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Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition.
Clin Nutr. 2016 12; 35(6):1557-1563.CN

Abstract

BACKGROUND

The reported prevalence of sarcopenia ranges widely depending on its definition criterion. European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria. This definition recommends using normative data of the study population rather than other reference populations.

OBJECTIVE

We aimed to define the reference cut-off values for muscle mass, muscle strength and calf circumference in Turkey in order to improve general applicability of EWGSOP criteria.

MATERIAL AND METHODS

Healthy young adults between 18 and 39 years of age with no known chronic disease or chronic drug usage were included in our study to serve as reference population for assessing muscle mass. Community-dwelling older outpatients were prospectively recruited from the geriatrics outpatient clinics of a university hospital for assessing hand grip strength and calf circumference. Body composition was assessed by bioimpedance analysis. Muscle strength was assessed measuring hand grip strength with a Jamar hand dynamometer. The cut-off thresholds for muscle mass were defined as the mean-2SD of the values of the young reference study population; for grip strength were calculated from ROC analyses using cut-off values that predicted gait speed < 0.8 m/s; and for calf circumference were calculated from ROC analyses using cut-off values that predicted low muscle mass.

RESULTS

The young reference group included a total of 301 participants (187 male, 114 female; mean age: 26.5 ± 4.6 years). The cut-off thresholds for skeletal muscle mass indexes were 9.2 kg/m2 and 7.4 kg/m2 in males and females, respectively. The older community dwelling group included 406 subjects (123 male, 283 female, mean age: 76.6 ± 6.7 years). The cut-off thresholds for hand grip strength were 32 kg and 22 kg for males and females. The cut-off threshold for calf circumference was 33 cm for both males and females.

CONCLUSIONS

The cut-off thresholds for muscle mass, grip strength and calf circumference were somewhat higher but comparable with other reference populations. Further worldwide studies from different nations and countries are needed to obtain better reference values.

Authors+Show Affiliations

Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey. Electronic address: gbahatozturk@yahoo.com.Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Capa, 34390 Istanbul, Turkey.Servicio de Geriatría, Hospital Universitario Ramón y Cajal, Madrid, Spain.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26922142

Citation

Bahat, Gulistan, et al. "Cut-off Points to Identify Sarcopenia According to European Working Group On Sarcopenia in Older People (EWGSOP) Definition." Clinical Nutrition (Edinburgh, Scotland), vol. 35, no. 6, 2016, pp. 1557-1563.
Bahat G, Tufan A, Tufan F, et al. Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition. Clin Nutr. 2016;35(6):1557-1563.
Bahat, G., Tufan, A., Tufan, F., Kilic, C., Akpinar, T. S., Kose, M., Erten, N., Karan, M. A., & Cruz-Jentoft, A. J. (2016). Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition. Clinical Nutrition (Edinburgh, Scotland), 35(6), 1557-1563. https://doi.org/10.1016/j.clnu.2016.02.002
Bahat G, et al. Cut-off Points to Identify Sarcopenia According to European Working Group On Sarcopenia in Older People (EWGSOP) Definition. Clin Nutr. 2016;35(6):1557-1563. PubMed PMID: 26922142.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cut-off points to identify sarcopenia according to European Working Group on Sarcopenia in Older People (EWGSOP) definition. AU - Bahat,Gulistan, AU - Tufan,Asli, AU - Tufan,Fatih, AU - Kilic,Cihan, AU - Akpinar,Timur Selçuk, AU - Kose,Murat, AU - Erten,Nilgun, AU - Karan,Mehmet Akif, AU - Cruz-Jentoft,Alfonso J, Y1 - 2016/02/11/ PY - 2015/05/26/received PY - 2015/10/15/revised PY - 2016/02/04/accepted PY - 2016/2/29/pubmed PY - 2018/1/19/medline PY - 2016/2/29/entrez KW - Cut-off KW - EWGSOP KW - Reference KW - Sarcopenia SP - 1557 EP - 1563 JF - Clinical nutrition (Edinburgh, Scotland) JO - Clin Nutr VL - 35 IS - 6 N2 - BACKGROUND: The reported prevalence of sarcopenia ranges widely depending on its definition criterion. European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria. This definition recommends using normative data of the study population rather than other reference populations. OBJECTIVE: We aimed to define the reference cut-off values for muscle mass, muscle strength and calf circumference in Turkey in order to improve general applicability of EWGSOP criteria. MATERIAL AND METHODS: Healthy young adults between 18 and 39 years of age with no known chronic disease or chronic drug usage were included in our study to serve as reference population for assessing muscle mass. Community-dwelling older outpatients were prospectively recruited from the geriatrics outpatient clinics of a university hospital for assessing hand grip strength and calf circumference. Body composition was assessed by bioimpedance analysis. Muscle strength was assessed measuring hand grip strength with a Jamar hand dynamometer. The cut-off thresholds for muscle mass were defined as the mean-2SD of the values of the young reference study population; for grip strength were calculated from ROC analyses using cut-off values that predicted gait speed < 0.8 m/s; and for calf circumference were calculated from ROC analyses using cut-off values that predicted low muscle mass. RESULTS: The young reference group included a total of 301 participants (187 male, 114 female; mean age: 26.5 ± 4.6 years). The cut-off thresholds for skeletal muscle mass indexes were 9.2 kg/m2 and 7.4 kg/m2 in males and females, respectively. The older community dwelling group included 406 subjects (123 male, 283 female, mean age: 76.6 ± 6.7 years). The cut-off thresholds for hand grip strength were 32 kg and 22 kg for males and females. The cut-off threshold for calf circumference was 33 cm for both males and females. CONCLUSIONS: The cut-off thresholds for muscle mass, grip strength and calf circumference were somewhat higher but comparable with other reference populations. Further worldwide studies from different nations and countries are needed to obtain better reference values. SN - 1532-1983 UR - https://www.unboundmedicine.com/medline/citation/26922142/Cut_off_points_to_identify_sarcopenia_according_to_European_Working_Group_on_Sarcopenia_in_Older_People__EWGSOP__definition_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0261-5614(16)00058-3 DB - PRIME DP - Unbound Medicine ER -