Tags

Type your tag names separated by a space and hit enter

[Dengue, Zika and Chikungunya].
Medicina (B Aires). 2016; 76(2):93-7.M

Abstract

Arboviruses are transmitted by arthropods, including those responsible for the current pandemic: alphavirus (Chikungunya) and flaviviruses (dengue and Zika). Its importance increased in the Americas over the past 20 years. The main vectors are Aedes aegypti and A. albopictus. Dengue infection provides long lasting immunity against the specific serotype and temporary to the other three. Subsequent infection by another serotype determines more serious disease. There is a registered vaccine for dengue, Dengvaxia (Sanofi Pasteur). Other two (Butantan and Takeda) are in Phase III in 2016. Zika infection is usually asymptomatic or occurs with rash, conjunctivitis and not very high fever. There is no vaccine or specific treatment. It can be transmitted by parental, sexual and via blood transfusion. It has been associated with microcephaly. Chikungunya causes prolonged joint pain and persistent immune response. Two candidate vaccines are in Phase II. Dengue direct diagnosis is performed by virus isolation, RT-PCR and ELISA for NS1 antigen detection; indirect methods are ELISA-IgM (cross-reacting with other flavivirus), MAC-ELISA, and plaque neutralization. Zika is diagnosed by RT-PCR and virus isolation. Serological diagnosis cross-reacts with other flavivirus. For CHIKV culture, RT-PCR, MAC-ELISA and plaque neutralization are used. Against Aedes organophosphate larvicides (temephos), organophosphorus insecticides (malathion and fenitrothion) and pyrethroids (permethrin and deltamethrin) are usually employed. Resistance has been described to all these products. Vegetable derivatives are less expensive and biodegradable, including citronella oil, which microencapsulated can be preserved from evaporation.

Authors+Show Affiliations

Comité de Redacción, Medicina (Buenos Aires), Buenos Aires, Argentina. E-mail: isabel.kantor@gmail.com.

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

26942903

Citation

Kantor, Isabel N.. "[Dengue, Zika and Chikungunya]." Medicina, vol. 76, no. 2, 2016, pp. 93-7.
Kantor IN. [Dengue, Zika and Chikungunya]. Medicina (B Aires). 2016;76(2):93-7.
Kantor, I. N. (2016). [Dengue, Zika and Chikungunya]. Medicina, 76(2), 93-7.
Kantor IN. [Dengue, Zika and Chikungunya]. Medicina (B Aires). 2016;76(2):93-7. PubMed PMID: 26942903.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Dengue, Zika and Chikungunya]. A1 - Kantor,Isabel N, Y1 - 2016/02/22/ PY - 2016/3/5/entrez PY - 2016/3/5/pubmed PY - 2016/8/23/medline KW - Argentina KW - arbovirus KW - chikungunya KW - dengue KW - zika SP - 93 EP - 7 JF - Medicina JO - Medicina (B Aires) VL - 76 IS - 2 N2 - Arboviruses are transmitted by arthropods, including those responsible for the current pandemic: alphavirus (Chikungunya) and flaviviruses (dengue and Zika). Its importance increased in the Americas over the past 20 years. The main vectors are Aedes aegypti and A. albopictus. Dengue infection provides long lasting immunity against the specific serotype and temporary to the other three. Subsequent infection by another serotype determines more serious disease. There is a registered vaccine for dengue, Dengvaxia (Sanofi Pasteur). Other two (Butantan and Takeda) are in Phase III in 2016. Zika infection is usually asymptomatic or occurs with rash, conjunctivitis and not very high fever. There is no vaccine or specific treatment. It can be transmitted by parental, sexual and via blood transfusion. It has been associated with microcephaly. Chikungunya causes prolonged joint pain and persistent immune response. Two candidate vaccines are in Phase II. Dengue direct diagnosis is performed by virus isolation, RT-PCR and ELISA for NS1 antigen detection; indirect methods are ELISA-IgM (cross-reacting with other flavivirus), MAC-ELISA, and plaque neutralization. Zika is diagnosed by RT-PCR and virus isolation. Serological diagnosis cross-reacts with other flavivirus. For CHIKV culture, RT-PCR, MAC-ELISA and plaque neutralization are used. Against Aedes organophosphate larvicides (temephos), organophosphorus insecticides (malathion and fenitrothion) and pyrethroids (permethrin and deltamethrin) are usually employed. Resistance has been described to all these products. Vegetable derivatives are less expensive and biodegradable, including citronella oil, which microencapsulated can be preserved from evaporation. SN - 0025-7680 UR - https://www.unboundmedicine.com/medline/citation/26942903/[Dengue_Zika_and_Chikungunya]_ L2 - http://www.medicinabuenosaires.com/PMID/26942903.pdf DB - PRIME DP - Unbound Medicine ER -