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PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013.
Southeast Asian J Trop Med Public Health. 2015 Nov; 46(6):1013-20.SA

Abstract

Human enterovirus (EV) infection causes hand, foot, and mouth disease (HFMD) and herpangina (HA). We studied the prevalence of enterovirus (EV) among patients with HFMD and HA in Thailand during 2013. We conducted a study in archived specimens of patients sent for screening for enterovirus. A total of 203 clinical specimens from 184 individuals with painful blister in the oropharynx and on the palms, soles, knees, elbows or buttock were examined by semi-nested polymerase chain reaction (PCR) for the 5'UTR and VP1 genes of EV. Eighty-six samples were positive: EV71 was detected in 14 (30%), CV-A8 in 12 (26%) and CV-A16 in 10 (21%). Classification of EV species detected revealed that 46 specimens were EV-A, 14 specimens were EV-B, 1 specimen was EV-D, and 16 specimens were positive for unclassified enterovirus. The majority of individuals with EV infection were aged 2-6 years. Multiple EV-A serotypes were detected among HFMD and HA patients in our study.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26867359

Citation

Mauleekoonphairoj, John, et al. "PREVALENCE of HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, and MOUTH DISEASE and HERPANGINA in THAILAND, 2013." The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 46, no. 6, 2015, pp. 1013-20.
Mauleekoonphairoj J, Puenpa J, Korkong S, et al. PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013. Southeast Asian J Trop Med Public Health. 2015;46(6):1013-20.
Mauleekoonphairoj, J., Puenpa, J., Korkong, S., Vongpunsawad, S., & Poovorawan, Y. (2015). PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013. The Southeast Asian Journal of Tropical Medicine and Public Health, 46(6), 1013-20.
Mauleekoonphairoj J, et al. PREVALENCE of HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, and MOUTH DISEASE and HERPANGINA in THAILAND, 2013. Southeast Asian J Trop Med Public Health. 2015;46(6):1013-20. PubMed PMID: 26867359.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013. AU - Mauleekoonphairoj,John, AU - Puenpa,Jiratchaya, AU - Korkong,Sumeth, AU - Vongpunsawad,Sompong, AU - Poovorawan,Yong, PY - 2016/2/13/entrez PY - 2016/2/13/pubmed PY - 2016/4/22/medline SP - 1013 EP - 20 JF - The Southeast Asian journal of tropical medicine and public health JO - Southeast Asian J Trop Med Public Health VL - 46 IS - 6 N2 - Human enterovirus (EV) infection causes hand, foot, and mouth disease (HFMD) and herpangina (HA). We studied the prevalence of enterovirus (EV) among patients with HFMD and HA in Thailand during 2013. We conducted a study in archived specimens of patients sent for screening for enterovirus. A total of 203 clinical specimens from 184 individuals with painful blister in the oropharynx and on the palms, soles, knees, elbows or buttock were examined by semi-nested polymerase chain reaction (PCR) for the 5'UTR and VP1 genes of EV. Eighty-six samples were positive: EV71 was detected in 14 (30%), CV-A8 in 12 (26%) and CV-A16 in 10 (21%). Classification of EV species detected revealed that 46 specimens were EV-A, 14 specimens were EV-B, 1 specimen was EV-D, and 16 specimens were positive for unclassified enterovirus. The majority of individuals with EV infection were aged 2-6 years. Multiple EV-A serotypes were detected among HFMD and HA patients in our study. SN - 0125-1562 UR - https://www.unboundmedicine.com/medline/citation/26867359/PREVALENCE_OF_HUMAN_ENTEROVIRUS_AMONG_PATIENTS_WITH_HAND_FOOT_AND_MOUTH_DISEASE_AND_HERPANGINA_IN_THAILAND_2013_ DB - PRIME DP - Unbound Medicine ER -