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Factors associated with recovery from paraplegia in dogs with loss of pain perception in the pelvic limbs following intervertebral disk herniation.
J Am Vet Med Assoc. 2016 Feb 15; 248(4):386-94.JA

Abstract

OBJECTIVE

To investigate associations between recovery of locomotion and putative prognostic factors in dogs with loss of deep pain perception in the pelvic limbs caused by intervertebral disk herniation (IVDH).

DESIGN

Prospective cohort study.

ANIMALS

78 client-owned dogs evaluated for IVDH that underwent spinal decompression surgery.

PROCEDURES

Dogs with complete loss of deep pain perception in the pelvic limbs and tail underwent routine examinations, advanced imaging, and spinal decompression surgery in accordance with standards of practice and owner consent. For each dog, information was prospectively collected on duration of clinical signs prior to onset of paraplegia; delay between onset of paraplegia and initial referral evaluation; date of recovery of locomotion, death, or euthanasia (3-month follow-up period); and whether dogs had received corticosteroid drugs before surgery. Severity of spinal cord compression at the lesion epicenter was measured via CT or MRI.

RESULTS

45 of 78 (58%) of dogs recovered the ability to ambulate independently within 3 months after spinal decompression surgery. No evidence of prognostic value was identified for any of the investigated factors; importantly, a greater delay between onset of paraplegia and referral evaluation was not associated with a poorer prognosis.

CONCLUSIONS AND CLINICAL RELEVANCE

In this group of dogs with IVDH, immediacy of surgical treatment had no apparent association with outcome. The prognosis for recovery may instead be strongly influenced by the precise nature of the initiating injury.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

26829270

Citation

Jeffery, Nick D., et al. "Factors Associated With Recovery From Paraplegia in Dogs With Loss of Pain Perception in the Pelvic Limbs Following Intervertebral Disk Herniation." Journal of the American Veterinary Medical Association, vol. 248, no. 4, 2016, pp. 386-94.
Jeffery ND, Barker AK, Hu HZ, et al. Factors associated with recovery from paraplegia in dogs with loss of pain perception in the pelvic limbs following intervertebral disk herniation. J Am Vet Med Assoc. 2016;248(4):386-94.
Jeffery, N. D., Barker, A. K., Hu, H. Z., Alcott, C. J., Kraus, K. H., Scanlin, E. M., Granger, N., & Levine, J. M. (2016). Factors associated with recovery from paraplegia in dogs with loss of pain perception in the pelvic limbs following intervertebral disk herniation. Journal of the American Veterinary Medical Association, 248(4), 386-94. https://doi.org/10.2460/javma.248.4.386
Jeffery ND, et al. Factors Associated With Recovery From Paraplegia in Dogs With Loss of Pain Perception in the Pelvic Limbs Following Intervertebral Disk Herniation. J Am Vet Med Assoc. 2016 Feb 15;248(4):386-94. PubMed PMID: 26829270.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors associated with recovery from paraplegia in dogs with loss of pain perception in the pelvic limbs following intervertebral disk herniation. AU - Jeffery,Nick D, AU - Barker,Andrew K, AU - Hu,Hilary Z, AU - Alcott,Cody J, AU - Kraus,Karl H, AU - Scanlin,Elizabeth M, AU - Granger,Nicolas, AU - Levine,Jonathan M, PY - 2016/2/2/entrez PY - 2016/2/2/pubmed PY - 2016/10/25/medline SP - 386 EP - 94 JF - Journal of the American Veterinary Medical Association JO - J. Am. Vet. Med. Assoc. VL - 248 IS - 4 N2 - OBJECTIVE: To investigate associations between recovery of locomotion and putative prognostic factors in dogs with loss of deep pain perception in the pelvic limbs caused by intervertebral disk herniation (IVDH). DESIGN: Prospective cohort study. ANIMALS: 78 client-owned dogs evaluated for IVDH that underwent spinal decompression surgery. PROCEDURES: Dogs with complete loss of deep pain perception in the pelvic limbs and tail underwent routine examinations, advanced imaging, and spinal decompression surgery in accordance with standards of practice and owner consent. For each dog, information was prospectively collected on duration of clinical signs prior to onset of paraplegia; delay between onset of paraplegia and initial referral evaluation; date of recovery of locomotion, death, or euthanasia (3-month follow-up period); and whether dogs had received corticosteroid drugs before surgery. Severity of spinal cord compression at the lesion epicenter was measured via CT or MRI. RESULTS: 45 of 78 (58%) of dogs recovered the ability to ambulate independently within 3 months after spinal decompression surgery. No evidence of prognostic value was identified for any of the investigated factors; importantly, a greater delay between onset of paraplegia and referral evaluation was not associated with a poorer prognosis. CONCLUSIONS AND CLINICAL RELEVANCE: In this group of dogs with IVDH, immediacy of surgical treatment had no apparent association with outcome. The prognosis for recovery may instead be strongly influenced by the precise nature of the initiating injury. SN - 1943-569X UR - https://www.unboundmedicine.com/medline/citation/26829270/Factors_associated_with_recovery_from_paraplegia_in_dogs_with_loss_of_pain_perception_in_the_pelvic_limbs_following_intervertebral_disk_herniation_ L2 - http://avmajournals.avma.org/doi/full/10.2460/javma.248.4.386?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -