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Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients.
J Trop Pediatr. 2016 08; 62(4):328-30.JT

Abstract

Diagnosis of Burkholderia pseudomallei pneumonia in children is challenging. We investigated the utility of nasopharyngeal swabs taken from 194 paediatric patients on admission with radiologically proven pneumonia. Melioidosis was proven in 0.5% of samples tested and only in a third of those known to be bacteraemic with B. pseudomallei. It appears unlikely that culture of nasopharyngeal secretions is helpful to confirm B. pseudomallei pneumonia in paediatric patients.

Authors+Show Affiliations

Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia pascohearn@hotmail.com.Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Angkor Hospital for Children, Siem Reap, Cambodia.Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia.Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Angkor Hospital for Children, Siem Reap, Cambodia.Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26874977

Citation

Hearn, Pasco, et al. "Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia Pseudomallei Pneumonia in Paediatric Patients." Journal of Tropical Pediatrics, vol. 62, no. 4, 2016, pp. 328-30.
Hearn P, Turner C, Suy K, et al. Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients. J Trop Pediatr. 2016;62(4):328-30.
Hearn, P., Turner, C., Suy, K., Soeng, S., Day, N. P., & Turner, P. (2016). Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients. Journal of Tropical Pediatrics, 62(4), 328-30. https://doi.org/10.1093/tropej/fmv109
Hearn P, et al. Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia Pseudomallei Pneumonia in Paediatric Patients. J Trop Pediatr. 2016;62(4):328-30. PubMed PMID: 26874977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients. AU - Hearn,Pasco, AU - Turner,Claudia, AU - Suy,Kuong, AU - Soeng,Sona, AU - Day,Nicholas P J, AU - Turner,Paul, Y1 - 2016/02/13/ PY - 2016/2/15/entrez PY - 2016/2/15/pubmed PY - 2017/8/10/medline KW - Burkholderia pseudomallei KW - melioidosis KW - nasopharyngeal swab KW - paediatric SP - 328 EP - 30 JF - Journal of tropical pediatrics JO - J Trop Pediatr VL - 62 IS - 4 N2 - Diagnosis of Burkholderia pseudomallei pneumonia in children is challenging. We investigated the utility of nasopharyngeal swabs taken from 194 paediatric patients on admission with radiologically proven pneumonia. Melioidosis was proven in 0.5% of samples tested and only in a third of those known to be bacteraemic with B. pseudomallei. It appears unlikely that culture of nasopharyngeal secretions is helpful to confirm B. pseudomallei pneumonia in paediatric patients. SN - 1465-3664 UR - https://www.unboundmedicine.com/medline/citation/26874977/Lack_of_Utility_of_Nasopharyngeal_Swabs_for_Diagnosis_of_Burkholderia_pseudomallei_Pneumonia_in_Paediatric_Patients_ L2 - https://academic.oup.com/tropej/article-lookup/doi/10.1093/tropej/fmv109 DB - PRIME DP - Unbound Medicine ER -