Tags

Type your tag names separated by a space and hit enter

Alkaloids with antioxidant activities from Aconitum handelianum.
J Asian Nat Prod Res. 2016 Jun; 18(6):603-10.JA

Abstract

A new C20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C20-diterpenoid alkaloids with vicinal-triol system and benzyltetrahydroisoquinoline alkaloids exhibited significant antioxidant activities measured by three antioxidant test systems. The aconitine-type C19-diterpenoid alkaloids could serve as potential secondary antioxidants for their strong binding effects to metal ions.

Authors+Show Affiliations

a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology , Yunnan University , Kunming 650091 , China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26744060

Citation

Yin, Tian-Peng, et al. "Alkaloids With Antioxidant Activities From Aconitum Handelianum." Journal of Asian Natural Products Research, vol. 18, no. 6, 2016, pp. 603-10.
Yin TP, Cai L, Xing Y, et al. Alkaloids with antioxidant activities from Aconitum handelianum. J Asian Nat Prod Res. 2016;18(6):603-10.
Yin, T. P., Cai, L., Xing, Y., Yu, J., Li, X. J., Mei, R. F., & Ding, Z. T. (2016). Alkaloids with antioxidant activities from Aconitum handelianum. Journal of Asian Natural Products Research, 18(6), 603-10. https://doi.org/10.1080/10286020.2015.1114473
Yin TP, et al. Alkaloids With Antioxidant Activities From Aconitum Handelianum. J Asian Nat Prod Res. 2016;18(6):603-10. PubMed PMID: 26744060.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alkaloids with antioxidant activities from Aconitum handelianum. AU - Yin,Tian-Peng, AU - Cai,Le, AU - Xing,Yun, AU - Yu,Jing, AU - Li,Xue-Jiao, AU - Mei,Rui-Feng, AU - Ding,Zhong-Tao, Y1 - 2016/01/08/ PY - 2016/1/9/entrez PY - 2016/1/9/pubmed PY - 2017/1/21/medline KW - Aconitum handelianum KW - Ranunculaceae KW - antioxidant KW - diterpenoid alkaloid KW - handelidine SP - 603 EP - 10 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 18 IS - 6 N2 - A new C20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C20-diterpenoid alkaloids with vicinal-triol system and benzyltetrahydroisoquinoline alkaloids exhibited significant antioxidant activities measured by three antioxidant test systems. The aconitine-type C19-diterpenoid alkaloids could serve as potential secondary antioxidants for their strong binding effects to metal ions. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/26744060/Alkaloids_with_antioxidant_activities_from_Aconitum_handelianum_ L2 - https://www.tandfonline.com/doi/full/10.1080/10286020.2015.1114473 DB - PRIME DP - Unbound Medicine ER -