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(68)Ga-DOTATOC-PET/CT for effective diagnosis and treatment of pancreatic tail gastrinoma with multiple liver metastases: a case report.
Nihon Shokakibyo Gakkai Zasshi. 2016; 113(1):86-93.NS

Abstract

A 40-year-old man admitted to our hospital with diarrhea underwent abdominal computed tomography (CT) which showed multiple masses in the liver and pancreatic tail. Although there were no abnormal accumulations with fluorodeoxyglucose ((18)F) positron emission tomography (FDG-PET), (68)Ga-DOTATOC-PET/CT detected obvious abnormal accumulations for the both lobes of liver and pancreatic tail tumors. The serum gastrin was markedly high, and liver tumor biopsy demonstrated the presence of malignant cells with round nuclei that were positive for gastrin and somatostatin receptor. The patient was diagnosed with pancreatic tail gastrinoma with multiple liver metastases and treated with octreotide, everolimus, and a proton pump inhibitor which functionally controlled tumor growth. This case demonstrates (68)Ga-DOTATOC-PET/CT as a useful modality for the localization, qualitative diagnosis, and treatment of gastrinoma.

Authors+Show Affiliations

Department of Gastroenterology, Japanese Red Cross Kyoto Daiichi Hospital.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

jpn

PubMed ID

26743558

Citation

Matsumura, Shinya, et al. "(68)Ga-DOTATOC-PET/CT for Effective Diagnosis and Treatment of Pancreatic Tail Gastrinoma With Multiple Liver Metastases: a Case Report." Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-enterology, vol. 113, no. 1, 2016, pp. 86-93.
Matsumura S, Okuyama Y, Doi R, et al. (68)Ga-DOTATOC-PET/CT for effective diagnosis and treatment of pancreatic tail gastrinoma with multiple liver metastases: a case report. Nihon Shokakibyo Gakkai Zasshi. 2016;113(1):86-93.
Matsumura, S., Okuyama, Y., Doi, R., Nakao, R., Urata, Y., & Yoshida, N. (2016). (68)Ga-DOTATOC-PET/CT for effective diagnosis and treatment of pancreatic tail gastrinoma with multiple liver metastases: a case report. Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-enterology, 113(1), 86-93. https://doi.org/10.11405/nisshoshi.113.86
Matsumura S, et al. (68)Ga-DOTATOC-PET/CT for Effective Diagnosis and Treatment of Pancreatic Tail Gastrinoma With Multiple Liver Metastases: a Case Report. Nihon Shokakibyo Gakkai Zasshi. 2016;113(1):86-93. PubMed PMID: 26743558.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - (68)Ga-DOTATOC-PET/CT for effective diagnosis and treatment of pancreatic tail gastrinoma with multiple liver metastases: a case report. AU - Matsumura,Shinya, AU - Okuyama,Yusuke, AU - Doi,Ryuichiro, AU - Nakao,Ryuta, AU - Urata,Yoji, AU - Yoshida,Norimasa, PY - 2016/1/9/entrez PY - 2016/1/9/pubmed PY - 2017/2/23/medline SP - 86 EP - 93 JF - Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology JO - Nihon Shokakibyo Gakkai Zasshi VL - 113 IS - 1 N2 - A 40-year-old man admitted to our hospital with diarrhea underwent abdominal computed tomography (CT) which showed multiple masses in the liver and pancreatic tail. Although there were no abnormal accumulations with fluorodeoxyglucose ((18)F) positron emission tomography (FDG-PET), (68)Ga-DOTATOC-PET/CT detected obvious abnormal accumulations for the both lobes of liver and pancreatic tail tumors. The serum gastrin was markedly high, and liver tumor biopsy demonstrated the presence of malignant cells with round nuclei that were positive for gastrin and somatostatin receptor. The patient was diagnosed with pancreatic tail gastrinoma with multiple liver metastases and treated with octreotide, everolimus, and a proton pump inhibitor which functionally controlled tumor growth. This case demonstrates (68)Ga-DOTATOC-PET/CT as a useful modality for the localization, qualitative diagnosis, and treatment of gastrinoma. SN - 0446-6586 UR - https://www.unboundmedicine.com/medline/citation/26743558/_68_Ga_DOTATOC_PET/CT_for_effective_diagnosis_and_treatment_of_pancreatic_tail_gastrinoma_with_multiple_liver_metastases:_a_case_report_ L2 - https://dx.doi.org/10.11405/nisshoshi.113.86 DB - PRIME DP - Unbound Medicine ER -