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AISF position paper on liver disease and pregnancy.
Dig Liver Dis. 2016 Feb; 48(2):120-37.DL

Abstract

The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.

Pub Type(s)

Journal Article
Practice Guideline
Review

Language

eng

PubMed ID

26747754

Citation

Italian Association for the Study of the Liver (AISF), and Italian Association for the Study of the Liver AISF. "AISF Position Paper On Liver Disease and Pregnancy." Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 48, no. 2, 2016, pp. 120-37.
Italian Association for the Study of the Liver (AISF), Italian Association for the Study of the Liver AISF. AISF position paper on liver disease and pregnancy. Dig Liver Dis. 2016;48(2):120-37.
Italian Association for the Study of the Liver (AISF). (2016). AISF position paper on liver disease and pregnancy. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 48(2), 120-37. https://doi.org/10.1016/j.dld.2015.11.004
Italian Association for the Study of the Liver (AISF), Italian Association for the Study of the Liver AISF. AISF Position Paper On Liver Disease and Pregnancy. Dig Liver Dis. 2016;48(2):120-37. PubMed PMID: 26747754.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - AISF position paper on liver disease and pregnancy. AU - ,, AU - ,, Y1 - 2015/11/14/ PY - 2015/06/15/received PY - 2015/10/29/revised PY - 2015/11/06/accepted PY - 2016/1/10/entrez PY - 2016/1/10/pubmed PY - 2016/12/15/medline KW - Liver diseases KW - Pregnancy SP - 120 EP - 37 JF - Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver JO - Dig Liver Dis VL - 48 IS - 2 N2 - The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported. SN - 1878-3562 UR - https://www.unboundmedicine.com/medline/citation/26747754/AISF_position_paper_on_liver_disease_and_pregnancy_ DB - PRIME DP - Unbound Medicine ER -