Tags

Type your tag names separated by a space and hit enter

MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS AND MATERNAL CORTISOL LEVELS INTERACT TO PREDICT INFANT CORTISOL LEVELS.
Infant Ment Health J. 2016 Mar-Apr; 37(2):125-39.IM

Abstract

Three basic findings have emerged from research on maternal depressive symptoms and offspring hypothalamic-pituitary-adrenal functioning: (a) Mothers' depressive symptoms are positively associated with their offsprings' cortisol stress response, (b) numerous individual and interpersonal maternal characteristics moderate this association, and (c) maternal and infant cortisol levels are highly correlated. In combination, these findings have suggested that maternal cortisol levels may moderate the relation between maternal depressive symptoms and infant cortisol responsivity; the current study assessed this hypothesis. Participants were 297 mother-infant dyads who were recruited from the community. Maternal depressive symptoms were assessed via self-report. Dyads participated in two differentially stressful infant challenges when infants were 16 and 17 months old. Mother and infant salivary cortisol was collected before and after challenges. Results indicate that maternal cortisol levels moderated associations between maternal depressive symptoms and infant cortisol levels across both challenges. Infants showed higher cortisol levels if their mothers had both higher depressive symptoms and higher cortisol levels, as compared to infants of mothers with higher depressive symptoms and lower cortisol, and to infants of mothers with lower depressive symptoms and either higher or lower cortisol levels. We discuss findings in relation to environmental and biological factors that may contribute to the intergenerational transmission of depressive symptoms.

Authors+Show Affiliations

Ryerson University.McMaster University.University of Toronto.Sunnybrook Health Sciences Centre.Sunnybrook Health Sciences Centre.Ryerson University.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26939829

Citation

Khoury, Jennifer E., et al. "MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS and MATERNAL CORTISOL LEVELS INTERACT to PREDICT INFANT CORTISOL LEVELS." Infant Mental Health Journal, vol. 37, no. 2, 2016, pp. 125-39.
Khoury JE, Gonzalez A, Levitan R, et al. MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS AND MATERNAL CORTISOL LEVELS INTERACT TO PREDICT INFANT CORTISOL LEVELS. Infant Ment Health J. 2016;37(2):125-39.
Khoury, J. E., Gonzalez, A., Levitan, R., Masellis, M., Basile, V., & Atkinson, L. (2016). MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS AND MATERNAL CORTISOL LEVELS INTERACT TO PREDICT INFANT CORTISOL LEVELS. Infant Mental Health Journal, 37(2), 125-39. https://doi.org/10.1002/imhj.21554
Khoury JE, et al. MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS and MATERNAL CORTISOL LEVELS INTERACT to PREDICT INFANT CORTISOL LEVELS. Infant Ment Health J. 2016 Mar-Apr;37(2):125-39. PubMed PMID: 26939829.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MATERNAL SELF-REPORTED DEPRESSIVE SYMPTOMS AND MATERNAL CORTISOL LEVELS INTERACT TO PREDICT INFANT CORTISOL LEVELS. AU - Khoury,Jennifer E, AU - Gonzalez,Andrea, AU - Levitan,Robert, AU - Masellis,Mario, AU - Basile,Vincenzo, AU - Atkinson,Leslie, Y1 - 2016/03/04/ PY - 2015/06/20/received PY - 2015/09/20/revised PY - 2015/11/21/accepted PY - 2016/3/5/entrez PY - 2016/3/5/pubmed PY - 2016/12/15/medline KW - Cortisol KW - HPA KW - Säugling KW - axe de l'HPA KW - cortisol KW - depresión materna KW - dépression maternelle KW - infant KW - infante KW - maternal depression KW - mütterliche Depression KW - nourrisson KW - コルチゾール KW - 乳幼児 KW - 嬰兒 KW - 母親の抑うつ KW - 母親抑鬱症 KW - 皮質醇 KW - 間脳下垂体副腎系 (HPA) SP - 125 EP - 39 JF - Infant mental health journal JO - Infant Ment Health J VL - 37 IS - 2 N2 - Three basic findings have emerged from research on maternal depressive symptoms and offspring hypothalamic-pituitary-adrenal functioning: (a) Mothers' depressive symptoms are positively associated with their offsprings' cortisol stress response, (b) numerous individual and interpersonal maternal characteristics moderate this association, and (c) maternal and infant cortisol levels are highly correlated. In combination, these findings have suggested that maternal cortisol levels may moderate the relation between maternal depressive symptoms and infant cortisol responsivity; the current study assessed this hypothesis. Participants were 297 mother-infant dyads who were recruited from the community. Maternal depressive symptoms were assessed via self-report. Dyads participated in two differentially stressful infant challenges when infants were 16 and 17 months old. Mother and infant salivary cortisol was collected before and after challenges. Results indicate that maternal cortisol levels moderated associations between maternal depressive symptoms and infant cortisol levels across both challenges. Infants showed higher cortisol levels if their mothers had both higher depressive symptoms and higher cortisol levels, as compared to infants of mothers with higher depressive symptoms and lower cortisol, and to infants of mothers with lower depressive symptoms and either higher or lower cortisol levels. We discuss findings in relation to environmental and biological factors that may contribute to the intergenerational transmission of depressive symptoms. SN - 1097-0355 UR - https://www.unboundmedicine.com/medline/citation/26939829/MATERNAL_SELF_REPORTED_DEPRESSIVE_SYMPTOMS_AND_MATERNAL_CORTISOL_LEVELS_INTERACT_TO_PREDICT_INFANT_CORTISOL_LEVELS_ L2 - https://doi.org/10.1002/imhj.21554 DB - PRIME DP - Unbound Medicine ER -