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Left ventricular volumes by echocardiography in chronic aortic and mitral regurgitations.
Scand Cardiovasc J. 2016 Jun; 50(3):154-61.SC

Abstract

Objectives Cut-off values for left ventricular (LV) dimensions indicating severe valve regurgitation have not been defined. The aim of this study was to establish echocardiographic cut-off values for LV dimensions indicating severe chronic aortic (AR) or mitral (MR) regurgitation. Design The hemodynamic significance was confirmed by documented reduction of end-diastolic volume (EDV) and symptom relief after surgery. Eighty-three patients with moderate or severe regurgitation (AR, n = 41; MR, n = 42) without other cardiac conditions underwent prospectively two-dimensional (2DE), real-time three-dimensional (RT3DE) echocardiography and cardiovascular magnetic resonance (CMR) exams within 4 h. Results The relationship between EDVCMR and EDV2DE and EDVRT3DE were strong (R 0.95 and 0.91). EDV index cut-offs for 2DE/RT3DE >87/104 ml/m(2) identified AR patients with severe regurgitation with a positive likelihood ratio (PLR) of 5.0/5.0. The corresponding in patients with MR EDV index cut-offs were >69/87 ml/m(2) with a PLR of 14.9/5.5. LV linear dimensions could not identify patients with severe regurgitation. Conclusions LV volumes by echocardiography can support the diagnosis of severe chronic regurgitation. Importantly, other causes for LV enlargement have to be considered.

Authors+Show Affiliations

a Department of Cardiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; b Department of Clinical Physiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; c Sahlgrenska University Hospital, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; d Heart Centre, King Faisal Specialist Hospital & Research Centre , Riyadh , Kingdom of Saudi Arabia ;a Department of Cardiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; c Sahlgrenska University Hospital, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ;e Department of Diagnostic Radiation Physics , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; f Department of Clinical Sciences , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ;f Department of Clinical Sciences , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; g Department of Radiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden.d Heart Centre, King Faisal Specialist Hospital & Research Centre , Riyadh , Kingdom of Saudi Arabia ;b Department of Clinical Physiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ; c Sahlgrenska University Hospital, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ;

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26822698

Citation

Bech-Hanssen, Odd, et al. "Left Ventricular Volumes By Echocardiography in Chronic Aortic and Mitral Regurgitations." Scandinavian Cardiovascular Journal : SCJ, vol. 50, no. 3, 2016, pp. 154-61.
Bech-Hanssen O, Polte CL, Lagerstrand KM, et al. Left ventricular volumes by echocardiography in chronic aortic and mitral regurgitations. Scand Cardiovasc J. 2016;50(3):154-61.
Bech-Hanssen, O., Polte, C. L., Lagerstrand, K. M., Johnsson, Å. A., Fadel, B. M., & Gao, S. A. (2016). Left ventricular volumes by echocardiography in chronic aortic and mitral regurgitations. Scandinavian Cardiovascular Journal : SCJ, 50(3), 154-61. https://doi.org/10.3109/14017431.2016.1148195
Bech-Hanssen O, et al. Left Ventricular Volumes By Echocardiography in Chronic Aortic and Mitral Regurgitations. Scand Cardiovasc J. 2016;50(3):154-61. PubMed PMID: 26822698.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Left ventricular volumes by echocardiography in chronic aortic and mitral regurgitations. AU - Bech-Hanssen,Odd, AU - Polte,Christian Lars, AU - Lagerstrand,Kerstin M, AU - Johnsson,Åse A, AU - Fadel,Bahaa M, AU - Gao,Sinsia A, Y1 - 2016/02/18/ PY - 2016/1/30/entrez PY - 2016/1/30/pubmed PY - 2017/3/30/medline KW - Aortic regurgitation KW - cardiovascular magnetic resonance KW - echocardiography KW - mitral regurgitation SP - 154 EP - 61 JF - Scandinavian cardiovascular journal : SCJ JO - Scand. Cardiovasc. J. VL - 50 IS - 3 N2 - Objectives Cut-off values for left ventricular (LV) dimensions indicating severe valve regurgitation have not been defined. The aim of this study was to establish echocardiographic cut-off values for LV dimensions indicating severe chronic aortic (AR) or mitral (MR) regurgitation. Design The hemodynamic significance was confirmed by documented reduction of end-diastolic volume (EDV) and symptom relief after surgery. Eighty-three patients with moderate or severe regurgitation (AR, n = 41; MR, n = 42) without other cardiac conditions underwent prospectively two-dimensional (2DE), real-time three-dimensional (RT3DE) echocardiography and cardiovascular magnetic resonance (CMR) exams within 4 h. Results The relationship between EDVCMR and EDV2DE and EDVRT3DE were strong (R 0.95 and 0.91). EDV index cut-offs for 2DE/RT3DE >87/104 ml/m(2) identified AR patients with severe regurgitation with a positive likelihood ratio (PLR) of 5.0/5.0. The corresponding in patients with MR EDV index cut-offs were >69/87 ml/m(2) with a PLR of 14.9/5.5. LV linear dimensions could not identify patients with severe regurgitation. Conclusions LV volumes by echocardiography can support the diagnosis of severe chronic regurgitation. Importantly, other causes for LV enlargement have to be considered. SN - 1651-2006 UR - https://www.unboundmedicine.com/medline/citation/26822698/Left_ventricular_volumes_by_echocardiography_in_chronic_aortic_and_mitral_regurgitations_ L2 - http://www.tandfonline.com/doi/full/10.3109/14017431.2016.1148195 DB - PRIME DP - Unbound Medicine ER -