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[Macrocytic anemia].
Rev Prat. 1989 Oct 21; 39(24):2133-7.RP

Abstract

Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms). More rarely, these anaemias are associated with congenital deficiency of the enzymes involved in pyrimidine or purine biosynthesis. A few cases of thiamine-responsive megaloblastic anaemia have been reported. Some blood diseases may also associated with macrocytic anaemia. Finally, many drugs (antifolic agents, antipurine or antipyrimidine compounds) may induce macrocytic anaemia.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

2683003

Citation

Zittoun, J. "[Macrocytic Anemia]." La Revue Du Praticien, vol. 39, no. 24, 1989, pp. 2133-7.
Zittoun J. [Macrocytic anemia]. Rev Prat. 1989;39(24):2133-7.
Zittoun, J. (1989). [Macrocytic anemia]. La Revue Du Praticien, 39(24), 2133-7.
Zittoun J. [Macrocytic Anemia]. Rev Prat. 1989 Oct 21;39(24):2133-7. PubMed PMID: 2683003.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Macrocytic anemia]. A1 - Zittoun,J, PY - 1989/10/21/pubmed PY - 1989/10/21/medline PY - 1989/10/21/entrez SP - 2133 EP - 7 JF - La Revue du praticien JO - Rev Prat VL - 39 IS - 24 N2 - Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms). More rarely, these anaemias are associated with congenital deficiency of the enzymes involved in pyrimidine or purine biosynthesis. A few cases of thiamine-responsive megaloblastic anaemia have been reported. Some blood diseases may also associated with macrocytic anaemia. Finally, many drugs (antifolic agents, antipurine or antipyrimidine compounds) may induce macrocytic anaemia. SN - 0035-2640 UR - https://www.unboundmedicine.com/medline/citation/2683003/[Macrocytic_anemia]_ L2 - http://www.diseaseinfosearch.org/result/441 DB - PRIME DP - Unbound Medicine ER -
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