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Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update.
Mycopathologia. 2016 Aug; 181(7-8):547-53.M

Abstract

Dermatophytosis is among the most common superficial mycoses in Iran. The purpose of this report was to update the clinical and mycological features of human dermatophytosis in the Khuzestan, southwestern Iran. In the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. Strains isolated from cultures were subjected to amplification of the nuclear rDNA ITS regions in a PCR assay followed by an early established RFLP analysis. For confirmation of species identification, 100 isolates as representatives of all presumable species were subjected to ITS sequencing. Infection was confirmed in 1123 individuals (27.25 %) in the age range of 1-89 years by direct microscopy and/or culture including 603 males versus 520 females. Frequencies of infections were the highest and the lowest in age groups of 21-30 and 11-20 years, respectively. Tinea corporis was the most prevalent clinical manifestation followed by tinea cruris, tinea capitis, tinea manuum, tinea pedis, tinea unguium, tinea faciei and tinea barbae. Trichophyton interdigitale (58.7 %) was the most dominant isolate followed by Epidermophyton floccosum (35.4 %), Microsporum canis (3 %), T. rubrum (1.5 %), T. species of Arthroderma benhamiae (0.5 %), T. tonsurans (0.3 %) and T. violaceum (0.3 %). Other species included M. gypseum, M. fulvum and T. verrucosum (each one 0.1 %). Such a high occurrence of infection with T. interdigitale, which has not been reported from Iran, is due to the use of accurate molecular methods based on new species concept in dermatophytes. The prevalence of dermatophytoses caused by zoophilic species remarkably increased and Trichophyton species of A. benhamiae has emerged as a new agent of dermatophytosis in southwestern Iran, while infections due to anthropophilic species, except E. floccosum, took a decreasing trend.

Authors+Show Affiliations

Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. a.r.matehkolaie@gmail.com. Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. a.r.matehkolaie@gmail.com.Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Department of Medical Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Laboratory of Space and Environmental Medicine, Graduate School of Medicine, Teikyo University, Tokyo, Japan.Consiliary Laboratory for Dermatophytes, Institute of Microbiology, Charité-Universitätsmedizin Berlin, Dorotheenstrasse 96, Berlin, Germany.Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Abadan School of Medical sciences, Abadan, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26886443

Citation

Rezaei-Matehkolaei, Ali, et al. "Epidemiological Aspects of Dermatophytosis in Khuzestan, Southwestern Iran, an Update." Mycopathologia, vol. 181, no. 7-8, 2016, pp. 547-53.
Rezaei-Matehkolaei A, Rafiei A, Makimura K, et al. Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update. Mycopathologia. 2016;181(7-8):547-53.
Rezaei-Matehkolaei, A., Rafiei, A., Makimura, K., Gräser, Y., Gharghani, M., & Sadeghi-Nejad, B. (2016). Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update. Mycopathologia, 181(7-8), 547-53. https://doi.org/10.1007/s11046-016-9990-x
Rezaei-Matehkolaei A, et al. Epidemiological Aspects of Dermatophytosis in Khuzestan, Southwestern Iran, an Update. Mycopathologia. 2016;181(7-8):547-53. PubMed PMID: 26886443.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiological Aspects of Dermatophytosis in Khuzestan, southwestern Iran, an Update. AU - Rezaei-Matehkolaei,Ali, AU - Rafiei,Abdollah, AU - Makimura,Koichi, AU - Gräser,Yvonne, AU - Gharghani,Maral, AU - Sadeghi-Nejad,Batool, Y1 - 2016/02/17/ PY - 2015/09/19/received PY - 2016/02/01/accepted PY - 2016/2/18/entrez PY - 2016/2/18/pubmed PY - 2017/4/4/medline KW - Dermatophyte KW - Epidemiology KW - ITS KW - Khuzestan KW - Tinea SP - 547 EP - 53 JF - Mycopathologia JO - Mycopathologia VL - 181 IS - 7-8 N2 - Dermatophytosis is among the most common superficial mycoses in Iran. The purpose of this report was to update the clinical and mycological features of human dermatophytosis in the Khuzestan, southwestern Iran. In the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. Strains isolated from cultures were subjected to amplification of the nuclear rDNA ITS regions in a PCR assay followed by an early established RFLP analysis. For confirmation of species identification, 100 isolates as representatives of all presumable species were subjected to ITS sequencing. Infection was confirmed in 1123 individuals (27.25 %) in the age range of 1-89 years by direct microscopy and/or culture including 603 males versus 520 females. Frequencies of infections were the highest and the lowest in age groups of 21-30 and 11-20 years, respectively. Tinea corporis was the most prevalent clinical manifestation followed by tinea cruris, tinea capitis, tinea manuum, tinea pedis, tinea unguium, tinea faciei and tinea barbae. Trichophyton interdigitale (58.7 %) was the most dominant isolate followed by Epidermophyton floccosum (35.4 %), Microsporum canis (3 %), T. rubrum (1.5 %), T. species of Arthroderma benhamiae (0.5 %), T. tonsurans (0.3 %) and T. violaceum (0.3 %). Other species included M. gypseum, M. fulvum and T. verrucosum (each one 0.1 %). Such a high occurrence of infection with T. interdigitale, which has not been reported from Iran, is due to the use of accurate molecular methods based on new species concept in dermatophytes. The prevalence of dermatophytoses caused by zoophilic species remarkably increased and Trichophyton species of A. benhamiae has emerged as a new agent of dermatophytosis in southwestern Iran, while infections due to anthropophilic species, except E. floccosum, took a decreasing trend. SN - 1573-0832 UR - https://www.unboundmedicine.com/medline/citation/26886443/Epidemiological_Aspects_of_Dermatophytosis_in_Khuzestan_southwestern_Iran_an_Update_ L2 - https://dx.doi.org/10.1007/s11046-016-9990-x DB - PRIME DP - Unbound Medicine ER -