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Composition, in vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus thunbergii from Taiwan.
Nat Prod Commun. 2015 Nov; 10(11):2013-6.NP

Abstract

This study investigated the chemical composition, in-vitro cytotoxicity, and anti-mildew fungal activities of the essential oil isolated from the leaf of Machilus thunbergii from Taiwan. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Eighty-three compounds were identified, representing 99.8% of the oil. The main components identified were n-decanal (26.6%), β-caryophyllene (15.8%), α-humulene (10.8%), and β-eudesmol (10.5%). The oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells. The active source compounds were β-caryophyllene, a-humulene, and β-eudesmol. The anti-mildew activity of the leaf oil was also evaluated. Results showed that the leaf oil had excellent anti-mildew activity. For the anti-mildew activity of the leaf oil, the active source compound was determined to be β-eudesmol.

Authors

Su YC
No affiliation info available
Hsu KP
No affiliation info available
Li SC
No affiliation info available
Ho CL
No affiliation info available

MeSH

Antifungal AgentsAntineoplastic Agents, PhytogenicCell Line, TumorFungiHumansLauraceaeMicrobial Sensitivity TestsOils, VolatilePlant ExtractsPlant LeavesTaiwan

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26749851

Citation

Su, Yu-Chang, et al. "Composition, in Vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus Thunbergii From Taiwan." Natural Product Communications, vol. 10, no. 11, 2015, pp. 2013-6.
Su YC, Hsu KP, Li SC, et al. Composition, in vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus thunbergii from Taiwan. Nat Prod Commun. 2015;10(11):2013-6.
Su, Y. C., Hsu, K. P., Li, S. C., & Ho, C. L. (2015). Composition, in vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus thunbergii from Taiwan. Natural Product Communications, 10(11), 2013-6.
Su YC, et al. Composition, in Vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus Thunbergii From Taiwan. Nat Prod Commun. 2015;10(11):2013-6. PubMed PMID: 26749851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition, in vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus thunbergii from Taiwan. AU - Su,Yu-Chang, AU - Hsu,Kuan-Ping, AU - Li,Shu-Ching, AU - Ho,Chen-Lung, PY - 2016/1/12/entrez PY - 2016/1/12/pubmed PY - 2016/2/19/medline SP - 2013 EP - 6 JF - Natural product communications JO - Nat Prod Commun VL - 10 IS - 11 N2 - This study investigated the chemical composition, in-vitro cytotoxicity, and anti-mildew fungal activities of the essential oil isolated from the leaf of Machilus thunbergii from Taiwan. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Eighty-three compounds were identified, representing 99.8% of the oil. The main components identified were n-decanal (26.6%), β-caryophyllene (15.8%), α-humulene (10.8%), and β-eudesmol (10.5%). The oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells. The active source compounds were β-caryophyllene, a-humulene, and β-eudesmol. The anti-mildew activity of the leaf oil was also evaluated. Results showed that the leaf oil had excellent anti-mildew activity. For the anti-mildew activity of the leaf oil, the active source compound was determined to be β-eudesmol. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/26749851/Composition_in_vitro_Cytotoxicity_and_Anti_mildew_Activities_of_the_Leaf_Essential_Oil_of_Machilus_thunbergii_from_Taiwan_ DB - PRIME DP - Unbound Medicine ER -