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Ejaculatory physiology and pathophysiology: assessment and treatment in male infertility.
Transl Androl Urol. 2014 Mar; 3(1):41-9.TA

Abstract

Azoospermia is a heterogeneous condition with multiple etiologies and a variety of treatments. In this chapter we present a summary of retrograde ejaculation and anejaculation, both of which are characterized by an absence of antegrade semen propulsion through the male reproductive tract. Each of these affects fertility, but is pathophysiologically distinct disorders with differing evaluation and treatment. Retrograde ejaculation has a myriad of well-characterized causes, from pharmacologic disruption to interference of neural mechanisms by surgical intervention for a variety of diseases. Medication is the mainstay of treatment, although only a minority responds and develops antegrade ejaculation. For the men who are not responders to medical therapy, but still have fertility goals, there are a variety of sperm retrieval techniques to assist their reproductive abilities. Failure of emission is characterized by an absence of the emission phase and no antegrade or retrograde expulsion of ejaculatory products. If fertility is desired, these men must rely on assisted ejaculatory procedures, and treatment choice is guided by etiology and response. Ultimately, retrograde ejaculation and failure of emission are in a spectrum of ejaculatory disorders which impair male fertility.

Authors+Show Affiliations

1 Emory University, Department of Urology, Atlanta, Georgia, USA ; 2 Kaiser Permanente, Oakland Medical Center, Oakland, California, USA.1 Emory University, Department of Urology, Atlanta, Georgia, USA ; 2 Kaiser Permanente, Oakland Medical Center, Oakland, California, USA.1 Emory University, Department of Urology, Atlanta, Georgia, USA ; 2 Kaiser Permanente, Oakland Medical Center, Oakland, California, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26816751

Citation

Revenig, Louis, et al. "Ejaculatory Physiology and Pathophysiology: Assessment and Treatment in Male Infertility." Translational Andrology and Urology, vol. 3, no. 1, 2014, pp. 41-9.
Revenig L, Leung A, Hsiao W. Ejaculatory physiology and pathophysiology: assessment and treatment in male infertility. Transl Androl Urol. 2014;3(1):41-9.
Revenig, L., Leung, A., & Hsiao, W. (2014). Ejaculatory physiology and pathophysiology: assessment and treatment in male infertility. Translational Andrology and Urology, 3(1), 41-9. https://doi.org/10.3978/j.issn.2223-4683.2014.02.02
Revenig L, Leung A, Hsiao W. Ejaculatory Physiology and Pathophysiology: Assessment and Treatment in Male Infertility. Transl Androl Urol. 2014;3(1):41-9. PubMed PMID: 26816751.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ejaculatory physiology and pathophysiology: assessment and treatment in male infertility. AU - Revenig,Louis, AU - Leung,Andrew, AU - Hsiao,Wayland, PY - 2016/1/28/entrez PY - 2014/3/1/pubmed PY - 2014/3/1/medline KW - Ejaculation KW - anejaculation KW - electroejaculation (EEJ) KW - penile vibratory stimulation (PVS) KW - retrograde ejaculation SP - 41 EP - 9 JF - Translational andrology and urology JO - Transl Androl Urol VL - 3 IS - 1 N2 - Azoospermia is a heterogeneous condition with multiple etiologies and a variety of treatments. In this chapter we present a summary of retrograde ejaculation and anejaculation, both of which are characterized by an absence of antegrade semen propulsion through the male reproductive tract. Each of these affects fertility, but is pathophysiologically distinct disorders with differing evaluation and treatment. Retrograde ejaculation has a myriad of well-characterized causes, from pharmacologic disruption to interference of neural mechanisms by surgical intervention for a variety of diseases. Medication is the mainstay of treatment, although only a minority responds and develops antegrade ejaculation. For the men who are not responders to medical therapy, but still have fertility goals, there are a variety of sperm retrieval techniques to assist their reproductive abilities. Failure of emission is characterized by an absence of the emission phase and no antegrade or retrograde expulsion of ejaculatory products. If fertility is desired, these men must rely on assisted ejaculatory procedures, and treatment choice is guided by etiology and response. Ultimately, retrograde ejaculation and failure of emission are in a spectrum of ejaculatory disorders which impair male fertility. SN - 2223-4691 UR - https://www.unboundmedicine.com/medline/citation/26816751/Ejaculatory_physiology_and_pathophysiology:_assessment_and_treatment_in_male_infertility_ L2 - https://doi.org/10.3978/j.issn.2223-4683.2014.02.02 DB - PRIME DP - Unbound Medicine ER -
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