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Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015.
Ann Lab Med. 2016 May; 36(3):203-8.AL

Abstract

For two months between May and July 2015, a nationwide outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) occurred in Korea. On June 3, 2015, the Korean Society for Laboratory Medicine (KSLM) launched a MERS-CoV Laboratory Response Task Force (LR-TF) to facilitate clinical laboratories to set up the diagnosis of MERS-CoV infection. Based on the WHO interim recommendations, the Centers for Disease Control and Prevention of United States guidelines for MERS-CoV laboratory testing, and other available resources, the KSLM MERS-CoV LR-TF provided the first version of the laboratory practice guidelines for the molecular diagnosis of MERS-CoV to the clinical laboratories on June 12, 2015. The guidelines described here are an updated version that includes case definition, indications for testing, specimen type and protocols for specimen collection, specimen packing and transport, specimen handling and nucleic acid extraction, molecular detection of MERS-CoV, interpretation of results and reporting, and laboratory safety. The KSLM guidelines mainly focus on the molecular diagnosis of MERS-CoV, reflecting the unique situation in Korea and the state of knowledge at the time of publication.

Authors+Show Affiliations

Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Laboratory Medicine, Catholic Kwandong University College of Medicine, Incheon, Korea.Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. mnkim@amc.seoul.kr.Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.No affiliation info available

Pub Type(s)

Journal Article
Practice Guideline
Review

Language

eng

PubMed ID

26915607

Citation

Ki, Chang Seok, et al. "Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015." Annals of Laboratory Medicine, vol. 36, no. 3, 2016, pp. 203-8.
Ki CS, Lee H, Sung H, et al. Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015. Ann Lab Med. 2016;36(3):203-8.
Ki, C. S., Lee, H., Sung, H., Kim, S., Seong, M. W., Yong, D., Kim, J. S., Lee, M. K., Kim, M. N., Choi, J. R., & Kim, J. H. (2016). Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015. Annals of Laboratory Medicine, 36(3), 203-8. https://doi.org/10.3343/alm.2016.36.3.203
Ki CS, et al. Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015. Ann Lab Med. 2016;36(3):203-8. PubMed PMID: 26915607.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Korean Society for Laboratory Medicine Practice Guidelines for the Molecular Diagnosis of Middle East Respiratory Syndrome During an Outbreak in Korea in 2015. AU - Ki,Chang Seok, AU - Lee,Hyukmin, AU - Sung,Heungsup, AU - Kim,Sinyoung, AU - Seong,Moon Woo, AU - Yong,Dongeun, AU - Kim,Jae Seok, AU - Lee,Mi Kyung, AU - Kim,Mi Na, AU - Choi,Jong Rak, AU - Kim,Jeong Ho, AU - ,, PY - 2015/08/31/received PY - 2015/11/13/revised PY - 2016/01/29/accepted PY - 2016/2/27/entrez PY - 2016/2/27/pubmed PY - 2017/1/10/medline KW - Guidelines KW - Middle East respiratory syndrome coronavirus KW - Molecular diagnosis KW - Outbreak SP - 203 EP - 8 JF - Annals of laboratory medicine JO - Ann Lab Med VL - 36 IS - 3 N2 - For two months between May and July 2015, a nationwide outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) occurred in Korea. On June 3, 2015, the Korean Society for Laboratory Medicine (KSLM) launched a MERS-CoV Laboratory Response Task Force (LR-TF) to facilitate clinical laboratories to set up the diagnosis of MERS-CoV infection. Based on the WHO interim recommendations, the Centers for Disease Control and Prevention of United States guidelines for MERS-CoV laboratory testing, and other available resources, the KSLM MERS-CoV LR-TF provided the first version of the laboratory practice guidelines for the molecular diagnosis of MERS-CoV to the clinical laboratories on June 12, 2015. The guidelines described here are an updated version that includes case definition, indications for testing, specimen type and protocols for specimen collection, specimen packing and transport, specimen handling and nucleic acid extraction, molecular detection of MERS-CoV, interpretation of results and reporting, and laboratory safety. The KSLM guidelines mainly focus on the molecular diagnosis of MERS-CoV, reflecting the unique situation in Korea and the state of knowledge at the time of publication. SN - 2234-3814 UR - https://www.unboundmedicine.com/medline/citation/26915607/Korean_Society_for_Laboratory_Medicine_Practice_Guidelines_for_the_Molecular_Diagnosis_of_Middle_East_Respiratory_Syndrome_During_an_Outbreak_in_Korea_in_2015_ L2 - http://www.annlabmed.org/journal/viewJournal.html?year=2016&vol=36&page=203 DB - PRIME DP - Unbound Medicine ER -