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Study of multidrug therapy in paucibacillary leprosy.
J Indian Med Assoc. 1989 Feb; 87(2):34-6.JI

Abstract

A study was undertaken to evaluate the efficacy of multidrug therapy (MDT) in paucibacillary leprosy. Out of 155 fresh cases studied 48 had indeterminate, 38 tuberculoid and 69 had borderline tuberculoid leprosy. Out of 155 cases, 64 patients in the first group were treated with dapsone 100 mg daily for 12 months. In the second group, 91 patients were given MDT, consisting of rifampicin 600 mg once a month and dapsone 100 mg daily for consecutive 12 months. The cases receiving dapsone and the cases having MDT remained clinically active at the end of 6 months in 56.1% and 37.2% respectively; 13.1% of cases having single lesion and 66.3% of patients with multiple lesions were found to be active after 6 months of MDT. At the end of one year 79.6% cases receiving dapsone and 91.2% cases having MDT became inactive.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2674283

Citation

Kar, P K., and A S. Sohi. "Study of Multidrug Therapy in Paucibacillary Leprosy." Journal of the Indian Medical Association, vol. 87, no. 2, 1989, pp. 34-6.
Kar PK, Sohi AS. Study of multidrug therapy in paucibacillary leprosy. J Indian Med Assoc. 1989;87(2):34-6.
Kar, P. K., & Sohi, A. S. (1989). Study of multidrug therapy in paucibacillary leprosy. Journal of the Indian Medical Association, 87(2), 34-6.
Kar PK, Sohi AS. Study of Multidrug Therapy in Paucibacillary Leprosy. J Indian Med Assoc. 1989;87(2):34-6. PubMed PMID: 2674283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study of multidrug therapy in paucibacillary leprosy. AU - Kar,P K, AU - Sohi,A S, PY - 1989/2/1/pubmed PY - 1989/2/1/medline PY - 1989/2/1/entrez SP - 34 EP - 6 JF - Journal of the Indian Medical Association JO - J Indian Med Assoc VL - 87 IS - 2 N2 - A study was undertaken to evaluate the efficacy of multidrug therapy (MDT) in paucibacillary leprosy. Out of 155 fresh cases studied 48 had indeterminate, 38 tuberculoid and 69 had borderline tuberculoid leprosy. Out of 155 cases, 64 patients in the first group were treated with dapsone 100 mg daily for 12 months. In the second group, 91 patients were given MDT, consisting of rifampicin 600 mg once a month and dapsone 100 mg daily for consecutive 12 months. The cases receiving dapsone and the cases having MDT remained clinically active at the end of 6 months in 56.1% and 37.2% respectively; 13.1% of cases having single lesion and 66.3% of patients with multiple lesions were found to be active after 6 months of MDT. At the end of one year 79.6% cases receiving dapsone and 91.2% cases having MDT became inactive. SN - 0019-5847 UR - https://www.unboundmedicine.com/medline/citation/2674283/Study_of_multidrug_therapy_in_paucibacillary_leprosy_ L2 - https://medlineplus.gov/mycobacterialinfections.html DB - PRIME DP - Unbound Medicine ER -