Tags

Type your tag names separated by a space and hit enter

Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-o-phenylenediamine induced mutagenesis in Salmonella typhimurium.
Indian J Exp Biol. 1989 Mar; 27(3):207-9.IJ

Abstract

Water, acetone and chloroform extracts of E. officinalis fruit reduced sodium azide and NPD induced his+ revertants significantly in TA100 and TA97 a strains respectively of S. typhimurium. The chloroform extract was less active as compared to water and acetone extracts. Autoclaving of water extract for 15 min did not reduce its activity. The enhanced inhibitory activity of the extracts on pre-incubation suggests the possibility of desmutagens in the extracts. Besides ascorbic acid, a constituent of the extract, the role of other antimutagenic factors in the extract cannot be ruled out.

Authors

Grover IS
No affiliation info available
Kaur S
No affiliation info available

MeSH

AzidesCarcinogensFruitMutagenicity TestsMutationPhenylenediaminesPlant ExtractsSalmonella typhimuriumSodium Azide

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2691399

Citation

Grover, I S., and S Kaur. "Effect of Emblica Officinalis Gaertn. (Indian Gooseberry) Fruit Extract On Sodium Azide and 4-nitro-o-phenylenediamine Induced Mutagenesis in Salmonella Typhimurium." Indian Journal of Experimental Biology, vol. 27, no. 3, 1989, pp. 207-9.
Grover IS, Kaur S. Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-o-phenylenediamine induced mutagenesis in Salmonella typhimurium. Indian J Exp Biol. 1989;27(3):207-9.
Grover, I. S., & Kaur, S. (1989). Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-o-phenylenediamine induced mutagenesis in Salmonella typhimurium. Indian Journal of Experimental Biology, 27(3), 207-9.
Grover IS, Kaur S. Effect of Emblica Officinalis Gaertn. (Indian Gooseberry) Fruit Extract On Sodium Azide and 4-nitro-o-phenylenediamine Induced Mutagenesis in Salmonella Typhimurium. Indian J Exp Biol. 1989;27(3):207-9. PubMed PMID: 2691399.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-o-phenylenediamine induced mutagenesis in Salmonella typhimurium. AU - Grover,I S, AU - Kaur,S, PY - 1989/3/1/pubmed PY - 1989/3/1/medline PY - 1989/3/1/entrez SP - 207 EP - 9 JF - Indian journal of experimental biology JO - Indian J Exp Biol VL - 27 IS - 3 N2 - Water, acetone and chloroform extracts of E. officinalis fruit reduced sodium azide and NPD induced his+ revertants significantly in TA100 and TA97 a strains respectively of S. typhimurium. The chloroform extract was less active as compared to water and acetone extracts. Autoclaving of water extract for 15 min did not reduce its activity. The enhanced inhibitory activity of the extracts on pre-incubation suggests the possibility of desmutagens in the extracts. Besides ascorbic acid, a constituent of the extract, the role of other antimutagenic factors in the extract cannot be ruled out. SN - 0019-5189 UR - https://www.unboundmedicine.com/medline/citation/2691399/Effect_of_Emblica_officinalis_Gaertn___Indian_gooseberry__fruit_extract_on_sodium_azide_and_4_nitro_o_phenylenediamine_induced_mutagenesis_in_Salmonella_typhimurium_ DB - PRIME DP - Unbound Medicine ER -