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Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis.
Sci Rep 2016; 6:19783SR

Abstract

Association between dietary intake of vegetables and fruits and risk of hip fracture has been reported for many years. However, the findings remain inconclusive. We conducted a meta-analysis to evaluate the relationship between intake of vegetables and fruits, and risk of hip fracture. Literature search for relevant studies was performed on PubMed and Embase databases. Five observational studies were included in the meta-analysis. Summary hazard ratio (HR) with corresponding 95% confidence interval (CI) was calculated from pooled data using the random-effects model irrespective of heterogeneity. Sensitivity and subgroup analysis were performed to explore possible reasons for heterogeneity. The summary HR for hip fracture in relation to high intake vs. low intake of only vegetables, only fruits, and combined intake of fruits and vegetables, was 0.75 (95% CI, 0.61-0.92), 0.87 (95% CI, 0.74-1.04), and 0.79 (95% CI, 0.61-1.03), respectively. Subgroup analyses based on study design, geographical location, number of cases, and gender showed similar results. Increased intake of vegetables, but not fruits, was found to be associated with a lower risk of hip fracture. Large prospective clinical trials with robust methodology are required to confirm our findings.

Authors+Show Affiliations

Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.Department of Oral and Maxillary Surgery, Gui Zhou provincial people's hospital, Guiyang, China.

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

26806285

Citation

Luo, Si yang, et al. "Increased Intake of Vegetables, but Not Fruits, May Be Associated With Reduced Risk of Hip Fracture: a Meta-analysis." Scientific Reports, vol. 6, 2016, p. 19783.
Luo Sy, Li Y, Luo H, et al. Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis. Sci Rep. 2016;6:19783.
Luo, S. y., Li, Y., Luo, H., Yin, X. h., Lin, d. u. . R., Zhao, K., ... Song, J. k. (2016). Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis. Scientific Reports, 6, p. 19783. doi:10.1038/srep19783.
Luo Sy, et al. Increased Intake of Vegetables, but Not Fruits, May Be Associated With Reduced Risk of Hip Fracture: a Meta-analysis. Sci Rep. 2016 Jan 25;6:19783. PubMed PMID: 26806285.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis. AU - Luo,Si yang, AU - Li,Yan, AU - Luo,Hong, AU - Yin,Xin hai, AU - Lin,Du ren, AU - Zhao,Ke, AU - Huang,Guang lei, AU - Song,Ju kun, Y1 - 2016/01/25/ PY - 2015/09/07/received PY - 2015/12/17/accepted PY - 2016/1/26/entrez PY - 2016/1/26/pubmed PY - 2016/12/15/medline SP - 19783 EP - 19783 JF - Scientific reports JO - Sci Rep VL - 6 N2 - Association between dietary intake of vegetables and fruits and risk of hip fracture has been reported for many years. However, the findings remain inconclusive. We conducted a meta-analysis to evaluate the relationship between intake of vegetables and fruits, and risk of hip fracture. Literature search for relevant studies was performed on PubMed and Embase databases. Five observational studies were included in the meta-analysis. Summary hazard ratio (HR) with corresponding 95% confidence interval (CI) was calculated from pooled data using the random-effects model irrespective of heterogeneity. Sensitivity and subgroup analysis were performed to explore possible reasons for heterogeneity. The summary HR for hip fracture in relation to high intake vs. low intake of only vegetables, only fruits, and combined intake of fruits and vegetables, was 0.75 (95% CI, 0.61-0.92), 0.87 (95% CI, 0.74-1.04), and 0.79 (95% CI, 0.61-1.03), respectively. Subgroup analyses based on study design, geographical location, number of cases, and gender showed similar results. Increased intake of vegetables, but not fruits, was found to be associated with a lower risk of hip fracture. Large prospective clinical trials with robust methodology are required to confirm our findings. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/26806285/full_citation L2 - http://dx.doi.org/10.1038/srep19783 DB - PRIME DP - Unbound Medicine ER -