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Progress Toward Eliminating Hepatitis A Disease in the United States.
MMWR Suppl. 2016 Feb 12; 65(1):29-41.MS

Abstract

Hepatitis A virus (HAV) disease disproportionately affects adolescents and young adults, American Indian/Alaska Native and Hispanic racial/ethnic groups, and disadvantaged populations. During 1996-2006, the Advisory Committee on Immunization Practices (ACIP) made incremental changes in hepatitis A (HepA) vaccination recommendations to increase coverage for children and persons at high risk for HAV infection. This report examines the temporal association of ACIP-recommended HepA vaccination and disparities (on the absolute scale) in cases of HAV disease and on seroprevalence of HAV-related protection (measured as antibody to HAV [anti-HAV]). ACIP-recommended childhood HepA vaccination in the United States has eliminated most absolute disparities in HAV disease by age, race/ethnicity, and geographic area with relatively modest ≥1-dose and ≥2-dose vaccine coverage. However, the increasing proportion of cases of HAV disease among adults with identified and unidentified sources of exposure underscores the importance of considering new strategies for preventing HAV infection among U.S. adults. For continued progress to be made toward elimination of HAV disease in the United States, additional strategies are needed to prevent HAV infection among an emerging population of susceptible adults. Notably, HAV infection remains endemic in much of the world, contributing to U.S. cases through international travel and the global food economy.

Authors+Show Affiliations

Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26916458

Citation

Murphy, Trudy V., et al. "Progress Toward Eliminating Hepatitis a Disease in the United States." MMWR Supplements, vol. 65, no. 1, 2016, pp. 29-41.
Murphy TV, Denniston MM, Hill HA, et al. Progress Toward Eliminating Hepatitis A Disease in the United States. MMWR Suppl. 2016;65(1):29-41.
Murphy, T. V., Denniston, M. M., Hill, H. A., McDonald, M., Klevens, M. R., Elam-Evans, L. D., Nelson, N. P., Iskander, J., & Ward, J. D. (2016). Progress Toward Eliminating Hepatitis A Disease in the United States. MMWR Supplements, 65(1), 29-41. https://doi.org/10.15585/mmwr.su6501a6
Murphy TV, et al. Progress Toward Eliminating Hepatitis a Disease in the United States. MMWR Suppl. 2016 Feb 12;65(1):29-41. PubMed PMID: 26916458.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Progress Toward Eliminating Hepatitis A Disease in the United States. AU - Murphy,Trudy V, AU - Denniston,Maxine M, AU - Hill,Holly A, AU - McDonald,Marian, AU - Klevens,Monina R, AU - Elam-Evans,Laurie D, AU - Nelson,Noele P, AU - Iskander,John, AU - Ward,John D, Y1 - 2016/02/12/ PY - 2016/2/27/entrez PY - 2016/2/27/pubmed PY - 2016/7/7/medline SP - 29 EP - 41 JF - MMWR supplements JO - MMWR Suppl VL - 65 IS - 1 N2 - Hepatitis A virus (HAV) disease disproportionately affects adolescents and young adults, American Indian/Alaska Native and Hispanic racial/ethnic groups, and disadvantaged populations. During 1996-2006, the Advisory Committee on Immunization Practices (ACIP) made incremental changes in hepatitis A (HepA) vaccination recommendations to increase coverage for children and persons at high risk for HAV infection. This report examines the temporal association of ACIP-recommended HepA vaccination and disparities (on the absolute scale) in cases of HAV disease and on seroprevalence of HAV-related protection (measured as antibody to HAV [anti-HAV]). ACIP-recommended childhood HepA vaccination in the United States has eliminated most absolute disparities in HAV disease by age, race/ethnicity, and geographic area with relatively modest ≥1-dose and ≥2-dose vaccine coverage. However, the increasing proportion of cases of HAV disease among adults with identified and unidentified sources of exposure underscores the importance of considering new strategies for preventing HAV infection among U.S. adults. For continued progress to be made toward elimination of HAV disease in the United States, additional strategies are needed to prevent HAV infection among an emerging population of susceptible adults. Notably, HAV infection remains endemic in much of the world, contributing to U.S. cases through international travel and the global food economy. SN - 2380-8942 UR - https://www.unboundmedicine.com/medline/citation/26916458/Progress_Toward_Eliminating_Hepatitis_A_Disease_in_the_United_States_ L2 - http://www.diseaseinfosearch.org/result/3332 DB - PRIME DP - Unbound Medicine ER -