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Gastrointestinal Disorders in Cystic Fibrosis.
Clin Chest Med 2016; 37(1):109-18CC

Abstract

Gastrointestinal (GI) manifestations commonly complicate the care of patients with cystic fibrosis (CF). Despite recent approval of CF transmembrane conductance regulator modulating agents that can improve pulmonary function, GI disorders continue to be relevant and require innovative therapies. This article discusses the most common GI complications of CF, including reflux, pancreatic insufficiency, small bowel intestinal overgrowth, distal intestinal obstruction syndrome, and GI malignancy, with emphasis on clinical presentation and management.

Authors+Show Affiliations

Section of Digestive Diseases, Yale School of Medicine, 333 Cedar Street, 1080 LMP, New Haven, CT 06510, USA. Electronic address: david.assis@yale.edu.Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

26857772

Citation

Assis, David N., and Steven D. Freedman. "Gastrointestinal Disorders in Cystic Fibrosis." Clinics in Chest Medicine, vol. 37, no. 1, 2016, pp. 109-18.
Assis DN, Freedman SD. Gastrointestinal Disorders in Cystic Fibrosis. Clin Chest Med. 2016;37(1):109-18.
Assis, D. N., & Freedman, S. D. (2016). Gastrointestinal Disorders in Cystic Fibrosis. Clinics in Chest Medicine, 37(1), pp. 109-18. doi:10.1016/j.ccm.2015.11.004.
Assis DN, Freedman SD. Gastrointestinal Disorders in Cystic Fibrosis. Clin Chest Med. 2016;37(1):109-18. PubMed PMID: 26857772.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrointestinal Disorders in Cystic Fibrosis. AU - Assis,David N, AU - Freedman,Steven D, Y1 - 2015/12/24/ PY - 2016/2/10/entrez PY - 2016/2/10/pubmed PY - 2016/9/27/medline KW - Constipation KW - Cystic fibrosis KW - Distal intestinal obstruction syndrome KW - Dysmotility KW - Gastrointestinal malignancy KW - Pancreas insufficiency KW - Pancreatitis KW - Reflux SP - 109 EP - 18 JF - Clinics in chest medicine JO - Clin. Chest Med. VL - 37 IS - 1 N2 - Gastrointestinal (GI) manifestations commonly complicate the care of patients with cystic fibrosis (CF). Despite recent approval of CF transmembrane conductance regulator modulating agents that can improve pulmonary function, GI disorders continue to be relevant and require innovative therapies. This article discusses the most common GI complications of CF, including reflux, pancreatic insufficiency, small bowel intestinal overgrowth, distal intestinal obstruction syndrome, and GI malignancy, with emphasis on clinical presentation and management. SN - 1557-8216 UR - https://www.unboundmedicine.com/medline/citation/26857772/Gastrointestinal_Disorders_in_Cystic_Fibrosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0272-5231(15)00143-4 DB - PRIME DP - Unbound Medicine ER -