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[Incidence and symptoms of cow's milk protein intolerance following acute gastroenteritis in young infants. Effect of a hypoallergenic diet].
Monatsschr Kinderheilkd. 1989 Nov; 137(11):747-51.MK

Abstract

In a prospective randomized study we investigated in 28 mainly bottle-fed infants younger than 60 days whether in acute gastroenteritis a hypoallergenic formula could prevent the development of cow's milk protein intolerance. Group 1 (14 infants) was fed with a formula adapted to human milk, Group 2 (14 infants) got a semi-elementary formula (Alfaré). After 3 months group II was exposed to cow's milk protein with a standardized challenge and the incidence of CMPI in both groups was calculated. All cases with the acute form of CMPI occurred in group II (5/12) whereas in group I only one infant suffered from the protracted mild form of the disease. Inspite of the relatively small number of probands we conclude from our results that in infants who are not totally breast-fed in the post-enteritic period feeding with a formula adapted to human milk is preferable to hypoallergenic semi-elementary preparations. An allergen free period of 3 months seems to induce symptoms of cow's milk intolerance, probably as a booster-effect to early sensibilisation.

Authors+Show Affiliations

Wolf A
Abteilung II, Universitäts-Kinderklinik Ulm.
Leupold D
No affiliation info available
Bürgin-Wolff A
No affiliation info available
Kohne E
No affiliation info available

MeSH

AnimalsCattleFemaleFollow-Up StudiesFood HypersensitivityFood, FormulatedGastroenteritisHumansInfantInfant, NewbornMaleMilk ProteinsPilot ProjectsProspective StudiesRandomized Controlled Trials as Topic

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial

Language

ger

PubMed ID

2691885

Citation

Wolf, A, et al. "[Incidence and Symptoms of Cow's Milk Protein Intolerance Following Acute Gastroenteritis in Young Infants. Effect of a Hypoallergenic Diet]." Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde, vol. 137, no. 11, 1989, pp. 747-51.
Wolf A, Leupold D, Bürgin-Wolff A, et al. [Incidence and symptoms of cow's milk protein intolerance following acute gastroenteritis in young infants. Effect of a hypoallergenic diet]. Monatsschr Kinderheilkd. 1989;137(11):747-51.
Wolf, A., Leupold, D., Bürgin-Wolff, A., & Kohne, E. (1989). [Incidence and symptoms of cow's milk protein intolerance following acute gastroenteritis in young infants. Effect of a hypoallergenic diet]. Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde, 137(11), 747-51.
Wolf A, et al. [Incidence and Symptoms of Cow's Milk Protein Intolerance Following Acute Gastroenteritis in Young Infants. Effect of a Hypoallergenic Diet]. Monatsschr Kinderheilkd. 1989;137(11):747-51. PubMed PMID: 2691885.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Incidence and symptoms of cow's milk protein intolerance following acute gastroenteritis in young infants. Effect of a hypoallergenic diet]. AU - Wolf,A, AU - Leupold,D, AU - Bürgin-Wolff,A, AU - Kohne,E, PY - 1989/11/1/pubmed PY - 1989/11/1/medline PY - 1989/11/1/entrez SP - 747 EP - 51 JF - Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde JO - Monatsschr Kinderheilkd VL - 137 IS - 11 N2 - In a prospective randomized study we investigated in 28 mainly bottle-fed infants younger than 60 days whether in acute gastroenteritis a hypoallergenic formula could prevent the development of cow's milk protein intolerance. Group 1 (14 infants) was fed with a formula adapted to human milk, Group 2 (14 infants) got a semi-elementary formula (Alfaré). After 3 months group II was exposed to cow's milk protein with a standardized challenge and the incidence of CMPI in both groups was calculated. All cases with the acute form of CMPI occurred in group II (5/12) whereas in group I only one infant suffered from the protracted mild form of the disease. Inspite of the relatively small number of probands we conclude from our results that in infants who are not totally breast-fed in the post-enteritic period feeding with a formula adapted to human milk is preferable to hypoallergenic semi-elementary preparations. An allergen free period of 3 months seems to induce symptoms of cow's milk intolerance, probably as a booster-effect to early sensibilisation. SN - 0026-9298 UR - https://www.unboundmedicine.com/medline/citation/2691885/[Incidence_and_symptoms_of_cow's_milk_protein_intolerance_following_acute_gastroenteritis_in_young_infants__Effect_of_a_hypoallergenic_diet]_ DB - PRIME DP - Unbound Medicine ER -