Synthesis of 3-alkyl spiro[4,5]trienones by copper-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes.Chem Commun (Camb). 2016 Feb 11; 52(12):2573-6.CC
Abstract
A Cu-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes for the synthesis of 3-alkyl spiro[4,5]trienones is described. This method allows the formation of two carbon-carbon bonds and one carbon-oxygen bond in a single reaction through a sequence of C-H oxidative coupling, ipso-carbocyclization and dearomatization.
Links
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
26744747
Citation
Ouyang, Xuan-Hui, et al. "Synthesis of 3-alkyl Spiro[4,5]trienones By Copper-catalyzed Oxidative Ipso-annulation of Activated Alkynes With Unactivated Alkanes." Chemical Communications (Cambridge, England), vol. 52, no. 12, 2016, pp. 2573-6.
Ouyang XH, Song RJ, Liu B, et al. Synthesis of 3-alkyl spiro[4,5]trienones by copper-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes. Chem Commun (Camb). 2016;52(12):2573-6.
Ouyang, X. H., Song, R. J., Liu, B., & Li, J. H. (2016). Synthesis of 3-alkyl spiro[4,5]trienones by copper-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes. Chemical Communications (Cambridge, England), 52(12), 2573-6. https://doi.org/10.1039/c5cc08952b
Ouyang XH, et al. Synthesis of 3-alkyl Spiro[4,5]trienones By Copper-catalyzed Oxidative Ipso-annulation of Activated Alkynes With Unactivated Alkanes. Chem Commun (Camb). 2016 Feb 11;52(12):2573-6. PubMed PMID: 26744747.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Synthesis of 3-alkyl spiro[4,5]trienones by copper-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes.
AU - Ouyang,Xuan-Hui,
AU - Song,Ren-Jie,
AU - Liu,Bang,
AU - Li,Jin-Heng,
Y1 - 2016/01/08/
PY - 2016/1/9/entrez
PY - 2016/1/9/pubmed
PY - 2016/1/9/medline
SP - 2573
EP - 6
JF - Chemical communications (Cambridge, England)
JO - Chem Commun (Camb)
VL - 52
IS - 12
N2 - A Cu-catalyzed oxidative ipso-annulation of activated alkynes with unactivated alkanes for the synthesis of 3-alkyl spiro[4,5]trienones is described. This method allows the formation of two carbon-carbon bonds and one carbon-oxygen bond in a single reaction through a sequence of C-H oxidative coupling, ipso-carbocyclization and dearomatization.
SN - 1364-548X
UR - https://www.unboundmedicine.com/medline/citation/26744747/Synthesis_of_3_alkyl_spiro[45]trienones_by_copper_catalyzed_oxidative_ipso_annulation_of_activated_alkynes_with_unactivated_alkanes_
DB - PRIME
DP - Unbound Medicine
ER -
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