Tags

Type your tag names separated by a space and hit enter

Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men.
Eur J Heart Fail 2016; 18(3):253-9EJ

Abstract

AIMS

We examined the hypothesis that high adherence to a Mediterranean diet reduces the risk of developing heart failure (HF) as well as the risk of death from HF.

METHODS AND RESULTS

The study population comprised 37 308 men from the Cohort of Swedish Men who were free from cardiovascular disease at baseline. The modified Mediterranean diet (mMED) score was created from a self-administered food frequency questionnaire, based on consumption of presumed beneficial/detrimental foods, on a 0-8 scale. Incident HF events were ascertained by linkage to the Swedish National Patient and the Cause of Death Registers. Relative risks (RR) with 95% confidence intervals (CI), adjusted for potential confounders, were estimated by Cox proportional hazards regression models. We identified 146 deaths from HF and 1269 incident HF events over a median follow-up of 10.9 years (1998-2008). The mMED score was inversely associated with risk of HF (multivariable RR for the highest vs. lowest quartile 0.69, 95% CI 0.57, 0.83); the corresponding RR of HF mortality was 0.55 (95% CI 0.31, 0.98). The multivariable RR for every two-point increment in the mMED score was 0.85 (95% CI 0.78, 0.91) for incidence of HF and 0.78 (95% CI 0.62, 0.98) for mortality from HF, respectively.

CONCLUSIONS

High adherence to a Mediterranean diet was associated with a lower risk of HF and mortality from HF in men. Further studies are needed to replicate these findings in other populations.

Authors+Show Affiliations

Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden.Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden.Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden. Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd University Hospital, Stockholm, Sweden.Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden.Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26781788

Citation

Tektonidis, Thanasis G., et al. "Adherence to a Mediterranean Diet Is Associated With Reduced Risk of Heart Failure in Men." European Journal of Heart Failure, vol. 18, no. 3, 2016, pp. 253-9.
Tektonidis TG, Åkesson A, Gigante B, et al. Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men. Eur J Heart Fail. 2016;18(3):253-9.
Tektonidis, T. G., Åkesson, A., Gigante, B., Wolk, A., & Larsson, S. C. (2016). Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men. European Journal of Heart Failure, 18(3), pp. 253-9. doi:10.1002/ejhf.481.
Tektonidis TG, et al. Adherence to a Mediterranean Diet Is Associated With Reduced Risk of Heart Failure in Men. Eur J Heart Fail. 2016;18(3):253-9. PubMed PMID: 26781788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men. AU - Tektonidis,Thanasis G, AU - Åkesson,Agneta, AU - Gigante,Bruna, AU - Wolk,Alicja, AU - Larsson,Susanna C, Y1 - 2016/01/18/ PY - 2015/09/04/received PY - 2015/11/10/revised PY - 2015/12/12/accepted PY - 2016/1/20/entrez PY - 2016/1/20/pubmed PY - 2016/12/15/medline KW - Heart failure KW - Mediterranean diet KW - Men KW - Primary prevention KW - Prospective studies SP - 253 EP - 9 JF - European journal of heart failure JO - Eur. J. Heart Fail. VL - 18 IS - 3 N2 - AIMS: We examined the hypothesis that high adherence to a Mediterranean diet reduces the risk of developing heart failure (HF) as well as the risk of death from HF. METHODS AND RESULTS: The study population comprised 37 308 men from the Cohort of Swedish Men who were free from cardiovascular disease at baseline. The modified Mediterranean diet (mMED) score was created from a self-administered food frequency questionnaire, based on consumption of presumed beneficial/detrimental foods, on a 0-8 scale. Incident HF events were ascertained by linkage to the Swedish National Patient and the Cause of Death Registers. Relative risks (RR) with 95% confidence intervals (CI), adjusted for potential confounders, were estimated by Cox proportional hazards regression models. We identified 146 deaths from HF and 1269 incident HF events over a median follow-up of 10.9 years (1998-2008). The mMED score was inversely associated with risk of HF (multivariable RR for the highest vs. lowest quartile 0.69, 95% CI 0.57, 0.83); the corresponding RR of HF mortality was 0.55 (95% CI 0.31, 0.98). The multivariable RR for every two-point increment in the mMED score was 0.85 (95% CI 0.78, 0.91) for incidence of HF and 0.78 (95% CI 0.62, 0.98) for mortality from HF, respectively. CONCLUSIONS: High adherence to a Mediterranean diet was associated with a lower risk of HF and mortality from HF in men. Further studies are needed to replicate these findings in other populations. SN - 1879-0844 UR - https://www.unboundmedicine.com/medline/citation/26781788/full_citation L2 - https://doi.org/10.1002/ejhf.481 DB - PRIME DP - Unbound Medicine ER -