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Prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia in men ≥75 years: a prospective single-center study.
World J Urol. 2016 Sep; 34(9):1275-83.WJ

Abstract

PURPOSE

To compare the safety and efficacy of PAE for the treatment of benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years.

METHODS

A total of 157 patients diagnosed with lower urinary tract symptoms (LUTS) due to BPH underwent PAE. Group A (n = 52) included patients ≥75 years, and group B (n = 105) included patients <75 years. Follow-up was performed using the International Prostate Symptoms Score (IPSS), quality of life (QoL), peak urinary flow rate (Q max), post-void residual volume (PVR), the International Index of Erectile Function short form (IIEF-5), prostatic-specific antigen (PSA), and prostate volume (PV), at 1, 3, 6, and every 6 months thereafter.

RESULTS

More coexistent systemic diseases were identified in group A than in group B (P < 0.05). Technical success rate of PAE was 90.4 % in group A and 95.2 % in group B (P = 0.06). A total of 147 patients had completed the follow-up with a mean of 20 months. Compared with the baseline, there were significant improvements in IPSS, QoL, Q max, PV, PVR, and PSA in both groups after PAE. There were no significant differences in the changes of IPSS, Q max, PVR, PSA, and IIEF-5 between groups after PAE. No major complications were noted.

CONCLUSION

PAE could be used as an effective, safe, and well tolerable method in the treatment of elderly symptomatic BPH patients, similarly to younger patients, and it may play an important role in patients in whom medical therapy has failed, who are at high surgical and anesthetic risk or who refuse the standard surgical therapy.

Authors+Show Affiliations

Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. wangmq@vip.sina.com.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.Department of Interventional Radiology, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26818021

Citation

Wang, Mao Qiang, et al. "Prostatic Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia in Men ≥75 Years: a Prospective Single-center Study." World Journal of Urology, vol. 34, no. 9, 2016, pp. 1275-83.
Wang MQ, Wang Y, Yan JY, et al. Prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia in men ≥75 years: a prospective single-center study. World J Urol. 2016;34(9):1275-83.
Wang, M. Q., Wang, Y., Yan, J. Y., Yuan, K., Zhang, G. D., Duan, F., & Li, K. (2016). Prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia in men ≥75 years: a prospective single-center study. World Journal of Urology, 34(9), 1275-83. https://doi.org/10.1007/s00345-016-1771-0
Wang MQ, et al. Prostatic Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia in Men ≥75 Years: a Prospective Single-center Study. World J Urol. 2016;34(9):1275-83. PubMed PMID: 26818021.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia in men ≥75 years: a prospective single-center study. AU - Wang,Mao Qiang, AU - Wang,Yan, AU - Yan,Jie Yu, AU - Yuan,Kai, AU - Zhang,Guo Dong, AU - Duan,Feng, AU - Li,Kai, Y1 - 2016/01/27/ PY - 2015/11/13/received PY - 2016/01/16/accepted PY - 2016/1/29/entrez PY - 2016/1/29/pubmed PY - 2017/4/19/medline KW - Aging disease KW - Angiography KW - Benign prostatic hyperplasia (BPH) KW - Lower urinary tract symptoms (LUTS) KW - Prostatic artery embolization (PAE) SP - 1275 EP - 83 JF - World journal of urology JO - World J Urol VL - 34 IS - 9 N2 - PURPOSE: To compare the safety and efficacy of PAE for the treatment of benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. METHODS: A total of 157 patients diagnosed with lower urinary tract symptoms (LUTS) due to BPH underwent PAE. Group A (n = 52) included patients ≥75 years, and group B (n = 105) included patients <75 years. Follow-up was performed using the International Prostate Symptoms Score (IPSS), quality of life (QoL), peak urinary flow rate (Q max), post-void residual volume (PVR), the International Index of Erectile Function short form (IIEF-5), prostatic-specific antigen (PSA), and prostate volume (PV), at 1, 3, 6, and every 6 months thereafter. RESULTS: More coexistent systemic diseases were identified in group A than in group B (P < 0.05). Technical success rate of PAE was 90.4 % in group A and 95.2 % in group B (P = 0.06). A total of 147 patients had completed the follow-up with a mean of 20 months. Compared with the baseline, there were significant improvements in IPSS, QoL, Q max, PV, PVR, and PSA in both groups after PAE. There were no significant differences in the changes of IPSS, Q max, PVR, PSA, and IIEF-5 between groups after PAE. No major complications were noted. CONCLUSION: PAE could be used as an effective, safe, and well tolerable method in the treatment of elderly symptomatic BPH patients, similarly to younger patients, and it may play an important role in patients in whom medical therapy has failed, who are at high surgical and anesthetic risk or who refuse the standard surgical therapy. SN - 1433-8726 UR - https://www.unboundmedicine.com/medline/citation/26818021/Prostatic_artery_embolization_for_the_treatment_of_symptomatic_benign_prostatic_hyperplasia_in_men_≥75_years:_a_prospective_single_center_study_ L2 - https://dx.doi.org/10.1007/s00345-016-1771-0 DB - PRIME DP - Unbound Medicine ER -