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Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
Ayu. 2015 Jan-Mar; 36(1):63-8.AYU

Abstract

INTRODUCTION

Ashwagandha (Withania somnifera [L.] Dunal) has been traditionally used for various actions ranging from vitalizer, improve endurance and stamina, promote longevity, improve immunity, and male and female fertility. However, clinical studies are needed to prove the clinical efficacy of this herb, especially in cardiovascular endurance and physical performance.

AIMS

This prospective, double-blind, randomized, and placebo-controlled study evaluated the efficacy of Ashwagandha roots extract in enhancing cardiorespiratory endurance and improving the quality of life (QOL) in 50 healthy male/female athletic adults.

MATERIALS AND METHODS

Cardiorespiratory endurance was assessed by measuring the oxygen consumption at peak physical exertion (VO2 max) levels during a 20 m shuttle run test. The World Health Organization self-reported QOL questionnaire (physical health, psychological health, social relationships, and environmental factors) was used to assess the QOL. Student's t-test was used to compare the differences in a mean and change from baseline VO2 max levels, whereas Wilcoxon signed-rank test was used to assess changes in QOL scores from baseline in the two groups.

RESULTS

There was a greater increase from baseline (P < 0.0001) in the mean VO2 max with KSM-66 Ashwagandha (n = 24) compared to placebo (n = 25) at 8 weeks (4.91 and 1.42, respectively) and at 12 weeks (5.67 and 1.86 respectively). The QOL scores for all subdomains significantly improved to a greater extent in the Ashwagandha group at 12 weeks compared to placebo (P < 0.05).

CONCLUSION

The findings suggest that Ashwagandha root extract enhances the cardiorespiratory endurance and improves QOL in healthy athletic adults.

Authors+Show Affiliations

Hyderabad Spine Clinic, Hyderabad, Andhra Pradesh, India.Zela Life Health Center, Bengaluru, Karnataka, India.Department of Pharmacology, BVDU Dental College and Hospital, Navi Mumbai, Maharashtra, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26730141

Citation

Choudhary, Bakhtiar, et al. "Efficacy of Ashwagandha (Withania Somnifera [L.] Dunal) in Improving Cardiorespiratory Endurance in Healthy Athletic Adults." Ayu, vol. 36, no. 1, 2015, pp. 63-8.
Choudhary B, Shetty A, Langade DG. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu. 2015;36(1):63-8.
Choudhary, B., Shetty, A., & Langade, D. G. (2015). Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu, 36(1), 63-8. https://doi.org/10.4103/0974-8520.169002
Choudhary B, Shetty A, Langade DG. Efficacy of Ashwagandha (Withania Somnifera [L.] Dunal) in Improving Cardiorespiratory Endurance in Healthy Athletic Adults. Ayu. 2015 Jan-Mar;36(1):63-8. PubMed PMID: 26730141.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. AU - Choudhary,Bakhtiar, AU - Shetty,A, AU - Langade,Deepak G, PY - 2016/1/6/entrez PY - 2016/1/6/pubmed PY - 2016/1/6/medline KW - Ashwagandha KW - VO2 max KW - cardiorespiratory endurance KW - healthy athletics adults KW - quality of life SP - 63 EP - 8 JF - Ayu JO - Ayu VL - 36 IS - 1 N2 - INTRODUCTION: Ashwagandha (Withania somnifera [L.] Dunal) has been traditionally used for various actions ranging from vitalizer, improve endurance and stamina, promote longevity, improve immunity, and male and female fertility. However, clinical studies are needed to prove the clinical efficacy of this herb, especially in cardiovascular endurance and physical performance. AIMS: This prospective, double-blind, randomized, and placebo-controlled study evaluated the efficacy of Ashwagandha roots extract in enhancing cardiorespiratory endurance and improving the quality of life (QOL) in 50 healthy male/female athletic adults. MATERIALS AND METHODS: Cardiorespiratory endurance was assessed by measuring the oxygen consumption at peak physical exertion (VO2 max) levels during a 20 m shuttle run test. The World Health Organization self-reported QOL questionnaire (physical health, psychological health, social relationships, and environmental factors) was used to assess the QOL. Student's t-test was used to compare the differences in a mean and change from baseline VO2 max levels, whereas Wilcoxon signed-rank test was used to assess changes in QOL scores from baseline in the two groups. RESULTS: There was a greater increase from baseline (P < 0.0001) in the mean VO2 max with KSM-66 Ashwagandha (n = 24) compared to placebo (n = 25) at 8 weeks (4.91 and 1.42, respectively) and at 12 weeks (5.67 and 1.86 respectively). The QOL scores for all subdomains significantly improved to a greater extent in the Ashwagandha group at 12 weeks compared to placebo (P < 0.05). CONCLUSION: The findings suggest that Ashwagandha root extract enhances the cardiorespiratory endurance and improves QOL in healthy athletic adults. SN - 0974-8520 UR - https://www.unboundmedicine.com/medline/citation/26730141/Efficacy_of_Ashwagandha__Withania_somnifera_[L_]_Dunal__in_improving_cardiorespiratory_endurance_in_healthy_athletic_adults_ L2 - http://www.ayujournal.org/article.asp?issn=0974-8520;year=2015;volume=36;issue=1;spage=63;epage=68;aulast=Choudhary DB - PRIME DP - Unbound Medicine ER -
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