau E, Cousin E, Jaillard A, et al. Modulation of the inter-hemispheric processing of semantic information during normal aging. A divided visual field experiment. Neuropsychologia. 2016;93(Pt B):425-436.
Hoyau, E., Cousin, E., Jaillard, A., & Baciu, M. (2016). Modulation of the inter-hemispheric processing of semantic information during normal aging. A divided visual field experiment. Neuropsychologia, 93(Pt B), 425-436. https://doi.org/10.1016/j.neuropsychologia.2015.12.027
Hoyau E, et al. Modulation of the Inter-hemispheric Processing of Semantic Information During Normal Aging. a Divided Visual Field Experiment. Neuropsychologia. 2016;93(Pt B):425-436. PubMed PMID: 26724229.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Modulation of the inter-hemispheric processing of semantic information during normal aging. A divided visual field experiment. AU - Hoyau,E, AU - Cousin,E, AU - Jaillard,A, AU - Baciu,M, Y1 - 2015/12/23/ PY - 2015/07/18/received PY - 2015/11/12/revised PY - 2015/12/22/accepted PY - 2016/1/3/pubmed PY - 2017/5/10/medline PY - 2016/1/3/entrez KW - Aging KW - DVF KW - Hemispheric Specialization KW - Language KW - Semantics SP - 425 EP - 436 JF - Neuropsychologia JO - Neuropsychologia VL - 93 IS - Pt B N2 - We evaluated the effect of normal aging on the inter-hemispheric processing of semantic information by using the divided visual field (DVF) method, with words and pictures. Two main theoretical models have been considered, (a) the HAROLD model which posits that aging is associated with supplementary recruitment of the right hemisphere (RH) and decreased hemispheric specialization, and (b) the RH decline theory, which assumes that the RH becomes less efficient with aging, associated with increased LH specialization. Two groups of subjects were examined, a Young Group (YG) and an Old Group (OG), while participants performed a semantic categorization task (living vs. non-living) in words and pictures. The DVF was realized in two steps: (a) unilateral DVF presentation with stimuli presented separately in each visual field, left or right, allowing for their initial processing by only one hemisphere, right or left, respectively; (b) bilateral DVF presentation (BVF) with stimuli presented simultaneously in both visual fields, followed by their processing by both hemispheres. These two types of presentation permitted the evaluation of two main characteristics of the inter-hemispheric processing of information, the hemispheric specialization (HS) and the inter-hemispheric cooperation (IHC). Moreover, the BVF allowed determining the driver-hemisphere for processing information presented in BVF. Results obtained in OG indicated that: (a) semantic categorization was performed as accurately as YG, even if more slowly, (b) a non-semantic RH decline was observed, and (c) the LH controls the semantic processing during the BVF, suggesting an increased role of the LH in aging. However, despite the stronger involvement of the LH in OG, the RH is not completely devoid of semantic abilities. As discussed in the paper, neither the HAROLD nor the RH decline does fully explain this pattern of results. We rather suggest that the effect of aging on the hemispheric specialization and inter-hemispheric cooperation during semantic processing is explained not by only one model, but by an interaction between several complementary mechanisms and models. SN - 1873-3514 UR - https://www.unboundmedicine.com/medline/citation/26724229/Modulation_of_the_inter_hemispheric_processing_of_semantic_information_during_normal_aging__A_divided_visual_field_experiment_ DB - PRIME DP - Unbound Medicine ER -