Citation
Vazquez-Perez, Joel A., et al. "EV-D68 Infection in Children With Asthma Exacerbation and Pneumonia in Mexico City During 2014 Autumn." Influenza and Other Respiratory Viruses, vol. 10, no. 3, 2016, pp. 154-60.
Vazquez-Perez JA, Ramirez-Gonzalez JE, Moreno-Valencia Y, et al. EV-D68 infection in children with asthma exacerbation and pneumonia in Mexico City during 2014 autumn. Influenza Other Respir Viruses. 2016;10(3):154-60.
Vazquez-Perez, J. A., Ramirez-Gonzalez, J. E., Moreno-Valencia, Y., Hernandez-Hernandez, V. A., Romero-Espinoza, J. A., Castillejos-Lopez, M., Hernandez, A., Perez-Padilla, R., Oropeza-Lopez, L. E., Escobar-Escamilla, N., Gonzalez-Villa, M., Alejandre-Garcia, A., Regalado-Pineda, J., Santillan-Doherty, P., Lopez-Martínez, I., Diaz-Quiñonez, A., & Salas-Hernandez, J. (2016). EV-D68 infection in children with asthma exacerbation and pneumonia in Mexico City during 2014 autumn. Influenza and Other Respiratory Viruses, 10(3), 154-60. https://doi.org/10.1111/irv.12384
Vazquez-Perez JA, et al. EV-D68 Infection in Children With Asthma Exacerbation and Pneumonia in Mexico City During 2014 Autumn. Influenza Other Respir Viruses. 2016;10(3):154-60. PubMed PMID: 26935868.
TY - JOUR
T1 - EV-D68 infection in children with asthma exacerbation and pneumonia in Mexico City during 2014 autumn.
AU - Vazquez-Perez,Joel A,
AU - Ramirez-Gonzalez,Jose E,
AU - Moreno-Valencia,Yazmin,
AU - Hernandez-Hernandez,Victor A,
AU - Romero-Espinoza,Jose A I,
AU - Castillejos-Lopez,Manuel,
AU - Hernandez,Andres,
AU - Perez-Padilla,Rogelio,
AU - Oropeza-Lopez,Lizbeth E,
AU - Escobar-Escamilla,Noe,
AU - Gonzalez-Villa,Maribel,
AU - Alejandre-Garcia,Alejandro,
AU - Regalado-Pineda,Justino,
AU - Santillan-Doherty,Patricio,
AU - Lopez-Martínez,Irma,
AU - Diaz-Quiñonez,Alberto,
AU - Salas-Hernandez,Jorge,
PY - 2016/02/24/accepted
PY - 2016/3/4/entrez
PY - 2016/3/5/pubmed
PY - 2016/12/20/medline
KW - Enterovirus D68
KW - epidemiology
KW - outbreak
KW - pediatric
KW - respiratory viruses
SP - 154
EP - 60
JF - Influenza and other respiratory viruses
JO - Influenza Other Respir Viruses
VL - 10
IS - 3
N2 - BACKGROUND: Human enterovirus D68 (EV-D68) recently caused an increase in mild-to-severe pediatric respiratory cases in North America and some European countries. Even though few of these children presented with acute paralytic disease, direct causal relationship cannot yet be assumed. OBJECTIVES: The purposes of this report were to describe the clinical findings of an outbreak of EV-D68 infection in Mexico City and identify the genetic relationship with previously reported strains. PATIENTS/METHODS: Between September and December 2014, 126 nasopharyngeal samples (NPS) of hospitalized children <15 years of age with ARI were tested for the presence of respiratory viruses using a multiplex RT-qPCR and EV-D68-specific RT-qPCR. Clinical, epidemiological, and demographic data were collected and associated with symptomatology and viral infections. Phylogenetic analyses were performed using VP1 region. RESULTS: Enterovirus/rhinovirus infection was detected in 40 patients (31·7%), of which 24 patients were EV-D68-positive. EV-D68 infection prevailed over September and October 2014 and was associated with neutrophilia and lymphopenia, and patients were more likely to develop hypoxemia. Phylogenetic analyses showed that Mexican EV-D68 belongs to the new B1 clade. CONCLUSIONS: This is the first EV-D68 outbreak described in Mexico and occurred few weeks after the United States reported similar infections. Although EV-D68 belongs to new B1 clade, no neurological affection was observed.
SN - 1750-2659
UR - https://www.unboundmedicine.com/medline/citation/26935868/EV_D68_infection_in_children_with_asthma_exacerbation_and_pneumonia_in_Mexico_City_during_2014_autumn_
DB - PRIME
DP - Unbound Medicine
ER -
